PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…In summary, EMT-associated overexpression of PD-L1 was partially independent of promoter CpG methylation and more likely to be dependent on posttranslational histone modifications. …”

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways by Zvi Cramer (10742876)

“…These effects are likely dependent on the inhibition of eIF4A activity since we observed similar results using PatA. …”

Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows by Tohid, Adibi

“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover by Naila Rabbani (291722)

“…We consider dicarbonyl stress, the functional vulnerability of the plant proteome to arginine-directed glycation and the likely role of methylglyoxal-mediated glycation in the activation of the unfolded protein response in plants. …”

Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

“…Although mortality rates due to appendicitis decreased in all regions, there were large regional variations in the temporal trend in incidence. …”
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Boron doped silver-copper alloy nanoparticle targeting intracellular S. aureus in bone cells by Tahir Abdulrehman (8697696)

“…The binding of the targeting nanoparticles to infected osteoblasts as well as the visualization of live/dead bacteria due to treatment was carried out using fluorescence microscopy. …”

Wales’ tourists not a burden for local healthcare by Nature Research (16552612)

“…</p><p>Instead, they found that Welsh residents were responsible for the vast majority of unintentional injury presentations to the emergency department. They also found a decrease in non-resident presentations between 2006 and 2014, the data range that was studied.…”

Carotid artery revascularization through a radiated field by Lesèche, Guy

“…All patients had received previous radiation therapy within a mean interval of 10 years (range, 1-26 years), with average radiation dose of 62 Gy (range, 50-70 Gy). …”
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Quantitative Compressibility Effects in Thermal Elastohydrodynamic Circular Contacts by Habchi, W.

“…The results reconfirm the well-known observations that minimum film thickness is very little affected by lubricant compressibility while central film thickness decreases linearly with the increase in volume compression of the lubricant. …”
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Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows by Tohid Adibi (17871551)

“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”

Turkronicles: diachronic resources for the fast evolving Turkish language by Togay Yazar (22828175)

“…Despite the substantial vocabulary changes, we demonstrate that it is possible to identify old Turkish words that have the same meanings with newly coined ones using word embeddings. …”

Innovative strategies to reduce traffic related injuries and deaths in youth by Joanne Banfield (19794507)

“…Studies have shown young drivers are more likely to underestimate the probability of specific risks caused by traffic situations, as well as to overestimate their own driving skills making them more vulnerable to trauma. …”

Stemming cardiovascular diseases in Qatar by Nature Research (16552612)

“…Many of the heart attack and stroke patients had diabetes, hypertension, high cholesterol, and/or were smokers, whereas controls were much less likely to have these factors.</p><p>All of these factors are associated with reduced physical activity and increased consumption of high-fat foods. …”

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice by Julie Decock (44558)

“…These findings provide novel insight into the suppressive action of MMP-8 on mammary tumorigenesis and metastasis, and indicate that the loss of MMP-8 likely has pleiotropic effects on innate immunity and angiogenesis that are reflected in changes in the protease web.…”

Trends in the global, regional, and national burden of oral conditions from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021 by Eduardo, Bernabe

“…Furthermore, DALY rates of lip and oral cavity cancer decreased in the European region and the region of the Americas, while DALY rates of orofacial clefts decreased in all regions. …”
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Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development by Al Saneh, Mounir

“…Cleft lip and/or palate (CL/P) affects on average 1 in 700 live births and is considered to be the most common congenital craniofacial birth defect (Setó-Salvia and Stanier 2014). …”
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The thioredoxin homolog YbbN functions as a chaperone rather than as an oxidoreductase by Kthiri, Fatoum

“…Escherichia coli contains two thioredoxins, Trx1 and Trx2, and a thioredoxin-like protein, YbbN, which presents a strong homology in its N-terminal part with thioredoxins, and possesses a 20 kDa C-terminal part of unknown function. …”
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Wind shear coefficient, turbulence intensity and wind power potential assessment for Dhulom, Saudi Arabia by Rehman, Shafiqur

“…The study also includes the local values of air density calculated using temperature and pressure measurement made at 2 m AGL during the same period. The mean wind speed above 4 m/s and the standard deviation values were used to obtain the turbulence intensities (TI) at different heights. …”
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A new perspective on cardiovascular drift during prolonged exercise by Amine Souissi (9931616)

“…<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. …”

Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network by Fares Almomani (12585685)

“…An ANN model consists of three layers, 15 neutrons and 260 <i>epochs</i> accurately predict the CMP with 99.1% of data within ±10% deviation of the mean experimental value. The developed model can be used to forecast the CMP as a function of operating temperature, the substrate composition, and chemical dose, and can be used for scaling-up and cost analysis purposes.…”