Recombinant Adeno-Associated Virus-Mediated In Utero Gene Transfer Gives Therapeutic Transgene Expression in the Sheep by Abi Nader, Khalil

“…Somatic in utero gene therapy aims to treat congenital diseases where pathology develops in perinatal life, thereby preventing permanent damage. The aim of this study was to determine whether delivery of self-complementary (sc) adeno-associated virus (AAV) vector in utero would provide therapeutic long-term transgene expression in a large animal model. …”
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Using simulations to develop the quality of grade four students' explanations of inheritance and heredity. (c2012) by Moussa, Houida Jamil

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Ervilia castanea (Mollusca, Bivalvia) populations adversely affected at CO₂ seeps in the North Atlantic by Marta Martins (69128)

“…This raises concerns about the effects of ocean acidification on the brood stock of this species and other bivalve molluscs with similar life history traits.</p><h2>Other Information</h2><p dir="ltr">Published in: Science of The Total Environment<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.scitotenv.2020.142044" target="_blank">https://dx.doi.org/10.1016/j.scitotenv.2020.142044</a></p>…”

Lipid profile in Parkinson's disease: The potential role of brain-derived neurotrophic factor by Mahmoud A. Alomari (14780446)

“…<h3>Background</h3><p dir="ltr">Parkinson's disease is a neurodegenerative disease manifested as increased tremor, bradykinesia, rigidity, and postural instability. …”

A novel design for battery cooling based on highly thermally conductive phase change composites encapsulated by 3D printed polyethylene/boron nitride layer by Safna Nishad (16932474)

“…However, their susceptibility to self-heating impacts their performance, service life, and safety. Thus, efficient thermal management devices are indispensable. …”

A novel IoT intrusion detection framework using Decisive Red Fox optimization and descriptive back propagated radial basis function models by Osama Bassam J. Rabie (21323741)

“…<p dir="ltr">The Internet of Things (IoT) is extensively used in modern-day life, such as in smart homes, intelligent transportation, etc. …”

Prediction of Multiple Clinical Complications in Cancer Patients to Ensure Hospital Preparedness and Improved Cancer Care by Regina Padmanabhan (14231606)

“…Myelosuppression due to treatment increases the risk of sepsis and mortality in hematological cancer patients with febrile neutropenia. …”

Inhibition of cytochrome P450 epoxygenase promotes endothelium-to-mesenchymal transition and exacerbates doxorubicin-induced cardiovascular toxicity by Hevna Dhulkifle (14724821)

“…Thus, identifying the pathway involved in this toxicity may help minimize chemotherapy risk and improve cancer patients’ quality of life. Recent studies suggest that Endothelial-to-Mesenchymal transition (EndMT) and endothelial toxicity contribute to the pathogenesis of DOX-induced cardiovascular toxicity. …”

The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects by Ilhame Diboun (3522413)

“…<p dir="ltr">Familial hypercholesterolemia (FH) is an inherited disease characterized by reduced efficiency of low-density lipoprotein-cholesterol (LDL-C) removal from the blood and, consequently, an increased risk of life-threatening early cardiovascular complications. …”

Challenges and opportunities in biogas conversion to microbial protein: A pathway for sustainable resource recovery from organic waste by Hafiz Muhammad Aamir Shahzad (6687767)

“…Concurrently, urban expansion significantly increases organic waste, undermining both economic and environmental sustainability. …”

Extent and Mitigation of Financial Toxicity of Immune Checkpoint Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma by Nabil E. Omar (9545756)

“…We also aim to explore potential solutions to improve access to life-saving therapies such as ICIs. We conducted an exploratory targeted review of the current literature focusing on therapeutic advancements, their accessibility, and innovative strategies to overcome FT. …”

Building thermal resilience framework (BTRF): A novel framework to address the challenge of extreme thermal events, arising from climate change by Mohammad Zaher Serdar (17191381)

“…Moreover, recently, the rate and the impacts of these extremes have increased, despite all the mitigation efforts, necessitating a resilience-based approach to address these challenges stemming from the accelerated global warming and the advent of climate change. …”

Developing a Framework for Evaluating Accessibility Density and Coverage by Trabulsi, Eyad B.

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Towards the Future of Leadership in UAE Organizations: Leveraging Diversity by Chaya, Shireen N.

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The Integration of Agile Methodology in the Development of Software Project by ALMHEIRI, MOHAMMED

“…Agile proponents have produced a number of assertions regarding the advantages of agile approaches, such as increased group productivity and effectiveness, improved software reliability, and business effectiveness. …”
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery by Stephen L. Atkin (6684368)

“…</p><p dir="ltr"><br></p><h3>Methods: </h3><p dir="ltr">Twenty-nine type 2 patients with severe obesity (mean BMI 46.2 kg/m²) and diabetes underwent Roux-en-Y gastric bypass (RYGB) surgery. …”

The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar by Komal Rafique (17075074)

“…</p> <h3>Conclusion</h3> <p>The results of this study suggest that in women with additional risk factors for FGR, the concurrent use of metformin significantly decreases the birthweight and increases the risk for LBW, SFD, PTB and admission to NICU. …”

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

“…</p><p><br></p><h3>Interpretation</h3><p dir="ltr">In the absence of intervention, the annual toll of 7·69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades. …”

Phase 1 and 2 Studies Demonstrate the Safety and Efficacy of Intraprostatic Injection of PRX302 for the Targeted Treatment of Lower Urinary Tract Symptoms Secondary to Benign Prost... by Abi-Habib, Ralph

“…Phase 1 subjects received increasing concentrations of PRX302 at a fixed volume; phase 2 subjects received increasing volumes per deposit at a fixed concentration. …”
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Prostate cancer burden in South Asia: A systematic analysis of global burden of disease data (1990–2021) by Vijay Kumar (377076)

“…<h3>Objectives</h3><p dir="ltr">The objectives of this study were to analyze trends in prostate cancer incidence, incidence, mortality, and disability‐adjusted life years (DALYs) from 1990 to 2021 via data from the Global Burden of Disease (GBD) study in South Asia. …”