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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…By elucidating a mechanistic basis for the increased affinity of the N501Y mutant S1-RBD for ACE2, we believe that the results presented here will aid in developing therapeutic strategies against SARS-CoV-2 including designing of therapeutic agents targeting the ACE2-S1-RBD interaction.…”
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
Published 2021“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
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The investigation of treatment design parameters on carbon integration networks
Published 2023“…For this, an enhanced treatment model that captures all necessary treatment design parameters has been utilized alongside the original model. …”
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
Published 2021“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
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Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO<sub>2</sub> intercooled and reheated cycles under design and off‐d...
Published 2022“…At optimized conditions (<i>P</i><sub>c,o</sub> = 30 MPa, Pc,o = 8 MPa, TIT = 744°C, CIT = 30°C [wet‐cooling]), the ICC shows superior energetic performance (52.08%) compared to 47.97% for DRC, 49.20% for PIC, and 48.62% for RHC. At off‐design conditions with a power demand (PD) of 40% of the design load (50 MW), the thermal efficiency is decreased by 21.82% in DRC, 17.71% in ICC, 22.46% in PIC, and 13.60% in RHC. …”
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Ultra-Low Energy CNFET-Based Ternary Combinational Circuits Designs
Published 2021“…The target of this work is to decrease energy consumption by (1) using Multiple-valued logic (MVL) that shows notable enhancements regarding energy consumption over binary circuits and (2) using carbon nanotube field-effect transistors (CNFET) that show better performance than CMOS. …”
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Novel Ternary Adder and Multiplier Designs Without Using Decoders or Encoders
Published 2021“…Extensive simulations (over 160) of the proposed designs in terms of PVT (Process, Voltage, Temperature) variations, noise effect, and scalability studies, along with several benchmark designs using HSPICE simulator, prove the significance of the proposed circuits to decrease the power-delay product (PDP), improve the robustness to process variations, and the noise tolerance. …”
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Design and analysis of PV fed high-voltage gain DC-DC converter using PI and NN controllers
Published 2022“…To reuse the leakage-inductor (LI) energy of the CI with the help of a passive clamp circuit for reducing the voltage stress across the switch, similarly switch has less resistance so conduction losses also decreased. …”
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Design of an integrated system that combines the steam gasification of plastic waste and a solid oxide fuel cell for sustainable power generation
Published 2024“…The proposed system is designed using Aspen Plus v10® with two primary units. …”
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Solar Technology and District Cooling System in a Hot Climate Regions: Optimal Configuration and Technology Selection
Published 2022“…The PVT-DCS configuration has the lowest operation cost and the highest environmental performance by decreasing the global warming potential by 89.5%. The T-DCS configuration becomes economically competitive only at high electricity tariffs.…”
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Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
Published 2023“…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …”