Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation by Larissa Haertle (3864310)

“…Furthermore, T21 patients have a high risk of developing Alzheimer’s disease (AD) early in life, characterized by the presence of senile plaques of amyloid protein and neurofibrillary tangles, leading to neuronal loss and cognitive decline. …”

From past famines to present crises: The epigenetic impact of maternal malnutrition on offspring health in Gaza by Mohamed Adil Shah Khoodoruth (14589828)

“…It was shown that first-trimester exposure to severe famine during the Dutch Hunger Winter was associated with increased risk of schizophrenia in offsprings (Hoek et al., 1998). …”

Comparative effectiveness of one versus two doses of COVID-19 vaccines in Qatar: Evidence of converging protection over time by Hiam Chemaitelly (439114)

“…In contrast to the gradual buildup of protection against infection, single-dose effectiveness against severe, critical, or fatal COVID-19 increased rapidly for all three vaccines, exceeding 85 % by day 21 and closely matching the protection achieved after two doses.…”

Maternal–Neonatal Methylome Signatures In Preterm Birth Revealed By Long-Read DNA Methylation Profiling by BalaSubramani Gattu Linga (19325617)

“…Epigenetic regulation, particularly DNA methylation, is increasingly recognized as a key mediator of these processes, yet dual maternal-neonatal methylation landscapes in PTB remain insufficiently characterized. …”

Causes of construction reworks and their mitigation strategies by HAYAT, KAMRAN

“…By reducing the reworks , client feel more comfortable and satisfied, company market value increases ,less wastage of material, reduce waste and time, fatigue and tension will be less among staff , more comfortable and safe work environment can be achieved. …”
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Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults by Nowell H, Phelps

“…InterpretationThe combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. …”
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Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Brittney S Sheena (9715568)

“…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …”

Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease St... by Jessica A, Kerr

“…From 2022 to 2050, global increases in overweight (not obesity) prevalence are forecasted to stabilise, yet the increase in the absolute proportion of the global population with obesity is forecasted to be greater than between 1990 and 2021, with substantial increases forecast between 2022 and 2030, which continue between 2031 and 2050. …”
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New media and new practices of exploitation by Uzunoglu, Sarphan

“…Today, in new media sphere, tracking technologies replaced rating systems and data about consumer is being sold. Increasing use of new media and increasing Internet penetration through rising sales numbers of mobile devices caused a necessity for a new debate. …”
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Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 by Gregory A. Roth (6302315)

“…The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. …”

Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050 by Yingzhao, Jin

“…Between 1990 and 2019, the slope index of inequality increased for six MSK disorders, and the relative concentration index increased for gout, NP, OA, and OMSKDs but decreased for LBP and RA. …”
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Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Valery L Feigin (5320574)

“…From 1990 to 2019, the absolute number of incident strokes increased by 70·0% (67·0–73·0), prevalent strokes increased by 85·0% (83·0–88·0), deaths from stroke increased by 43·0% (31·0–55·0), and DALYs due to stroke increased by 32·0% (22·0–42·0). …”

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Bur... by Rafael, Lozano

“…We constructed the UHC effective coverage index by weighting each effective coverage indicator relative to its associated potential health gains, as measured by disability-adjusted life-years for each location-year and population-age group. …”
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Effectiveness and specificity of a classroom-based group intervention in children and adolescents exposed to war in Lebanon by Dimassi, Hani

“…These findings have significant policy and public health implications, given current practices of delivering universal interventions immediately post-war.…”
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Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review by Ibrahim, Mihad

“…Nanoparticles can be used as vehicles for the localized delivery and release of DOX, decreasing the effects on neighboring healthy cells and providing more control over the drug’s release and distribution. …”
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Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review by Ibrahim, Mihad

“…Nanoparticles can be used as vehicles for the localized delivery and release of DOX, decreasing the effects on neighboring healthy cells and providing more control over the drug’s release and distribution. …”
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Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000–17 by Kirsten E Wiens (9153854)

“…Increases in ORS use corresponded with declines in RHF in many locations, resulting in relatively constant overall ORT coverage from 2000 to 2017. …”

Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment by Farhat, Peter

“…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …”
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Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms by ALBLOOSHI, ROUDHA KHALID ABDULLA

“…This improvement led to decreased warranty claims, cost reductions, and enhanced product longevity, ultimately reinforcing the company's commitment to delivering high-quality products that exceed the customer's expectations. …”
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Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful? by Abdalla, Eddie K.

“…Importantly, bevacizumab decreases the incidence and severity of sinusoidal injury with oxaliplatin therapy. …”
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