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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …”
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes
Published 2021“…The fact that apoA2 correlated with gestational age at delivery in both control women and women with GDM raises the hypothesis that apoA2 may be used as a biomarker of premature delivery, and this warrants further investigation.…”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
Published 2021“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
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Driving against the clock: Investigating the impacts of time pressure on taxi and non-professional drivers’ safety and compliance
Published 2024“…<p>Drivers often encounter time pressure, which can lead to riskier driving habits, decreased safety margins, and a higher chance of accidents. …”
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Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure
Published 2015“…We studied 27 cases from 1964 to 2014. Twenty drivers were prosecuted, and seven drivers were not. …”
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The Effect of Number of Corrugation on Crashworthiness of Aluminum Corrugated Tube under Lateral Loading
Published 2017“…The results show that tubes with corrugations have a higher mean crushing force which is directly proportional to the number of corrugations. …”
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…Furthermore, semaglutide was the only effective Glucagon Like Peptide-1 Receptor Agonist in reducing Low-Density Lipoprotein and total cholesterol levels, with mean differences of -0.16 mmol/L and -0.48 mmol/L, respectively. …”
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10
Influence of temperature on tire-pavement noise in hot climates: Qatar case
Published 2021“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
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The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i>
Published 2023“…<p dir="ltr">1p32.3 microdeletion/duplication is implicated in many neurodevelopmental disorders-like phenotypes such as developmental delay, intellectual disability, autism, macro/microcephaly, and dysmorphic features. …”
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Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload
Published 2024“…<p>Glucagon-like peptide-1 (GLP-1) agonists and GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) co-agonists are major treatment options for subjects with obesity and patients with type 2 diabetes mellitus (T2DM). …”
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Exploring beyond numeric weight loss: The metabolic effects of semaglutide
Published 2025“…Furthermore, semaglutide was the only effective Glucagon Like Peptide-1 Receptor Agonist in reducing Low-Density Lipoprotein and total cholesterol levels, with mean differences of −0.16 mmol/L and −0.48 mmol/L, respectively. …”
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Evidence-based safety education and training for traffic injury prevention
Published 2015“…Except for some interventions like post-license driver education which has strong evidence based on large number of participants, in most of the subject interventions more rigorous investigation is needed especially in low- and middle- income countries.…”
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Enhancing Security and Performance in Live VM Migration: A Machine Learning‐Driven Framework With Selective Encryption for Enhanced Security and Performance in Cloud Computing Envi...
Published 2025“…Rigorous experiments demonstrate its effectiveness, showcasing an average 51.82% reduction in downtime and an average 72.73% decrease in total migration time across diverse workloads. …”
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Effect of anions on the structural, morphological and dielectric properties of hydrothermally synthesized hydroxyapatite nanoparticles
Published 2019“…The εʹ and dielectric loss (εʹʹ) values for the HA nanoparticles decrease with increase in the applied frequency as well. …”