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281
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
منشور في 2008"…WP1066 suppressed the phosphorylation of JAK2 and phosphorylation (Tyr705) of STAT3 in all three melanoma cell lines. In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …"
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conferenceObject -
282
Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications
منشور في 2025"…It was found that increasing ZiF-8 decreases the swelling in different media and increases degradation in PBS media. …"
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283
Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury
منشور في 2024"…WD has been shown to impair cognitive function, decrease the brain's capacity to compensate for insult by affecting recovery as well as induce metabolic syndrome (MetS) which may be a risk factor for poor TBI prognosis. …"
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article -
284
Effect of StarD13 on colorectal cancer proliferation, motility and invasion
منشور في 2014"…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …"
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article -
285
Children safety risk factors in Khorasan Razavi province
منشور في 2015"…Walking almost inevitably involves crossing a road, where the desire line of the pedestrian conflicts with the higher speed. …"
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286
State‐dependent control of breathing by the retrotrapezoid nucleus
منشور في 2015"…Electroencephalogram, neck electromyogram, blood pressure, respiratory frequency (fR) and tidal volume (VT) were recorded in 28 conscious adult male Sprague–Dawley rats. Optogenetic stimulation of RTN with channelrhodopsin-2, or inhibition with archaerhodopsin, simulated an instantaneous increase or decrease of central chemoreceptor activity. …"
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article -
287
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
منشور في 2023"…Age-standardised prevalence, YLDs, and underlying causes of HF were compared by 5-year age groups (considering 15 years old and more), sex (male and female), and countries. FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
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article -
288
Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats
منشور في 2020"…Equally, it showed a rise of the apoptotic markers (a decrease in the expression of the Bcl-2 and an increase of the P53). …"
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289
Optical coherence tomography findings in autoimmune retinopathy
منشور في 2012"…Macular OCT showed reduced central macular and foveal thicknesses in 6 patients (mean thickness 143 ± 30 μm and 131 ± 29 μm respectively). …"
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article -
290
Reducing terrorism with development ; the United Nations' new path. (c2009)
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masterThesis -
291
Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
منشور في 2016"…However, diarrhoeal diseases were the leading cause of death in Somalia (186·7 deaths per 100 000 people) in 2013, which decreased by 26·9% since 1990. The leading cause of disability-adjusted life-years (DALYs) was ischaemic heart disease for males and lower respiratory infection for females. …"
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292
eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
منشور في 2018"…These effects are likely dependent on the inhibition of eIF4A activity since we observed similar results using PatA. …"
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293
The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study
منشور في 2022"…In this single-centre, cumulative, prospective, registry study, 321 hypogonadal men (mean age: 58.9 years) received testosterone undecanoate injections in 12-week intervals for up to 12 years. …"
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294
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
منشور في 2023"…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …"
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article -
295
Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover
منشور في 2020"…We consider dicarbonyl stress, the functional vulnerability of the plant proteome to arginine-directed glycation and the likely role of methylglyoxal-mediated glycation in the activation of the unfolded protein response in plants. …"
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296
ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder
منشور في 2017"…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …"
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297
A pathway to 25% reduction in greenhouse gas emission by 2030 using GIS-Based multi-criteria decision making for renewables, date palm (phoenix dactylifera), and carbon credits: a...
منشور في 2024"…<p dir="ltr">Qatar is making concerted efforts at the national level to decrease anthropogenic greenhouse gas emissions. The country has set its National Determined Contribution (NDC) in line with the Paris Agreement to reduce its overall emissions by 25% by the year 2030. …"
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298
Effect of speed and gradient on plantar force when running on an AlterG® treadmill
منشور في 2021"…<h3>Background</h3><p dir="ltr">Anti-gravity treadmills are used to decrease musculoskeletal loading during treadmill running often in return to play rehabilitation programs. …"
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299
Carotid artery revascularization through a radiated field
منشور في 2003"…All patients had received previous radiation therapy within a mean interval of 10 years (range, 1-26 years), with average radiation dose of 62 Gy (range, 50-70 Gy). …"
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article -
300
Quantitative Compressibility Effects in Thermal Elastohydrodynamic Circular Contacts
منشور في 2015"…The results reconfirm the well-known observations that minimum film thickness is very little affected by lubricant compressibility while central film thickness decreases linearly with the increase in volume compression of the lubricant. …"
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article