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321
Molecular Analysis and Conformational Dynamics of Human MC4R Disease-Causing Mutations
Published 2022“…<div><p>Obesity is a chronic disease with increasing cases among children and adolescents. Melanocortin 4 receptor (MC4R) is a G protein-coupled transporter involved in solute transport, enabling it to maintain cellular homeostasis. …”
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322
Drug Delivery Systems Based on Polymeric Micelles and Ultrasound: A Review
Published 2016“…Once these drug-encapsulating nanoparticles reach the tumor site, an external stimulus, such as ultrasound, can be used to spatially and temporally trigger drug release. …”
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323
The Impact of Using Specialist Geotechnical Software in Modeling of Pile Raft Foundation (PRF)
Published 2019“…Since the Raft Foundations will be supported directly on soil, structural software like CSI SAFE do not simulate the exact site conditions, since they model the soil only as springs. …”
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324
Dietary Calcium Intake of 1200 mg/d May Have Negative Correlation on Percent Body Fat
Published 2006“…The high-calcium group (intake ≥1200 mg/d) had a significantly higher mean caloric intake (P ≤ .01) and significantly lower percent body fat (P ≤ .05) than the low-calcium group (intake <1200 mg/d). …”
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325
Enhanced nucleate boiling heat transfer on bubble-induced assembly of 3D porous interconnected graphene oxide/silver nanowire hybrid network
Published 2022“…<p>Due to an increasing trend of size diminution, integration, and multifunctionality, the heat load on electronic devices is constantly increasing. …”
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326
Driving simulation sickness and the sense of presence: Correlation and contributing factors
Published 2021“…Importantly, designing buildings that replicate a real-world environment could increase SP and decrease SS. Moreover, designing high quality and resolution scenarios could also increase SP, thus decreasing the severity of SS symptoms. …”
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327
An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im...
Published 2020“…In terms of United Arab Emirates University (UAEU), there has been a decrease in STEM programs enrolment, while STEM graduates in UAEU has stayed steady at 1/3 STEM majors compared to 2/3 non-STEM programs. …”
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328
The burden of prostate cancer in North Africa and Middle East, 1990–2019: Findings from the global burden of disease study
Published 2022“…This study presents estimates of PCa prevalence, incidence, death, years-of-life-lost (YLLs), years-lived-with-disability (YLDs), disability-adjusted-life-years (DALYs), and the burden attributable to smoking during 1990-2019 in North Africa and Middle East using data of Global Burden of Diseases (GBD) Study 2019.…”
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329
Pattern of Postoperative Mortality After Esophageal Cancer Resection According to Center Volume
Published 2015“…Pulmonary complications were the most common, affecting 38.1 % of patients, followed by surgical site infection (15.5 %), cardiovascular complications (11.2 %), and anastomotic leak (10.2 %). …”
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330
Levels and indoor–outdoor relationships of PM10 and soluble inorganic ions in Beirut, Lebanon
Published 2009“…The observed high intra-site temporal variation (minimum of 34 and a maximum of 120 μg/m3) was attributed to the dynamic air masses passing over the Eastern Mediterranean region. …”
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331
Sustainable Urban Regeneration of Blighted Neighborhoods: The Case of Al Ghanim Neighborhood, Doha, Qatar
Published 2022“…As a result of the original population’s relocation to suburban developments, the district has deteriorated, lacking street activity and increasing indigent public space. The researchers examined the literature on urban regeneration, conducted site visits and observations, reviewed and described case study limitations, and identified factors that contribute to the creation of a sustainable neighborhood, based on urban qualities such as integrated networks and walkable streets, open and green public spaces, and the regeneration of the old urban fabric. …”
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332
Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
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333
Ultrasound-Mediated Release of Folate Targeted Liposomes
Published 2021Get full text
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334
Factors Affecting Tourists’ Attitude and the Visit Intention Towards the Kingdom of Saudi Arabia for Non-Religious Tourism
Published 2024“…Studying Saudi Arabia as a tourism destination is crucial due to its unique position as a pivotal site for both religious and non-religious tourism. …”
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335
Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden
Published 2021“…Alpine ecosystems are under increasing pressure due to tourism and recreational activities. …”
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336
Optical coherence tomography findings in autoimmune retinopathy
Published 2012“…Macular OCT showed reduced central macular and foveal thicknesses in 6 patients (mean thickness 143 ± 30 μm and 131 ± 29 μm respectively). …”
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337
Safety around schools
Published 2015“…<p dir="ltr">Around schools, increases in walking and cycling help to reduce traffic congestion and improve the road safety and neighborhood navigation skills of children. …”
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338
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
Published 2024“…Incidence data were extracted from insurance claims and inpatient discharge sources and analysed with disease modelling meta-regression, version 2.1 (DisMod-MR 2.1). Years of life lost (YLLs) were estimated by combining death counts with standard life expectancy at the age of death. …”
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339
A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells
Published 2008“…We hypothesized that WP1066, a novel STAT3 blockade agent, has marked antitumor activity, even against the melanoma metastasis to brain, a site typically refractory to therapies. Experimental Design The antitumor activities and related mechanisms of WP1066 were investigated both in vitro on melanoma cell lines and in vivo on mice with subcutaneously syngeneic melanoma or with intracerebral melanoma tumors. …”
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A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce...
Published 2008“…We hypothesized that WP1066, a novel STAT3 blockade agent, has marked antitumor activity, even against the melanoma metastasis to brain, a site typically refractory to therapies. Experimental Design: The antitumor activities and related mechanisms of WP1066 were investigated both in vitro on melanoma cell lines and in vivo on mice with subcutaneously syngeneic melanoma or with intracerebral melanoma tumors. …”
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