SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs حسب Raed Shalaby (3756112)

"…Our results revealed that these selected chalcone analogs increased dopamine levels in the rat hepatoma (H4IIE) cells and decreased the relative mRNA expression of the MAO-B enzyme.…"

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S., El-Shoukrofy

"…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

On-site workshop investment problem: A novel mathematical approach and solution procedure حسب Nima Moradi (19418821)

"…These temporary OSWs are cost-effective, leading to decreasing the material handling cost and project makespan, which indicates their important role as a part of a construction project. …"

Annual performance assessment of an off‐grid and self‐sufficient sustainable climate refuge for hot arid climates حسب Fariha Niaz (14778319)

"…The electrical efficiency of the photovoltaic cells decreases from 16.87% to 15.24% with an increase in cell temperature from 309 K to 315 K. …"

Frugal innovation for sustainable rural development حسب Mokter Hossain (14634969)

"…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …"

Luspatercept's use in a patient with transfusion‐dependent beta‐thalassemia and intrathoracic extramedullary hematopoiesis (EMH) حسب Mohammed Najdat Seijari (17563263)

"…<h3>Key Clinical Message</h3><p dir="ltr">This case report and literature review examine the use of a relatively novel agent in a transfusion‐dependent beta‐thalassemia patient with extramedullary hematopoiesis (EMH). …"

Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? حسب Abu Saleh Md Moin (6189512)

"…SEMA3A was not different at baseline; at hypoglycemia, SEMA3A decreased in controls only. Post-hypoglycemia, SEMA3A levels were higher in T2D versus controls. sNRP1 did not correlate with ACE2, REN or AGT. …"

Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank حسب Mohammed Al-Hamdani (16962702)

"…<u>The Western Ontario and McMaster Universities Osteoarthritis Index</u> (WOMAC) is used to assess the severity of symptoms related to pain, stiffness, and function in diseased hip and knee joints. …"

Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer حسب Amal Ashour (6752957)

"…</p><h3>Results</h3><p dir="ltr">In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. This was driven by increased hexokinase-2 linked glucose metabolism and related increased MG formation. …"

Ratings of Perceived Exertion Misclassify Intensities for Sedentary Older Adults During Graded Cycling Test: Effect of Supramaximal High-Intensity Interval Training حسب Georges Jabbour (754884)

"…For both groups, RPE decreases with SCE at 10 min following graded test correlated significantly to V˙O₂ (r = 0.61, p < 0.01). …"

Development of new reliability metrics for microgrids: Integrating renewable energy sources and battery energy storage system حسب Mohammadreza, Gholami

"…The results demonstrate that the proposed indices effectively capture the contribution of RES to MG reliability and offer valuable insights for decision-making related to RES installation. Also, by integrating BESS, the contribution of RESs to outage hours and lost energy is effectively decreased from 89.41% and 87.41% to 32.69% and 28.94% respectively. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Trace Element Composition of Size Fractionated Suspended Particulate Matter Samples from the Qatari EEZ of the Arabian Gulf: The Role of Atmospheric Dust حسب Oguz Yigiterhan (14151006)

"…The excess concentrations, relative to average dust, for most elements (except Cd) decreased with distance from shore, which may be due to differences in biology, currents, proximity to the coast or interannual processes.…"

Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit حسب Fatima Khalifa Al-Sulaiti (14152056)

"…Inappropriate sampling time relative to the last dose was captured in 31% (<i>n</i> = 18) of the cases. …"

Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model حسب Haissam Abou-Saleh (497840)

"…However, potential side effects related to ChNP toxicity remain the major limitation hampering their wide application. …"

Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity حسب Mohammed R. Shaker (10316180)

"…Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …"

Qatar’s Evolving National Identity in Schools: A Twitter Perspective from 2015 to 2019 حسب Aisha Mohammed Al-Mansoor (20433395)

"…While the overall school twitter activity decreased over the years, the percentage of tweets by schools on nationalism remained high throughout the years, suggesting that it has remained an important topic post-blockade. …"

Driving and hypoglycemia حسب Stephen Beer (5480411)

"…Hypoglycemia is one of the major complications related to diabetes treatment. Many large studies have shown an increased risk of hypoglycemia with tight blood sugar control. …"

Non-diabetic ketoacidosis secondary to primary hyperthyroidism حسب Abdulrahman F. Al-Mashdali (17148316)

"…This was associated with decreased appetite and weight loss.</p><h3>Diagnosis</h3><p dir="ltr">Laboratory findings were significant for high anion gap metabolic acidosis, positive ketones in the urine, and high serum B-hydroxybutyrate. …"

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells حسب Mohamed Qasim Al-Fahdawi (17844209)

"…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …"

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy حسب Ajaz A. Bhat (12984701)

"…Overall, this is a relatively unexplored field that could provide crucial insights into tumor immunology and encourage the effective application of modulatory cytokine-chemokine therapy to EC.…"