Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy حسب Samson Mathews Samuel (18808246)

"…We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …"

Orofacial Clefts حسب El Baba, Nada

"…Through whole genome sequencing, we identified three variant genes, ARHGEF18, CUL7, and EPDR1, that we could link to the cleft phenotype. Through functional assays to test the discrepancy in the behavior of both sets of cells, we assessed proliferation, motility, adhesion, and Rho GTPase activity. …"
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Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review حسب Ibrahim, Mihad

"…However, its effective utilization is hindered by the adverse side effects associated with its administration, the detriment to the patients’ quality of life, and general toxicity to healthy fast-dividing cells. …"
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Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review حسب Ibrahim, Mihad

"…However, its effective utilization is hindered by the adverse side effects associated with its administration, the detriment to the patients’ quality of life, and general toxicity to healthy fast-dividing cells. …"
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Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging حسب Farooq, Afifa

"…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …"
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Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging حسب Farooq, Afifa

"…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …"
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Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials حسب Pieter Francsois, Fouche

"…This meta-analysis indicated an 11% decrease in the death risk at 1 month after TXA use (odds ratio [OR] 0.89, 95% confidence interval [CI] 0.84 to 0.95) with a number needed to treat of 61 to avoid 1 additional death. …"
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…Materials and Methods: AML cells (U937) were treated with various concentrations of TP and AG, alone and in combination. …"
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Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019 حسب Sarah Naja (9954737)

"…<h3>Background</h3><p dir="ltr">Cumulative evidence suggests that early identification of anxiety in pregnancy is important, given that antenatal anxiety has been linked to morbid outcomes in expecting mothers and their offspring. …"

Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover حسب Naila Rabbani (291722)

"…We consider dicarbonyl stress, the functional vulnerability of the plant proteome to arginine-directed glycation and the likely role of methylglyoxal-mediated glycation in the activation of the unfolded protein response in plants. The latter is linked to the recent suggestion of protein glycation in sugar signaling in plant metabolism. …"

Turkronicles: diachronic resources for the fast evolving Turkish language حسب Togay Yazar (22828175)

"…Despite the substantial vocabulary changes, we demonstrate that it is possible to identify old Turkish words that have the same meanings with newly coined ones using word embeddings. …"

Quantitative Compressibility Effects in Thermal Elastohydrodynamic Circular Contacts حسب Habchi, W.

"…The results reconfirm the well-known observations that minimum film thickness is very little affected by lubricant compressibility while central film thickness decreases linearly with the increase in volume compression of the lubricant. …"
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Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows حسب Tohid Adibi (17871551)

"…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …"

Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy... حسب Hmwe Hmwe, Kyu

"…We calculated diarrhoeal disability-adjusted life-years (DALYs) as the sum of years of life lost (YLLs) and years lived with disability (YLDs) for each location, year, and age–sex group. …"
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Phase II National Study: Job Satisfaction and Workplace Environment Among Community Pharmacists in Lebanon: Pre and Post Economic Crisis حسب Salaheddin, Amira Talaat

"…The survey was administered via a link sent to pharmacists through SMS and WhatsApp, with follow-up calls to encourage participation. …"
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Seasonal variations of trace metal chemical forms in bed sediments of a karstic river in Lebanon حسب Korfali, Samira Ibrahim

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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. حسب Sara, Sokary

"…It also significantly reduced ad libitum energy intake, decreased hunger, and increased satiety in multiple trials. …"
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A component analysis of positive behaviour support plans حسب Grey, Ian

"…The most commonly implemented components of intervention were setting event changes and quality-of-life-based interventions. Conclusion Only treatment acceptability was found to be related to decreases in behavioural frequency. …"
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Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application حسب Lama Soubra (11666333)

"…Pharmacists can play a substantial role in decreasing the burden of the disease.</p><h3>Purpose</h3><p dir="ltr">The primary aim of this study was to develop and validate a scale assessing the pharmacist role in hypertension management in the community pharmacy setting. …"

Vitamin D association with coagulation factors in polycystic ovary syndrome is dependent upon body mass index حسب Abu Saleh Md Moin (6189512)

"…<p dir="ltr">Polycystic ovary syndrome (PCOS) is associated with metabolic consequences including obesity and insulin resistance that are related to the excess prevalence of type 2 diabetes, hypertension, and cardiovascular diseases in later life. It is reported that PCOS subjects show marked platelet dysfunction and decreased plasma fibrinolytic activity, resulting in a prothrombotic state. …"