The Economic Impact of Optimizing a COVID-19 Management Protocol in Pre-Existing Cardiovascular Disease Patients by Dina Abushanab (10696501)

“…<p>This study answers the question of whether the health care costs of managing COVID-19 in preexisting cardiovascular diseases (CVD) patients increased or decreased as a consequence of evidence-based efforts to optimize the initial COVID-19 management protocol in a CVD group of patients. …”

Solar Technology and District Cooling System in a Hot Climate Regions: Optimal Configuration and Technology Selection by Rabah Ismaen (18387189)

“…The PVT-DCS configuration has the lowest operation cost and the highest environmental performance by decreasing the global warming potential by 89.5%. The T-DCS configuration becomes economically competitive only at high electricity tariffs.…”

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman Alzu'bi (18192898)

“…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”

Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders by Jaunetta Hill (18255631)

“…Specific levels of SP1-driven genes and AD biomarkers such as amyloid precursor protein (APP) and Tau proteins were also decreased as part of this targeted systemic response. …”

Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice by Tomas Venit (17248420)

“…These changes are associated with reduced OXPHOS gene expression, decreased mitochondrial DNA copy number, and deregulated mitochondrial dynamics, which lead to metabolic reprogramming of NM1 KO cells from OXPHOS to aerobic glycolysis.This, in turn, is associated with a metabolomic profile typical for cancer cells, namely increased amino acid-, fatty acid-, and sugar metabolism, and increased glucose uptake, lactate production, and intracellular acidity. …”

Sulfobetaine-based polydisulfides with tunable upper critical solution temperature (UCST) in water alcohols mixture, depolymerization kinetics and surface wettability by Jozef Kollár (8121347)

“…Tunable surface wettability were shown on the grafted polymers. Findings: Decreasing polarity and/or increasing alcohol percentage in the water mixtures induced an increase in the cloud points of the polymers in the solutions. …”

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss by Meritxell Espino Guarch (18810097)

“…Thus, a screening of a cohort of ARHL patients and controls was carried out revealing several variants inSLC7A8, whose role was further investigated by in vitro functional studies. Significant decreases in SLC7A8 transport activity was detected for patient’s variants (p.Val302Ile, p.Arg418His, p.Thr402Met and p.Val460Glu) further supporting a causative role for SLC7A8 in ARHL. …”

Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease by Satra Nim (11540447)

“…Conversely, the peptide inhibitor restores endolysosomal function and thereby decreases α-synuclein levels in multiple models, including female and male human cells harboring disease-causing α-synuclein mutations. …”

Fixing a heart valve by Nature Research (16552612)

“…As Antune points out, however, the proportion of repaired valves that need to be replaced later on decreases with surgeons' increasing experience of the procedure. …”

Novel polysulfone ultrafiltration membranes incorporating polydopamine functionalized graphene oxide with enhanced flux and fouling resistance by Abedalkader Alkhouzaam (15842647)

“…Thus, the pure water flux increased with the addition of rGO-PDA without affecting the rejection properties, while the flux decreased with the embedding of pristine GO particles. …”

Anabolic steroids-induced delirium by Mohamed Adil Shah Khoodoruth (14589828)

“…Laboratory results showed a decreased plasma testosterone level of 9.59 nmol/l (10.4–37.4 nmol/l). …”

Post-transcriptional regulation of Pabpn1 by the RNA binding protein HuR by Brittany L Phillips (18696937)

“…We exploit multiple models including C2C12 myotubes, primary muscle cells, and mice to determine that HuR decreases Pabpn1 expression. Overall, we have uncovered a mechanism in mature muscle that negatively regulates Pabpn1 expression in vitro and in vivo, which could provide insight to future studies investigating therapeutic strategies for OPMD treatment.…”

Enhancing the corrosion resistance of reinforcing steel under aggressive operational conditions using behentrimonium chloride by A. Bahgat Radwan (9631720)

“…In conclusion, this new inhibitor shows high corrosion inhibition efficiencies under different aggressive conditions and can be used in concrete to reduce the corrosion rate of reinforcing steel without decreasing the mechanical properties of the concrete.…”

Life cycle assessment of binary recycled ceramic tile and recycled brick waste-based geopolymers by Namra Mir (17017734)

“…The LCA analysis is also modelled on a large-scale industrial basis. This results in decreased environmental impacts, and they are 1352 kg CO₂-eq, 3.01 kg SO₂-eq, 0.19 kg N-eq, 6.56E-9 kg CFC 1-eq for GWP, AP, EP, and ODP, respectively.…”

Driving and hypoglycemia by Stephen Beer (5480411)

“…Hypoglycemia has been associated with cardiac arrhythmia, a decreased ability to drive and driving mishap. Recent meta-analysis of 15 studies showed a risk road traffic collisions (RTC) of 12-19% greater than general populations. …”

A Power Ripple Compensator for DC Nanogrids via a Solid-State Converter by Ahmad Khan (6067526)

“…<h3>Abstract</h3><p dir="ltr">This paper presents a method for improving the reliability of DC nanogrids by decreasing the input capacitance requirement. The nanogrid DC bus capacitance requirement is reduced by utilizing the zero-sequence operation mode of the solid state converter (SSC). …”

Non-Isolated DC–DC Power Converter With High Gain and Inverting Capability by Mohammad Meraj (16855401)

“…To reduce the ripple in the input current with simultaneous decreasing the input current ripple, a novel current fed interleaved high gain converter is proposed by utilizing the interleaved front-end structure and Cockcroft Walton (CW)-Voltage Multiplier (VM). …”

Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings by M.S. Khan (22047413)

“…<p>The impact of corrosion is widespread, affecting structures, equipment, and infrastructure across various industries increasing the maintenance cost and thereby decreasing profit and efficiency. Nickel-based coatings are one of the most tempting options owing to their enhanced mechanical and corrosion-resistant properties. …”

Vertical Distribution of Phosphorous Fractions and Bioavailability of the Nutrient in the Southern Indian Ocean by Muhammed Nayeem Mullungal (21385463)

“…The lower iron bound P fraction at specific depths was attributed to the nature of Fe minerals present within sediments. Decreased level of organic phosphate fraction was due to mineralization. …”

Assessing the Electricity Production Capacities of Emerging Markets for the Sustainable Investments by Tamer Aksoy (17947802)

“…First, it would be appropriate to provide tax exemptions to solar energy investors so that the costs of these projects can be decreased. Additionally, investments in solar energy technologies need to be further increased.…”