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61
The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis
منشور في 2013"…We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …"
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62
Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
منشور في 2020"…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …"
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masterThesis -
63
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
منشور في 2022"…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …"
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64
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65
Efficacy and safety of the newer oral hypoglycemic agents in patients with T2DM during Ramadan: A systematic review and meta-analysis
منشور في 2020"…Glucagon-like peptide (GLP-1) agonist therapy was associated with a significant decrease in Hb<sub>A1c</sub> (%) (SMD -0.68) and a non-significant decrease in weight (kg) (SMD -2.57) and systolic blood pressure (SBP) (mmHg) (SMD -3.50) after Ramadan. …"
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66
Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
منشور في 2017"…The SW1116 colon cancer cell line was treated with HC (1, 5, 10 and 25 μg/ml) and cell viability was evaluated with WST 1 assay kit. …"
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67
Utilization of the internet for physical activity and diet information and its influence on pregnant women’s lifestyle habits in Qatar
منشور في 2023"…Also, participants who used the internet for diet information a great deal were more likely to decrease the amount of sugary and fatty foods they ate compared to women who used the internet somewhat or very little (61.4, 45.2, and 18.2%, p < 0.001; respectively) and (50.9, 30.4, and 18.2%, p = 0.001; respectively).…"
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68
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
منشور في 2016"…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
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69
Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS
منشور في 2018"…<h3>Background</h3><p dir="ltr">Insulin resistance (IR) is the hallmark of PCOS and it is known that exercise may decrease it. What is unknown is whether exercise may mechanistically alter the underlying IR, attenuating the dynamic lipid induced IR in insulin resistant subjects.…"
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70
Improving the Performance Measurement Using Overall Equipment Effectiveness (OEE) in Borouge
منشور في 2023"…The main issue found relating to the two extruder production lines productivity was where availability and quality show a significant decrease. …"
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71
Percutaneous Aspiration Irrigation Drainage Technique in the Management of Septic Arthritis in Children
منشور في 2011"…Result: Apyrexia was obtained after a mean period of 2 days. The mean draining duration was 4.5 days. …"
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article -
72
Estimation of Virtual Trust on Driverless Cars using Type-1 Fuzzy logic
منشور في 2024"…On the other hand, problems with software like data security and dependability must be resolved. …"
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73
Curcumin encapsulated colloidal amphiphilic block co-polymeric nanocapsules
منشور في 2020"…The nanocapsules exhibited a >30–fold decrease in IC50, suggesting enhanced anticancer activity associated with curcumin encapsulation. …"
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74
The Antioxidant and Pro-apoptotic effects of Sternbergia clusiana Bulb Ethanolic Extract on Breast Cancer Cells in vitro
منشور في 2021"…MDA-MB-231 cells treated with SbBEE exhibited morphological and biochemical hallmarks of apoptosis that were detected through DNA fragmentation, the hyper-expression of phosphatidylserine on the outer leaflet of cells membrane and the upregulation of proteins able to mediate cell death through apoptosis (c-PARP, Bax/ Bcl2). The prominent decrease in ROS levels upon treatment confirmed the antioxidant property of the extract being investigated, highlighting the promising effect of SbBEE in breast cancer treatment.…"
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masterThesis -
75
Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
منشور في 2021"…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…"
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76
Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
منشور في 1983"…Following treatment of the hyperthyroidism, control was improved in 63%, with an 11-83% (mean 44%) decrease in insulin dosage in 59% of them. …"
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77
Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals
منشور في 2023"…Knowledge scores were higher among nurses holding a graduate degree (mean = 85; p < 0.05), and those who attended a training course (mean = 79; p < 0.05). …"
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78
Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
منشور في 2020"…In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …"
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79
Project Portfolio Management for Successful Major IT Projects in Global Telecommunication Organization
منشور في 2011"…The research indicated that these factors like scope, time and cost of a project are not enough to control IT projects and obtain the expected result. …"
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80
Towards secure private and trustworthy human-centric embedded machine learning: An emotion-aware facial recognition case study
منشور في 2023"…We find that input quantization partially degrades the efficacy of adversarial and backdoor attacks at the cost of a slight decrease in accuracy over clean inputs. By analyzing the explanations generated by SHAP, we identify that the decision of a FER model is largely influenced by features such as eyes, alar crease, lips, and jaws. …"