eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways by Zvi Cramer (10742876)

“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”

Managing Endothelial Dysfunction in COVID-19 by Matli, Kamal

“…Secondary outcomes included the composite outcome of ICU admission or the need for mechanical ventilation, all-cause mortality, and the occurrence of side effects Results Of 42 randomized patients, 37 were included in the primary analysis. The mean age of the patients was 57 years; the mean BMI of study participants was 29.14. …”
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The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention by Almonzer Al-Qiami (22393303)

“…No statistically significant difference in mean arterial pressure was observed between the two groups (MD -5.15, 95% CI [-10.38 to 0.08 mmHg], <i>P</i> = 0.09). …”

Hepatoprotective activity of the wild carrot chloroform-based fraction against CCl4-induced liver toxicity in mice by Shebaby, W.

“…It also reversed the CCl4-induced decrease in SOD, CAT and GST levels thereby reducing significantly hepatic damage. …”
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Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials by Huzaifa Ahmad Cheema (16328980)

“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”

Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent by Nasreddine, Ghenwa

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DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma by El-Sitt, Sally

“…Finally, we detected an increase in p-ERK in StarD13 knockdown cells, uncovering a potential link between Rho GTPases and ERK activation.…”
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D 2IA: User-defined interval analytics on distributed streams by Awad, Ahmed

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Adsorption in nanopores with finite pore walls from truncated graphene by Firlej, Lucyna

“…This model mimics real carbon samples better than usually used infinite pore models, whatever is the assumed pore shape (slit-like, tubular, curved etc). In particular, it allows us to account for the adsorption at the pore edges, totally neglected in infinite models. …”
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Evaluation of the Surface Integrity and Recast Layer in Electrical Discharge Turning of WC-Co Composites by Mehdi Soleymani (3347741)

“…<div><p>Tungsten carbide (WC) and its composites are typically associated with high hardness and high wear resistance, posing challenges in conventional machining processes like turning. To address the machining difficulties of WC-Co, electrical discharge turning (EDT) was proposed. …”

The effects of blockchain implementation on Cyber risks mitigating strategies in the financial sector in the United Arab Emirates by SAADEH, YASSER MOHAMMED

“…The statistical package for social sciences (SPSS) was used to analyze the responses by using different analysis techniques like Cronbach’s alpha, correlation test and regression test. …”
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Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover by Naila Rabbani (291722)

“…The latter is linked to the recent suggestion of protein glycation in sugar signaling in plant metabolism. …”

Short-term outcomes of anterior cruciate ligament reconstruction with or without lateral tenodesis or anterolateral ligament reconstruction: a retrospective cohort by Ashraf T. Hantouly (14150319)

“…However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.…”

High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis by Nabil Shallik (15900256)

“…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …”

Investigating the Properties of Electrodeposited of Ni-P-ZrC Nanocomposite Coatings by Osama Fayyaz (17017686)

“…Successful coelectrodeposition of ZCNPs without any observable defects was carried out utilizing a modified Watts bath and optimized conditions. …”

EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis by Yahya, Fares

“…We then evaluate the proposed methods using machine learning classifiers. We carried out an experiment on nine subjects performing semantic vigilance task (Stroop color word test (SCWT)) for approximately 45 minutes. …”
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Modulation of Chronic Stress Outcomes by Dietary Sweeteners: A Comparative Study of Sucrose and Aspartame in Mice by Akil, Shaymaa

“…It has been suggested that sucrose consumption attenuates stress-induced cortisol secretion, whereas aspartame has been reported to increase activity of glucocorticoids and anxiety-like behavior in rodents Aim: The present study aimed to assess the differential effects of sucrose and aspartame on the physiological and behavioral response in chronic stress in mice. …”
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Exploring the potential of applying Sustainable Retrofitting Policies & Regulations for existing low-rise small-scale Residential Buildings (Villas) in Dubai, UAE by Albedwawi, Khulood

“…Green retrofit for existing buildings has now become as one of the effective options to decrease energy consumption worldwide. It is crucial to develop sustainable retrofitting policies and regulations for the existing old villas since there is lack of regulations to retrofit old existing low scale residential buildings like villas in Dubai. …”
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Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition by Bouclaous, Carmel

“…All groups showed a decrease in relative intestinal absorption with time. …”
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