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301
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…In summary, EMT-associated overexpression of PD-L1 was partially independent of promoter CpG methylation and more likely to be dependent on posttranslational histone modifications. …”
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302
eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Published 2018“…These effects are likely dependent on the inhibition of eIF4A activity since we observed similar results using PatA. …”
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303
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
Published 2024“…Incidence data were extracted from insurance claims and inpatient discharge sources and analysed with disease modelling meta-regression, version 2.1 (DisMod-MR 2.1). Years of life lost (YLLs) were estimated by combining death counts with standard life expectancy at the age of death. …”
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304
Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover
Published 2020“…We consider dicarbonyl stress, the functional vulnerability of the plant proteome to arginine-directed glycation and the likely role of methylglyoxal-mediated glycation in the activation of the unfolded protein response in plants. …”
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305
Hydrothermal and irreversibility numerical analysis of helical coil energy storage tank with nano-encapsulated PCMs: A comprehensive study with magnetic filled, Soret/Dufour, and m...
Published 2025“…On the other hand, average values of Nusselt and Sherwood are decreased with the rise of the Hartmann number. Furthermore, Nusselt average and Sherwood’s average decrease by 21.4 % and 24.9 % respectively when Darcy’s number increases from 0.1 to 10<sup>-4</sup>.…”
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306
Development and Mechanical Performance of Sustainable Geopolymer Concrete
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307
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
Published 2022“…However, its effective utilization is hindered by the adverse side effects associated with its administration, the detriment to the patients’ quality of life, and general toxicity to healthy fast-dividing cells. …”
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308
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
Published 2022“…However, its effective utilization is hindered by the adverse side effects associated with its administration, the detriment to the patients’ quality of life, and general toxicity to healthy fast-dividing cells. …”
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309
Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging
Published 2022“…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …”
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310
Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging
Published 2022“…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …”
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311
Carotid artery revascularization through a radiated field
Published 2003“…All patients had received previous radiation therapy within a mean interval of 10 years (range, 1-26 years), with average radiation dose of 62 Gy (range, 50-70 Gy). …”
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312
Evaluation of high-temperature reverse osmosis for recycling boiler blowdown in industrial applications
Published 2024“…The membrane rejection decreased from 97 % at 35°C to 92 % at 60°C; due to the increase in the diffusivities of ions at higher temperatures; however, the permeate quality met the boilers feedwater specifications. …”
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313
Zirconium Silicate/IL/Mxene-based composite membranes for high-temperature fuel cell applications
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314
Turkronicles: diachronic resources for the fast evolving Turkish language
Published 2025“…Despite the substantial vocabulary changes, we demonstrate that it is possible to identify old Turkish words that have the same meanings with newly coined ones using word embeddings. …”
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315
Quantitative Compressibility Effects in Thermal Elastohydrodynamic Circular Contacts
Published 2015“…The results reconfirm the well-known observations that minimum film thickness is very little affected by lubricant compressibility while central film thickness decreases linearly with the increase in volume compression of the lubricant. …”
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316
Analyzing the Influence of Climate and Anthropogenic Development on Vegetation Cover in the Coastal Ecosystems of GCC
Published 2025“…Our results revealed significant changes in land cover, as seen by an increase in artificial built-up areas by 15.5% in two decades and a corresponding decrease in bareland and dense vegetation. We also observed an increase in mangrove and seagrass areas, likely due to recent conservation and afforestation efforts. …”
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317
Innovative strategies to reduce traffic related injuries and deaths in youth
Published 2015“…Studies have shown young drivers are more likely to underestimate the probability of specific risks caused by traffic situations, as well as to overestimate their own driving skills making them more vulnerable to trauma. …”
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318
Stemming cardiovascular diseases in Qatar
Published 2015“…Many of the heart attack and stroke patients had diabetes, hypertension, high cholesterol, and/or were smokers, whereas controls were much less likely to have these factors.</p><p>All of these factors are associated with reduced physical activity and increased consumption of high-fat foods. …”
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319
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
Published 2015“…These findings provide novel insight into the suppressive action of MMP-8 on mammary tumorigenesis and metastasis, and indicate that the loss of MMP-8 likely has pleiotropic effects on innate immunity and angiogenesis that are reflected in changes in the protease web.…”
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320
A component analysis of positive behaviour support plans
Published 2012“…The most commonly implemented components of intervention were setting event changes and quality-of-life-based interventions. Conclusion Only treatment acceptability was found to be related to decreases in behavioural frequency. …”
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