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441
Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
منشور في 2024"…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …"
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article -
442
Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation
منشور في 2008"…Six eyes underwent fluorescein angiography at the 12-week follow-up visit; 3 (50%) of these eyes had decreased leakage compared with baseline. Both stabilization of vision and improved CMT were maintained for at least 8 weeks after a single injection in almost all eyes. …"
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article -
443
Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression
منشور في 2021"…Expression of FSCN1<sup>high</sup> (identified in BRCA dataset from TCGA) in conjunction with elevated expression of the top 10 upregulated or decreased expression of the top 10 downregulated genes (identified in our FSCN1<sup>CON</sup> vs. …"
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444
Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer c...
منشور في 2024"…F6 decreased MDA-MB-231 viability more than crude ZNE or its other fractions. …"
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445
Towards the development of an integrated model for examining the determinants affecting the use of Queue Management Solutions in Healthcare
منشور في 2021"…The results revealed that the new tool is beneficial, and the median times to finish the processes within the patient’s journey have significantly decreased. To evaluate the use of the enhanced QMS, this research develops an integrated model based on the integration of various constructs extracted from different theoretical models, including the UTAUT, TAM, and social cognitive theory (SCT) along with trust and innovativeness as external factors. …"
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446
Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
منشور في 2019"…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …"
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article -
447
Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells
منشور في 2015"…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …"
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article -
448
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
منشور في 2018"…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …"
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masterThesis -
449
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
منشور في 2023"…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. …"
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450
NMR Study of the Interaction of Trinitrobenzene with High-Spin Tetraarylporphinato-Iron(II1) Halides
منشور في 1981"…The averaged TNB shifts and line-widths are indicative of 1:1 complexes whose stability is decreased by more electron-withdrawing axial halides or phenyl substituents, consistent with the porphyrin acting as a π donor in the adduct. …"
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article -
451
The effects of a change in the point system on immigration
منشور في 2016"…In parallel, points for a subjective assessment of “adaptability” were decreased. In line with the initial objective, we find more French-speaking immigrants with bachelor’s degrees, and no worsening in labor market outcomes after the reform. …"
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article -
452
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453
3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction
منشور في 2022"…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. At first, simulation implemented on the comparison of the ground movements in the single and twin tunnels. …"
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454
Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells
منشور في 2021"…In this project, we first inspected ASS-1 expression in human breast cancer patients and found that it decreases progressively with tumorigenesis and metastasis. …"
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masterThesis -
455
Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment
منشور في 2020"…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …"
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masterThesis -
456
Efficiency of Azithromycin-Loaded Lipid Polymer Hybrid Nano-vehicle as a Repurposing formulation in Colon Cancer Management
منشور في 2025"…It displayed a safe profile on HT29 cell line, with the coated formulation having the lowest IC50= 24.17 μM at 24 hours that even decreases at longer time intervals, which confirms its potential for colorectal cancer management.…"
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masterThesis -
457
Intravitreal adalimumab in active noninfectious uveitis
منشور في 2016"…Seven out of 12 eyes had improvement of ≥2 ETDRS lines. Three out of three eyes had resolution of anterior chamber cells. …"
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article -
458
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
منشور في 2008"…WP1066 suppressed the phosphorylation of JAK2 and phosphorylation (Tyr705) of STAT3 in all three melanoma cell lines. In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …"
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conferenceObject -
459
miRNA-dependent regulation of STIM1 expression in breast cancer
منشور في 2019"…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …"
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460
Plasma volume variations in response to high intensity interval training in obese women: The influential role of menopausal status and age
منشور في 2025"…Following HIIT, only menopause status accounted for 19 % of the variation in PV decreases after warm-up and 21 % of the variation in PV decreases after SCT. …"
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article