12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase حسب Amira Othman (380131)

"…In vivo studies were performed using Ins^2Akita mice treated with or without the 12/15-LOX inhibitor baicalein. …"

Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats حسب Barakat, Ghinwa

"…Diabetic rats were injected intraperitoneally with 0.03 μg exendin-4/kg body weight/daily or treated with 5 ppm selenium in drinking water for a period of 4 weeks. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study حسب Obaidullah Zafar (17910572)

"…The aim of this study is to retrospectively evaluate outpatients with iron deficiency anemia who refused blood transfusion and were treated with intravenous iron supplementation. This study is a retrospective study based on medical records. …"

Thermodynamic analysis of solar-driven integrated system for efficient brine management and hydrogen production حسب Nadira Salsabila (16855101)

"…Rejected brine from the RO process is treated using reverse electrodialysis (RED) and the photo-chloralkali (PCA) process to produce valuable chemicals, including hydrogen, which is converted into electricity using a proton exchange membrane (PEM) fuel cell. …"

Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells حسب Ejlal Abu-El-Rub (5168183)

"…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…"

The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties حسب Jelena Eric (21015107)

"…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …"

Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy حسب Jia-Zhen Wu (6844793)

"…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …"

Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species حسب Jennifer Bruder (323066)

"…<p dir="ltr">The preservation of our planet’s decreasing biodiversity is a global challenge. Human attitudes and preferences toward animals have profound impacts on conservation policies and decisions. …"

Effectiveness and specificity of a classroom-based group intervention in children and adolescents exposed to war in Lebanon حسب Dimassi, Hani

"…The rates of disorders peaked one month post-war and decreased over one year. There was no significant effect of the intervention on the rates of MDD, SAD or PTSD. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effect of structural remodeling (retraction and recoil) of the pipeline embolization device on aneurysm occlusion rate حسب Jou, L.-D.

"…On average, it increases its diameter by 0.23 mm and decreases its length by 2.88 mm within 6 months of initial deployment. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro حسب Najem, Sonia A.

"…Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF حسب Jabr, Vanessa

"…Interestingly, we also found that inhibition of autophagy in exercising 10-week-old mice decreases BDNF protein levels in the hippocampus as compared to the control exercising group. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells حسب Castellino, R.C.

"…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells حسب El Atat, Oula

"…While knocking down either RHO, GTPase did not affect p-AKT levels, and p-ERK decreased in response to the knocking down of RHOG, CDC42 or RAC1. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders حسب Jaunetta Hill (18255631)

"…More importantly, the proteome of treated cells displayed ~75% of the downregulated products as SP1 targets. …"

Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants حسب Snigdhendubala Pradhan (9872262)

"…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …"

Successful endoscopic management of gastrojejunal anastomotic strictures after Roux-en-Y gastric bypas حسب Azar, Riad

"…Dilation to at least 15 mm is safe and decreases the need for further endoscopic dilation.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Seroprevalence of camel brucellosis in Qatar حسب Hashim Alhussain (9167136)

"…Camels below breeding age (i.e., < 4 years old) showed decreased seropositivity (3.4%, 95% CI, 0.1–17.8), compared to (22.8%, 95% CI, 17.4–29.0) seropositivity in camels ≥ 4 years of age, with a significant association between age groups and seropositivity (<i>P</i> = 0.02). …"

Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models حسب Ben Romdhane, Haifa

"…An extended dataset will enable a means to independently validate the defined models and test other modelling approaches. …"
احصل على النص الكامل