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361
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
منشور في 2011"…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …"
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article -
362
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
منشور في 2013"…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…"
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article -
363
Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation
منشور في 2008"…Results: Twelve eyes (92.3%) had stable or improved BCVA, and 8 eyes (61.5%) had at least 2 lines of vision improvement. The average BCVA improved from 20/203 at baseline to 20/113 at 12 weeks (P = 0.001). …"
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article -
364
PSA-activated proaerolysin as a prostate specific cancer therapy
منشور في 2006"…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …"
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conferenceObject -
365
The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013)
منشور في 2016"…In this study, we aim to determine a possible mechanism of action of kefir and to study its effect on the motility of colorectal and breast cancer cell lines. Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …"
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masterThesis -
366
Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer c...
منشور في 2024"…F6 decreased MDA-MB-231 viability more than crude ZNE or its other fractions. …"
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367
ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder
منشور في 2017"…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …"
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368
The impact of bank liquidity on the Lebanese banks’ risk taking behavior
منشور في 2018"…This conclusion might suggest that higher capital requirements under Basel III are likely to increase bank risk with the implementation of new liquidity ratio. …"
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article -
369
Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
منشور في 2020"…Males were predominant (89%), more likely to fall at workplace, fall from a greater height and have polytrauma than females. …"
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370
CRISPR-Cas Controls Cryptic Prophages
منشور في 2022"…Specifically, compared to the wild-type strain, reducing the amounts of specific interfering RNAs (crRNA) decreases growth by 40%, increases cell death by 700%, and prevents persister cell resuscitation. …"
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371
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
منشور في 2023"…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …"
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372
Preterm birth in low-middle income Countries
منشور في 2024"…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …"
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article -
373
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
منشور في 2022"…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …"
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374
A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion
منشور في 2023"…The limited requests for retribution are likely due to a sense of impunity and adaptation to cumulative trauma. …"
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article -
375
Evaluation of transportation network reliability during unexpected events with multiple uncertainties
منشور في 2016"…These uncertainties are likely due to the effect of natural disasters on road networks. …"
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article -
376
Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
منشور في 2019"…<h3>Context: </h3><p dir="ltr">Previously, we identified chromograninA positive hormone-negative (CPHN) cells in high frequency in human fetal and neonatal pancreas, likely representing nascent endocrine precursor cells. …"
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377
Fitness training and work productivity in Lebanon. (c2006)
منشور في 2006احصل على النص الكامل
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masterThesis -
378
StarD13 is a tumor suppressor in breast cancer that regulates cell motility and invasion
منشور في 2014"…In general, the more aggressive the tumor, the more rapidly it grows and the more likely it metastasizes. Members of the Rho subfamily of small GTP-binding proteins (GTPases) play a central role in breast cancer cell motility and metastasis. …"
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article -
379
Conflict in Ukraine and the unsettling ripples: implications on food systems and development in North Africa
منشور في 2024"…Algeria) will likely be able to mitigate the adverse effects on their citizens. …"
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380
Hypertension in Childhood Nephrotic Syndrome
منشور في 2019"…Others are associated with chronic and more sustained HTN such as renal fibrosis, decreased GFR, and progression of chronic kidney disease. …"