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121
eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Published 2018“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”
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122
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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Managing Endothelial Dysfunction in COVID-19
Published 2022“…Secondary outcomes included the composite outcome of ICU admission or the need for mechanical ventilation, all-cause mortality, and the occurrence of side effects Results Of 42 randomized patients, 37 were included in the primary analysis. The mean age of the patients was 57 years; the mean BMI of study participants was 29.14. …”
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124
The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention
Published 2025“…No statistically significant difference in mean arterial pressure was observed between the two groups (MD -5.15, 95% CI [-10.38 to 0.08 mmHg], <i>P</i> = 0.09). …”
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Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials
Published 2023“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”
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126
Road safety and traffic medicine in Iran: Achievements and challenges
Published 2015“…<p dir="ltr">Road traffic injuries found to be the second rank of Years of Life Lost (YLL) and third rank of Disability Adjusted Life Years (DALY) in Iran based on Global Burden of Disease 2010. …”
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127
Outcome of home parenteral nutrition in 251 children over a 14-y period
Published 2016“…Results: A total of 251 patients were included: 217 (86%) had a PDD. The mean ± SD age at HPN onset was 0.7 ± 0.3 y, with a mean duration of 1.9 ± 0.4 y. …”
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128
Reducing terrorism with development ; the United Nations' new path. (c2009)
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129
Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover
Published 2020“…The latter is linked to the recent suggestion of protein glycation in sugar signaling in plant metabolism. …”
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130
Adsorption in nanopores with finite pore walls from truncated graphene
Published 2011“…This model mimics real carbon samples better than usually used infinite pore models, whatever is the assumed pore shape (slit-like, tubular, curved etc). In particular, it allows us to account for the adsorption at the pore edges, totally neglected in infinite models. …”
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131
Evaluation of the Surface Integrity and Recast Layer in Electrical Discharge Turning of WC-Co Composites
Published 2024“…<div><p>Tungsten carbide (WC) and its composites are typically associated with high hardness and high wear resistance, posing challenges in conventional machining processes like turning. To address the machining difficulties of WC-Co, electrical discharge turning (EDT) was proposed. …”
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132
The Role of KM in Enhancing AI Algorithms and Systems
Published 2020“…The main finding of the research was the massive impact of some KM processes like knowledge acquisition and knowledge creation on the different types of AI systems and algorithms to give an additional option for organizations during the implementation. …”
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133
The effects of blockchain implementation on Cyber risks mitigating strategies in the financial sector in the United Arab Emirates
Published 2018“…The statistical package for social sciences (SPSS) was used to analyze the responses by using different analysis techniques like Cronbach’s alpha, correlation test and regression test. …”
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134
Short-term outcomes of anterior cruciate ligament reconstruction with or without lateral tenodesis or anterolateral ligament reconstruction: a retrospective cohort
Published 2023“…However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.…”
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Modulation of Chronic Stress Outcomes by Dietary Sweeteners: A Comparative Study of Sucrose and Aspartame in Mice
Published 2025“…It has been suggested that sucrose consumption attenuates stress-induced cortisol secretion, whereas aspartame has been reported to increase activity of glucocorticoids and anxiety-like behavior in rodents Aim: The present study aimed to assess the differential effects of sucrose and aspartame on the physiological and behavioral response in chronic stress in mice. …”
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137
Exploring the potential of applying Sustainable Retrofitting Policies & Regulations for existing low-rise small-scale Residential Buildings (Villas) in Dubai, UAE
Published 2020“…Green retrofit for existing buildings has now become as one of the effective options to decrease energy consumption worldwide. It is crucial to develop sustainable retrofitting policies and regulations for the existing old villas since there is lack of regulations to retrofit old existing low scale residential buildings like villas in Dubai. …”
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138
Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition
Published 2003“…All groups showed a decrease in relative intestinal absorption with time. …”
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Glycemic Index of commonly consumed Lebanese mixed meals and desserts
Published 2010“…The determination of the Glycemic Index (GI) and Load (GL) for mixed meals serves as a dietetic tool in meal planning to reinforce the benefits of low GI meals and decrease the physiological effects of high GI meals. …”
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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
Published 2024“…MethodsUsing forecasts of major drivers of health such as the Socio-demographic Index (SDI; a composite measure of lag-distributed income per capita, mean years of education, and total fertility under 25 years of age) and the full set of risk factor exposures captured by GBD, we provide cause-specific forecasts of mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) by age and sex from 2022 to 2050 for 204 countries and territories, 21 GBD regions, seven super-regions, and the world. …”
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