Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice by Charlotte Rinne (18766966)

“…<h3>Introduction</h3><p dir="ltr">Caloric restriction (CR) is a nutritional intervention that increases life expectancy while lowering the risk for cardio-metabolic disease. …”

A Scoping Review to Find Out Worldwide COVID-19 Vaccine Hesitancy and Its Underlying Determinants by Md. Rafiul Biswas (17293966)

“…<div><p>Background: The current crisis created by the coronavirus pandemic is impacting all facets of life. Coronavirus vaccines have been developed to prevent coronavirus infection and fight the pandemic. …”

Implementation of corporate governance rules and procedures in lebanese firms by Elgammal, Walid

“…It also helps the organization to determine the means to achieve its objectives and monitor its performance. …”
Get full text
Get full text
Get full text

An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat... by Merheb, Caroline

“…In both soils, tillage application decreased the densities, the aggregate mean weight diameter, the residual moisture content, and the fine pore volumes while increased the organic matter content, the porosity, the saturated hydraulic conductivity, and the amount of large pores of undisturbed soil. …”
Get full text
Get full text
Get full text

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 by Hedyeh Ebrahimi (7321358)

“…</p><p><br></p><h3>Methods</h3><p dir="ltr">Based on the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 methodology, we evaluated the incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs) of respiratory tract cancers (ie, tracheal, bronchus, and lung cancer and larynx cancer). …”

Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function by Sahar I. Da'as (17128747)

“…Many recent clinical and genetic studies have reported a series of CaM mutations in patients with life‐threatening arrhythmogenic syndromes, such as long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). …”

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Brittney S Sheena (9715568)

“…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …”

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... by Katherine R Paulson (8674293)

“…In 2019, 136 (67%) of 204 countries had a U5MR at or below the SDG 3.2 threshold and 133 (65%) had an NMR at or below the SDG 3.2 threshold, and the reference scenario suggests that by 2030, 154 (75%) of all countries could meet the U5MR targets, and 139 (68%) could meet the NMR targets. …”

Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 by Austin, Carter

“…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …”
Get full text
Get full text
Get full text

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

“…</p><p><br></p><h3>Interpretation</h3><p dir="ltr">In the absence of intervention, the annual toll of 7·69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades. …”

Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050 by Yingzhao, Jin

“…MethodsThe global prevalence, years lived with disabilities (YLDs), disability-adjusted life years (DALYs), projection, and inequality were estimated for early MSK diseases, including rheumatoid arthritis (RA), osteoarthritis (OA), low back pain (LBP), neck pain (NP), gout, and other MSK diseases (OMSKDs). …”
Get full text
Get full text
Get full text

The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global B... by Saeid Safiri (3713035)

“…</p><p><br></p><h3>Methods</h3><p dir="ltr">Vital registration, sample vital registration, verbal autopsy, and cancer registry data were used to generate incidence, death, and disability-adjusted life-year (DALY) estimates of colorectal cancer at the global, regional, and national levels. …”

New media and new practices of exploitation by Uzunoglu, Sarphan

“…Related issue of the magazine, was handling freelance working and exploitation relationship observing contemporary labor problems while it was also covering precarious labor relations and their reflections on media employees’ labor processes, contracts and working life. Some of the key concepts they focused on were involving member/subscriber/reader labor, alternative models regarding share of surplus value. …”
Get full text
Get full text
Get full text

Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Joseph L Ward (9715619)

“…We aimed to analyse data on the number of deaths, years of life lost, and mortality rates by sex and age group in people aged 10–24 years in 204 countries and territories from 1950 to 2019 by use of estimates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019.…”

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults by Nowell H, Phelps

“…FindingsFrom 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. …”
Get full text
Get full text
Get full text

Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Valery L Feigin (5320574)

“…During the same period, age-standardised rates of stroke incidence decreased by 17·0% (15·0–18·0), mortality decreased by 36·0% (31·0–42·0), prevalence decreased by 6·0% (5·0–7·0), and DALYs decreased by 36·0% (31·0–42·0). …”

Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …”

Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP) by Anas Hamad (9545771)

“…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. …”

Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro by Najem, Sonia A.

“…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …”
Get full text
Get full text
Get full text
Get full text

Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells by Tawil, Mirna

“…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …”
Get full text
Get full text
Get full text