10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes حسب Goran Petrovski (129836)

"…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …"

Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills حسب Tariq Abbas (368053)

"…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …"

Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort حسب Mohamed Adil Shah Khoodoruth (14589828)

"…Multivariate analysis highlighted significant differences in platelet count, mean platelet volume (MPV), TG, HbA1c, BMI, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and ferritin among the groups. …"

Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers حسب Yadav, Santosh K.

"…Decreased FA along with both increased and decreased MD in different brain regions was present in HUC compared to CHNM. …"
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Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells حسب Sleiman, S.

"…Overexpression of hAT1R and hAT1R GFP decreased both basal cytosolic and nuclear Ca2+. In normal hVSMCs and low hAT1R GFP overexpressing hVSMCs, Ang II (10 15 to 10 4 M) induced a dose-dependent sustained increase of [Ca]c and [Ca]n with an EC50 near 5 × 10 11 and 5 × 10 9 M, respectively. …"
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma حسب Abou-Ghazal, Mohamed

"…In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …"
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Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss حسب Meritxell Espino Guarch (18810097)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: eLife<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.7554/elife.31511" target="_blank">https://dx.doi.org/10.7554/elife.31511</a></p>…"

Human Recombinant Arginase I (Co)-PEG5000-Induced Arginine Depletion of Breast Cancer Cell Lines Causes Autophagy Mediated Cell Death حسب Alayan, Moustapha

"…Breast cancer remains the most prevalent, life-threatening cancer in women, posing a dire global burden. …"
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Effects of COVID-19 on Autism Spectrum Disorder in Qatar حسب Fouad A. Alshaban (17281108)

"…Parents also reported decreased access to family and social support networks, as well as decreased quality of clinical and community support. …"

Impact of the positive pressure valve on vascular access device occlusions and bloodstream infections حسب Btaiche, Imad

"…With this potential for improving patient outcomes, decreasing costs, and facilitating nursing care and catheter management, the use of PPV devices becomes both advantageous and desirable. …"
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Clotted blood samples in the neonatal intensive care unit: A retrospective, observational study to evaluate interventions to reduce blood sample clotting حسب Matheus F. P. T. van Rens (17993767)

"…</p><h3>Aims</h3><p dir="ltr">To decrease the incidence of rejected blood samples taken for laboratory investigation as a result of clotted sample.…"

Indoor Air Quality (IAQ) in labor housing in Dubai and its impact on ccupants' health حسب Nazzal, Saja Bassam

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Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making حسب Almutairi, Adel F.

"…Results Study participants who were invited and completed the survey were 657. The percentage mean score of participants’ attitudes and concern was 70.1 ± 16.4 and 58.3 ± 15.3 respectively. …"
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications حسب Amr Nasr Fekry (22521185)

"…Comprehensive isotherm analysis revealed the Dubinin-Radushkevich model provided the best fit (R² = 0.998), indicating physical adsorption as the predominant mechanism, as the calculated mean free energy (E = 5.00 kJ/mol) falls within the 1–8 kJ/mol range characteristic of physical adsorption. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…Similarly, KO 47 mice also showed a slower rate of glucose clearance in GTT that was consistent with decreased mRNA expression of the GLUT4 gene in WAT but not in the muscle. …"

Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project حسب Mariam Al-Mutawa (18505317)

"…HAPI is a significant patient safety issue in hospitalized patients and can lead to increased healthcare costs and a decreased quality of life for patients . A retrospective data analysis identified issues such as knowledge gaps, lack of continuity of care, and nursing practice variations. …"

Evaluating the Successful Initiation of a New Dialysate Potassium Management Protocol: “Reduced Emergency Department Admission with Hyperkalemia in Hamad General Hospital Dialysis... حسب Shajahan Joseph K (18472465)

"…Potassium disorders, hyperkalemia, and hypokalemia are the most common electrolyte disturbances associated with life threating arrhythmias among dialysis patients. …"

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... حسب Samar, Shurbaji

"…Most of these TSH-LFIAs are designed for qualitative measurements (i.e., if TSH values > 5, or >15 IU/L) and as screening tests for primary hypothyroidism in children and adults. …"
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery حسب Stephen L. Atkin (6684368)

"…</p><p dir="ltr"><br></p><h3>Methods: </h3><p dir="ltr">Twenty-nine type 2 patients with severe obesity (mean BMI 46.2 kg/m²) and diabetes underwent Roux-en-Y gastric bypass (RYGB) surgery. …"

The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar حسب Komal Rafique (17075074)

"…</p> <h3>Conclusion</h3> <p>The results of this study suggest that in women with additional risk factors for FGR, the concurrent use of metformin significantly decreases the birthweight and increases the risk for LBW, SFD, PTB and admission to NICU. …"