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261
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. Sensitivity to arginine depletion using HuArgI (Co)-PEG5000 was evident in all of the tested PC cell lines with IC50 values in the pM range at 72 hours following treatment. …”
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262
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
Published 2024“…Incidence data were extracted from insurance claims and inpatient discharge sources and analysed with disease modelling meta-regression, version 2.1 (DisMod-MR 2.1). Years of life lost (YLLs) were estimated by combining death counts with standard life expectancy at the age of death. …”
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263
The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study
Published 2022“…In this single-centre, cumulative, prospective, registry study, 321 hypogonadal men (mean age: 58.9 years) received testosterone undecanoate injections in 12-week intervals for up to 12 years. …”
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264
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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265
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
Published 2022“…However, its effective utilization is hindered by the adverse side effects associated with its administration, the detriment to the patients’ quality of life, and general toxicity to healthy fast-dividing cells. …”
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266
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
Published 2022“…However, its effective utilization is hindered by the adverse side effects associated with its administration, the detriment to the patients’ quality of life, and general toxicity to healthy fast-dividing cells. …”
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267
Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging
Published 2022“…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …”
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268
Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging
Published 2022“…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …”
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269
A pathway to 25% reduction in greenhouse gas emission by 2030 using GIS-Based multi-criteria decision making for renewables, date palm (phoenix dactylifera), and carbon credits: a...
Published 2024“…<p dir="ltr">Qatar is making concerted efforts at the national level to decrease anthropogenic greenhouse gas emissions. The country has set its National Determined Contribution (NDC) in line with the Paris Agreement to reduce its overall emissions by 25% by the year 2030. …”
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270
Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells
Published 2023“…Morphometric analysis of CAM showed that treatment with nano-formulated water-soluble kaempferol and combretastatin caused a substantial decrease in density, vessel network, branch points, and nets of CAM blood vessels. …”
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271
Effect of speed and gradient on plantar force when running on an AlterG® treadmill
Published 2021“…<h3>Background</h3><p dir="ltr">Anti-gravity treadmills are used to decrease musculoskeletal loading during treadmill running often in return to play rehabilitation programs. …”
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272
Stemming cardiovascular diseases in Qatar
Published 2015“…Diabetes was the largest preventable risk factor to decrease heart attacks and strokes.</p><p>Heart attack and stroke are the leading causes of death and disability worldwide, which have killed an estimated 17.1 million people in 2004, according to the World Health Organization. …”
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273
Carotid artery revascularization through a radiated field
Published 2003“…All patients had received previous radiation therapy within a mean interval of 10 years (range, 1-26 years), with average radiation dose of 62 Gy (range, 50-70 Gy). …”
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274
Quantitative Compressibility Effects in Thermal Elastohydrodynamic Circular Contacts
Published 2015“…The results reconfirm the well-known observations that minimum film thickness is very little affected by lubricant compressibility while central film thickness decreases linearly with the increase in volume compression of the lubricant. …”
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275
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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276
Turkronicles: diachronic resources for the fast evolving Turkish language
Published 2025“…Despite the substantial vocabulary changes, we demonstrate that it is possible to identify old Turkish words that have the same meanings with newly coined ones using word embeddings. …”
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277
A component analysis of positive behaviour support plans
Published 2012“…The most commonly implemented components of intervention were setting event changes and quality-of-life-based interventions. Conclusion Only treatment acceptability was found to be related to decreases in behavioural frequency. …”
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278
Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
Published 2020“…The elderly population is the most susceptible to the negative effects of polypharmacy due to their altered pharmacokinetics and decreased drug clearance. Therefore, polypharmacy can lead to poor health status and higher rates of morbidity and mortality. …”
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279
Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
Published 2020“…The elderly population is the most susceptible to the negative effects of polypharmacy due to their altered pharmacokinetics and decreased drug clearance. Therefore, polypharmacy can lead to poor health status and higher rates of morbidity and mortality. …”
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280
Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…It also significantly reduced ad libitum energy intake, decreased hunger, and increased satiety in multiple trials. …”
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