Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development by Al Saneh, Mounir

“…Cleft lip and/or palate (CL/P) affects on average 1 in 700 live births and is considered to be the most common congenital craniofacial birth defect (Setó-Salvia and Stanier 2014). …”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
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Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making by Almutairi, Adel F.

“…In contrary, for every one unit increase in concern scores, the odds of enrollment decreased among study participants by 0.98 [0.97–0.99], adj.P = 0.017. …”
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Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application by Lama Soubra (11666333)

“…Pharmacists can play a substantial role in decreasing the burden of the disease.</p><h3>Purpose</h3><p dir="ltr">The primary aim of this study was to develop and validate a scale assessing the pharmacist role in hypertension management in the community pharmacy setting. …”

Vitamin D association with coagulation factors in polycystic ovary syndrome is dependent upon body mass index by Abu Saleh Md Moin (6189512)

“…<p dir="ltr">Polycystic ovary syndrome (PCOS) is associated with metabolic consequences including obesity and insulin resistance that are related to the excess prevalence of type 2 diabetes, hypertension, and cardiovascular diseases in later life. It is reported that PCOS subjects show marked platelet dysfunction and decreased plasma fibrinolytic activity, resulting in a prothrombotic state. …”

The thioredoxin homolog YbbN functions as a chaperone rather than as an oxidoreductase by Kthiri, Fatoum

“…Escherichia coli contains two thioredoxins, Trx1 and Trx2, and a thioredoxin-like protein, YbbN, which presents a strong homology in its N-terminal part with thioredoxins, and possesses a 20 kDa C-terminal part of unknown function. …”
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Wind shear coefficient, turbulence intensity and wind power potential assessment for Dhulom, Saudi Arabia by Rehman, Shafiqur

“…The study also includes the local values of air density calculated using temperature and pressure measurement made at 2 m AGL during the same period. The mean wind speed above 4 m/s and the standard deviation values were used to obtain the turbulence intensities (TI) at different heights. …”
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Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network by Fares Almomani (12585685)

“…An ANN model consists of three layers, 15 neutrons and 260 <i>epochs</i> accurately predict the CMP with 99.1% of data within ±10% deviation of the mean experimental value. The developed model can be used to forecast the CMP as a function of operating temperature, the substrate composition, and chemical dose, and can be used for scaling-up and cost analysis purposes.…”

Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting by Tawa Olukade (11619453)

“…</p><h3>Results</h3><p dir="ltr">The mean maternal age was 29.7 ± 5.5 years, prepregnancy BMI was 27.5 ± 5.8 kg/m2, GWG was 9.58 kg ± 6.87 kg and gestational age at birth was 38.5 ± 1.9 weeks. …”

Developing a Framework for improving Business Continuity Management success (BCM) in UAE Construction Industry by ALFALASI, ALMUR ABDULLA

“…Different kind of techniques such as frequency distribution, cross tabulation, One Way ANOVA, descriptive and pie charts as well as bar graphs Conclusion and recommendation Study concludes that labor work permit and Rain & flooding have highest mean. Larger spread value of sand storms and labor work permit factors explore that more spread out the observations are. …”
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Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills by Abbas, Tariq

“…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …”
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Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM) by Mohammad, Hadi Ahmad

“…All the scenarios present increasing minimum and maximum temperatures and decreasing precipitation, except for RCP8.5, which predicted a more adverse trend. …”
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Mortality and socio-economic outcomes among patients hospitalized for stroke and diabetes in the US: a recent analysis from the National Inpatient Sample by Aya Tabbalat (14150019)

“…In those patients, the mean (SD) age slightly decreased from 70 (13) years to 69 (13) years (p-trend < 0.001). …”

The impact of counseling on nutritional status among hematopoietic stem cell recipients: results of a randomized controlled trial by Jabbour, Jana

“…Studies assessing malnutrition rates in HSCT showed that malnutrition rates are low at admission (ranging between 4 and 6%), elevated at hospital discharge (ranging between 35 and 60%), and gradually decreases post discharge [2, 3]. A prospective cohort study suggested that even though patients had improved quality of life, physical activity levels, and lean body mass post HSCT, they did not regain their pre-HSCT levels 100 days post transplantation compared to admission. …”
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Properties and Microstructure Distribution of High-Performance Thermal Insulation Concrete by Malek Mohammad (17150977)

“…This material allows for better thermal insulation properties, thus decreasing the energy usage within the life cycle of the concrete structure. …”

Custom foot orthoses improve performance, but do not modify the biomechanical manifestation of fatigue, during repeated treadmill sprints by Olivier Girard (409080)

“…Regardless of footwear condition, mean horizontal forces, step frequency, vertical and leg stiffness decreased from sprint 1 to sprint 8 (all <i>P</i> < 0.001). …”

Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample by Menatalla Mekhaimar (14103708)

“…In patients with HF and DM, mean (SD) age slightly decreased from 71 (13) to 70 (13) years, in which 47.5% were males in 2005 as compared with 52% in 2014 (p trend < 0.001 for both). …”

A kinetic evaluation of nutrient and organic matter removal in greywater for green Walls: Assessing the performance of Mineral-Based, Organic, and Waste-Derived plant support media by Shaheeda Marakkar Anangadan (19239607)

“…<p dir="ltr">Greywater recycling provides a means to address rising water demand with reduced environmental impact due to its abundance and lightly polluted nature. …”

Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis by Fateen Ata (12217764)

“…Patients with pre-existing T1DM were more likely to have a six-month DKA recurrence than pre-existing T2DM. …”

Long-Haul Northeast Travel Disrupts Sleep and Induces Perceived Fatigue in Endurance Athletes by Christopher J. Stevens (3391547)

“…After this time, sleep duration returned to baseline for several days until it was very likely decreased on the night prior to competition (-1.2 ± 1.0 h; 1.18; ±0.93). …”