Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells حسب Sleiman, S.

"…Overexpression of hAT1R and hAT1R GFP decreased both basal cytosolic and nuclear Ca2+. In normal hVSMCs and low hAT1R GFP overexpressing hVSMCs, Ang II (10 15 to 10 4 M) induced a dose-dependent sustained increase of [Ca]c and [Ca]n with an EC50 near 5 × 10 11 and 5 × 10 9 M, respectively. …"
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma حسب Abou-Ghazal, Mohamed

"…In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …"
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Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats حسب Rizk, Sandra

"…In this study, we investigated the effects of selenium or exendin-4 administration on the expression of glucagon-like peptide-1 receptor (GLP-1R), insulin receptor substrate-1 (IRS-1), and preproinsulin in the pancreas of diabetic rats. …"
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Visible Light Photocatalytic Activity of Ag/WO₃ Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark حسب Maha Matalkeh (17148358)

"…HRTEM, XPS analysis shows that the photocatalyst has a large sheet-like morphology with well-dispersed small metallic Ag particles (<3 nm) on the WO₃ nanoparticle's surface, with most particles near the edges. …"

Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy حسب Olfa Khalifa (10914452)

"…<div><p>Non-alcoholic fatty liver disease (NAFLD) is a common liver lesion that is untreatable with medications. Glucagon-like peptide-1 receptor (GLP-1R) agonists have recently emerged as a potential NAFLD pharmacotherapy. …"

Evaluation of high-temperature reverse osmosis for recycling boiler blowdown in industrial applications حسب Joel Minier-Matar (17052378)

"…The membrane rejection decreased from 97 % at 35°C to 92 % at 60°C; due to the increase in the diffusivities of ions at higher temperatures; however, the permeate quality met the boilers feedwater specifications. …"

Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments حسب Gunjan Dagar (9339276)

"…CAR-T therapy has achieved FDA approval for treating blood cancers like B-cell acute lymphoblastic leukemia, large B-cell lymphoma, and multiple myeloma by targeting CD-19 and B-cell maturation antigens. …"

Zirconium Silicate/IL/Mxene-based composite membranes for high-temperature fuel cell applications حسب Edwin, Reeves Nayagam

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Assessment of resin systems as solution for well integrity challenge in carbonate reservoirs حسب Albertus Retnanto (17269237)

"…These include cementing jobs, substantial design based on downhole conditions, material selection criticality, well construction performance, and technological resources. …"

Mixed siliciclastic-carbonate-evaporite sedimentation in an arid eolian landscape: The Khor Al Adaid tide-dominated coastal embayment, Qatar حسب John M., Rivers

"…The overall landward increase in salinity is accompanied by a decrease in the diversity of benthic fauna and their skeletal remains. …"
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Impact of the positive pressure valve on vascular access device occlusions and bloodstream infections حسب Btaiche, Imad

"…With this potential for improving patient outcomes, decreasing costs, and facilitating nursing care and catheter management, the use of PPV devices becomes both advantageous and desirable. …"
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Clotted blood samples in the neonatal intensive care unit: A retrospective, observational study to evaluate interventions to reduce blood sample clotting حسب Matheus F. P. T. van Rens (17993767)

"…</p><h3>Aims</h3><p dir="ltr">To decrease the incidence of rejected blood samples taken for laboratory investigation as a result of clotted sample.…"

Indoor Air Quality (IAQ) in labor housing in Dubai and its impact on ccupants' health حسب Nazzal, Saja Bassam

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Rapid mercury removal using living indigenous microalgal communities for water treatment applications حسب Amr Nasr Fekry (22521185)

"…Comprehensive isotherm analysis revealed the Dubinin-Radushkevich model provided the best fit (R² = 0.998), indicating physical adsorption as the predominant mechanism, as the calculated mean free energy (E = 5.00 kJ/mol) falls within the 1–8 kJ/mol range characteristic of physical adsorption. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…Similarly, KO 47 mice also showed a slower rate of glucose clearance in GTT that was consistent with decreased mRNA expression of the GLUT4 gene in WAT but not in the muscle. …"

Clinical characteristics and treatment outcomes of coats disease in a Saudi Arabian population حسب Al-Qahtani, Abdullah

"…Results: The most common presenting complaint was decreased visual acuity followed by strabismus and then leukocoria. …"
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From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease حسب Ahmad Raza (18205961)

"…This review focuses on the potential mechanisms associated with these two diseases, like insulin resistance, inflammation, oxidative damage, mitochondrial injury, and cell death. …"

Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar حسب Shuja Mohd Reagu (12051406)

"…Breastfeeding requires close physical contact and observance of hygienic measures like handwashing. Worries around contamination increase during the perinatal period and can be expressed as increase in obsessive compulsive symptoms. …"

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... حسب Samar, Shurbaji

"…Most of these TSH-LFIAs are designed for qualitative measurements (i.e., if TSH values > 5, or >15 IU/L) and as screening tests for primary hypothyroidism in children and adults. …"
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery حسب Stephen L. Atkin (6684368)

"…</p><p dir="ltr"><br></p><h3>Methods: </h3><p dir="ltr">Twenty-nine type 2 patients with severe obesity (mean BMI 46.2 kg/m²) and diabetes underwent Roux-en-Y gastric bypass (RYGB) surgery. …"