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441
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
Published 2021“…We then used genetic and pharmacological methods to define the features of early motor dysfunction of α-synuclein-expressing C. elegans. …”
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442
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
Published 2023“…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. However, the cancer-related burden on patients, healthcare systems, and the economy is expected to expand; thus, cancer remains a significant public healthcare issue in Qatar. …”
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443
Recovery of business intelligence systems
Published 2018“…Saving the damage assessment time means shorter denial of service periods, which in turn guarantees the continuity of the patient centric healthcare system.…”
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444
Essays on the effect of excess compensation and governance changes on firm value
Published 2012“…Our results suggest that an increase in director excess compensation decreases the likelihood of CEO turnover, reduces the turnover-performance sensitivity, and increases managerial entrenchment. …”
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445
Biomarkers show promise for treatment of heart valve disease
Published 2015“…The researchers suggest that patients with increased pro- or decreased anti-calcific factors in their serum should avoid replacement with a bioprosthesis. …”
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446
Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
Published 2010“…The high rate of false-negative results is likely due to metabolic inhibition caused by chemotherapeutic drugs. …”
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447
Trace element composition of size-fractionated suspended particulate matter samples from the Qatari Exclusive Economic Zone of the Arabian Gulf: the role of atmospheric dust
Published 2020“…For several other elements (Cd, Cu, Mo, Zn, and Ca) the excess concentrations present after lithogenic correction are most likely of biogenic/anthropogenic origin. The excess concentrations, relative to average dust, for most elements (except Cd) decreased with distance from the shore, which may be due to differences in biology, currents, proximity to the coast, or interannual processes.…”
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448
Comparative study of the parameters affecting the performance of microchannels' heat exchangers: Latest advances review
Published 2023“…When the fluid is added with nanoparticles, like, Al2O3 and copper oxide (CuO) with different volumetric fractions (φ) of 0%, 0.5%, 1%, 1.5%, and 2%, the performance of the microchannel rises with rising the Reynolds number but conversely when the fluid is used in pure form the performance decreases with the rising value of Reynolds number. …”
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449
Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
Published 2020“…Females were 1.18 times more likely to have polypharmacy compared to males (95% CI: 1.03–1.34). …”
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450
Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
Published 2020“…Females were 1.18 times more likely to have polypharmacy compared to males (95% CI: 1.03–1.34). …”
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451
Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis
Published 2024“…In vitrectomized eyes, notable decreases were observed: at 30 min, the Ratio of Means (ROM) was 0.81 (95% CI: 0.53; 1.24), indicating a 19% reduction; at 60 min, the ROM of 0.833 (95% CI: 0.77; 0.89) showed a 16.7% reduction; at 90 min, the ROM of 0.757 (95% CI: 0.755; 0.758) corresponded to a 24.3% reduction; at 2 h, the ROM of 0.726 (95% CI: 0.642; 0.820) reflected a 27.4% reduction; at 3 h, the ROM of 0.692 (95% CI: 0.600; 0.797) resulted in a 30.8% reduction; and at 4 h, the ROM of 0.700 (95% CI: 0.363; 1.350) indicated a 30% reduction. …”
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452
The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
Published 2023“…<p dir="ltr">Dysregulated epigenetic modifications are common in lung cancer but have been reversed using demethylating agent like 5-Aza-CdR. 5-Aza-CdR induces/upregulates the NY-ESO-1 antigen in lung cancer. …”
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453