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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
Published 2015“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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122
Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma
Published 2015“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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123
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Published 2017“…By contrast, mean blood pressure might have increased in east and southeast Asia, south Asia, Oceania, and sub-Saharan Africa. …”
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Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie
Published 2017“…The percentage of persons who achieved the target of HbA1c<7% increased from .7% at baseline to 39% at week 24. Mean FPG decreased significantly from 213.7 ± 60.1 mg/dL to 120.3 ± 25.7 mg/dL (P<.001), and mean PPG from 271 ± 65.3 mg/dL to 158.1 ± 36.4 mg/dL (P<.0001). …”
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126
Context-Tailored Food-Based Nutrition Education and Counseling for Pregnant Women to Improve Birth Outcomes: A Cluster-Randomized Controlled Trial in Rural Malawi
Published 2024“…We found no significant difference in mean birth weights recorded within 1 or 24 h of birth between the intervention and control groups. …”
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127
Aortic pulse wave velocity in renal transplant patients
Published 2004“…Results Aortic PWV was increased in subjects with renal transplants independently of age and mean blood pressure. …”
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128
Front dynamics of elliptical gravity currents on a uniform slope
Published 2017“…The Froude numbers (Fr) for the currents released with the same slope angle but different initial shapes are observed to attain a similar constant value after the second acceleration phase. The mean Froude number (Fr) is seen to increase with increasing slope angles. …”
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129
Simulation of the size-composition distribution of atmospheric nanoparticles over Europe
Published 2018“…The ground level concentrations of particles with a diameter larger than 100 nm (N100) were reproduced with a daily normalized mean error of 40 % and a daily normalized mean bias of −20 %. …”
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The effects of Ramadan fasting on clinical and biochemical markers among hemodialysis patients: A prospective cohort study
Published 2019“…RPFG also had slight increase in mean IDWG than RNFG by 0.35 kg (95% CI 0.11, 0.60). …”
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The Effect of Different Doses of Intravenous Dexmedetomidine on the Properties of Subarachnoid Blockade: A Systematic Review and Meta-Analysis
Published 2020“…</p><p><b>Results:</b> Intravenous dexmedetomidine, with loading dose of 1 mcg/kg, prolonged the sensory blockade duration of spinal anaesthesia by a mean difference of 49.6 min, P<0.001, and motor blockade duration by a mean difference of 44.7 min, P<0.001, while a loading dose of 0.5 mcg/kg prolonged the sensory blockade by a mean difference of 43.06 min, P<0.001, and motor blockade duration by a mean difference of 29.09 min, P<0.001. …”
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Effect of climate change on the annual energy consumption of a single family house in British Columbia
Published 2018“…This paper investigates the effect of climate change on the energy consumption of a single-family house with different energy efficiency levels, i.e. bylaw to meet current National Energy Code of Canada for Buildings (NECB), and passive house (PH) to meet the PH requirements under four climate zones in British Columbia, Canada. …”
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Neonatal Simulation Program: A 5 Years Educational Journey From Qatar
Published 2022“…The mean duration of PICC insertion has been improved from 39.7 ± 25 to 34.9 ± 12.4 min after implementing the program (<i>P</i> = 0.33). …”
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134
Portfolio Selection Problem Using CVaR Risk Measures Equipped with DEA, PSO, and ICA Algorithms
Published 2022“…Then, these methods were compared with the classic Mean-CVaR model. The results showed that the automotive price index was skewed to the right, and there was a possibility of an increase in return. …”
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135
Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
Published 2024“…The LST data derived from remote sensing sources demonstrates an upward trend for summer and a contrasting trend for winter. Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …”
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Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells
Published 2023“…Morphometric analysis of CAM showed that treatment with nano-formulated water-soluble kaempferol and combretastatin caused a substantial decrease in density, vessel network, branch points, and nets of CAM blood vessels. …”
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Outcome of home parenteral nutrition in 251 children over a 14-y period
Published 2016“…The major complications of HPN were catheter-related bloodstream infections (CRBSIs) (1.7/1000 d of PN) and intestinal failure-associated liver disease (IFALD) (51 children; 20% of cohort). An increased rate of CRBSIs was observed compared with our previous study, but we saw a decreasing trend since 2012. …”
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Development and Mechanical Performance of Sustainable Geopolymer Concrete
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140
National cholesterol education panel III. (c2005)
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masterThesis