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Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload
منشور في 2024"…<p>Glucagon-like peptide-1 (GLP-1) agonists and GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) co-agonists are major treatment options for subjects with obesity and patients with type 2 diabetes mellitus (T2DM). …"
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Exploring beyond numeric weight loss: The metabolic effects of semaglutide
منشور في 2025"…Furthermore, semaglutide was the only effective Glucagon Like Peptide-1 Receptor Agonist in reducing Low-Density Lipoprotein and total cholesterol levels, with mean differences of −0.16 mmol/L and −0.48 mmol/L, respectively. …"
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Functional fatigue of Ni50.3Ti25Hf24.7 - Heterogeneities and evolution of local transformation strains
منشور في 2017"…Shape memory alloys achieve their unique and desirable property of large recoverable strains through phase transformation. …"
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Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
منشور في 2024"…These findings were found to be correlated with increased level of <u>oxidative stress, neuroinflammation,</u> and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating <u>synaptic plasticity</u> integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …"
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Enhancing Security and Performance in Live VM Migration: A Machine Learning‐Driven Framework With Selective Encryption for Enhanced Security and Performance in Cloud Computing Envi...
منشور في 2025"…However, concerns persist regarding safeguarding sensitive data during migration, particularly in critical sectors like healthcare, banking and military operations. …"
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Crystallization properties of arsenic doped GST alloys
منشور في 2019"…<p dir="ltr">We present the enhanced properties observed in the phase change memory alloy Ge<sub>2</sub>Sb<sub>2</sub>Te<sub>5</sub> (GST) when doped with arsenic. …"
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Machine Learning-Based Management of Electric Vehicles Charging: Towards Highly-Dispersed Fast Chargers
منشور في 2020"…<p dir="ltr">Coordinated charging of electric vehicles (EVs) improves the overall efficiency of the power grid as it avoids distribution system overloads, increases power quality, and decreases voltage fluctuations. Moreover, the coordinated charging supports flattening the load profile. …"
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Daucus Carota oil extract, a chemotherapeutic agent, acts as an antidepressant that promotes resilience to chronic social defeat stress
منشور في 2021"…A decrease in the hippocampal p-Akt protein levels is observed in depressed subjects. …"
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A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies
منشور في 2022"…In order to interpret the experimental results and give right diagnostics behind the decrease of the current through the junction after electron irradiation, we supplement the experiment with quantum transport calculations using Green's functional formalism in combination with density functional theory. …"
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The Role of KM in Enhancing AI Algorithms and Systems
منشور في 2020"…The main finding of the research was the massive impact of some KM processes like knowledge acquisition and knowledge creation on the different types of AI systems and algorithms to give an additional option for organizations during the implementation. …"
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Effect of anions on the structural, morphological and dielectric properties of hydrothermally synthesized hydroxyapatite nanoparticles
منشور في 2019"…The εʹ and dielectric loss (εʹʹ) values for the HA nanoparticles decrease with increase in the applied frequency as well. …"
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Rescue cerclage
منشور في 2006"…Women who required rescue cerclage after failed prophylactic cerclage (n = 12) were 50% less likely to reach 28 weeks. Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. …"
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A framework for implementing Green Supply Chain Management: The Case of Petco Gulf
منشور في 2021"…From this research, it was found that as Petco gulf is present in the U.A.E. it can take advantage of this and by applying the GSCM strategies against each of its components this will help the company by, increased overall gross profit with the decrease in cost since going green in its supply chain means reducing the overheads. …"
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Self-reported awareness and attitude of cancer patients towards clinical nurse coordinators
منشور في 2017"…Background and objective: Lack of knowledge or poor perception towards the roles and responsibilities of clinical nurse coordinators among cancer patients might lead to a decrease in seeking their services. The objective of the study was to assess the knowledge, perception and attitude towards clinical nurse coordinators among cancer patients at a specialized cancer center in Jordan. …"
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1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH
منشور في 2010"…In the Phase I study, mean IPSS showed a decrease of 6.5 points (34%), mean QoL a decrease of 2 points (44%) and mean prostate volume a decrease of 5.5 cc (13%) at 12-months compared to screening. …"
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