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41
Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
Published 2021“…<p dir="ltr">Diabetes-associated long-term hyperglycaemia leads to oxidative stress-mediated fibrosis in different tissues and organs. …”
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Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue
Published 2014“…<p dir="ltr">Obesity is characterized by a chronic low-grade inflammation and altered stress responses in key metabolic tissues. Impairment of heat shock response (HSR) has been already linked to diabetes and insulin resistance as reflected by decrease in heat shock proteins (HSPs) expression. …”
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43
Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese
Published 2018“…<p dir="ltr">Heat shock protein 60 (HSP60) is a key protein in the crosstalk between cellular stress and inflammation. However, the status of HSP60 in diabetes and obesity is unclear. …”
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Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens
Published 2021“…<p dir="ltr">Ochratoxin A (OTA), an important fungal metabolite in foods and feeds has been shown to induce oxidative stress and cellular injuries to human and animal subjects. …”
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45
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
Published 2019“…We assessed if increased MG glycation induced proteotoxic stress, identifying related metabolic drivers and protein targets. …”
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46
Numerical Investigation of the Fetal Left Heart Hemodynamics During Gestational Stages
Published 2021“…This maximum WSS decreases to 11 Pa at the gestational week of 27, indicating nearly three-times reduction in the peak shear stress. …”
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47
A new perspective on cardiovascular drift during prolonged exercise
Published 2021“…<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. …”
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48
Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover
Published 2020“…We consider dicarbonyl stress, the functional vulnerability of the plant proteome to arginine-directed glycation and the likely role of methylglyoxal-mediated glycation in the activation of the unfolded protein response in plants. …”
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49
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic stress. Restoring the normal expression of DNAJB3 attenuated metabolic stress and improved insulin signaling both in vivo and in vitro, suggesting a protective role of DNAJB3 against obesity and T2D. …”
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Designing a Carbon Utilization Network: From Stationary Sources to Agricultural Greenhouses
Published 2025“…Economically, this approach can reduce operational costs, stimulate local agricultural sectors, and decrease reliance on food imports, fostering resilience against global market fluctuations. …”
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Coping strategies, optimism, and resilience factors associated with mental health outcomes among medical residents exposed to coronavirus disease 2019 in Qatar
Published 2023“…<p> </p> <h2>Objective</h2> <p>The aim of this study is to examine the association between coping strategies, resilience, optimism and different mental health outcomes like stress, anxiety, and depression among the medical residents’ during the COVID-19 pandemic, with consideration of different factors like seniority, frontliner, gender, and coping style.…”
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54
Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes
Published 2019“…These altered identities of β cells likely serve as a compensatory response to enhance function/expand cell numbers and may also camouflage/protect cells from ongoing stress. …”
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Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study
Published 2025“…There was a significant decrease in the trend of geriatric trauma over the years. …”
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56
A potential therapeutic agent for sickle cell anaemia
Published 2016“…</p><p>A team of researchers in Basra in southern Iraq studied 42 patients with sickle cell anaemia and found evidence of alterations in the levels of oxidative stress markers, indicating oxidative stress. They also found increased levels of ROS that were associated with decreased levels of antioxidant enzymes and their co-factors.…”
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Disrupted harvests: how Ukraine – Russia war influences global food systems – a systematic review
Published 2024“…Utilizing a rigourous methodology, we screened 236 articles from the Web of Science database as of March 2023, narrowing the corpus to 62 significant publications that meet comprehensive eligibility criteria. The war affected all food security dimensions, but the most dramatic impact was on food access. …”
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
Published 2021“…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …”
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59
Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
Published 2023“…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …”
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A Comprehensive Assessment of an Autonomous Electric Vehicle Fast Charging Station with Multiple Renewables and Energy Storage Systems
Published 2022“…<p dir="ltr">E-mobility has become of great interest for many countries worldwide, where the main objective is to decrease the dependency on fossil fuel-based transportation means and reduce CO<sub>2</sub> emissions generated from the transportation sector. …”