From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease حسب Ahmad Raza (18205961)

"…This review focuses on the potential mechanisms associated with these two diseases, like insulin resistance, inflammation, oxidative damage, mitochondrial injury, and cell death. …"

Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar حسب Shuja Mohd Reagu (12051406)

"…Breastfeeding requires close physical contact and observance of hygienic measures like handwashing. Worries around contamination increase during the perinatal period and can be expressed as increase in obsessive compulsive symptoms. …"

Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery حسب Stephen L. Atkin (6684368)

"…</p><p dir="ltr"><br></p><h3>Methods: </h3><p dir="ltr">Twenty-nine type 2 patients with severe obesity (mean BMI 46.2 kg/m²) and diabetes underwent Roux-en-Y gastric bypass (RYGB) surgery. …"

The effect of microbiome therapy on COVID-19-induced gut dysbiosis: A narrative and systematic review حسب Mahmoud Yousef (9900837)

"…Further, bidirectional communication between the gastrointestinal tract and vital organs like the lung, heart, brain, and liver can exacerbate the disease severity and cause further inflammation and dysbiosis. …"

Novel proteins implicated in lipid metabolism disorders حسب Nature Research (16552612)

"…After feeding, its expression is decreased, promoting the uptake of dietary lipids in fat tissue. …"

Biomarkers show promise for treatment of heart valve disease حسب Nature Research (16552612)

"…They are also comparing the levels of valve tissue markers with microRNAs and toll-like receptors, proteins involved in the immune system, in experimentally produced aortic stenosis in rabbits.…"

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... حسب Samar Shurbaji (9938696)

"…Most of these TSH-LFIAs are designed for qualitative measurements (i.e., if TSH values > 5, or >15 IU/L) and as screening tests for primary hypothyroidism in children and adults. …"

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…<p dir="ltr">Dysregulated epigenetic modifications are common in lung cancer but have been reversed using demethylating agent like 5-Aza-CdR. 5-Aza-CdR induces/upregulates the NY-ESO-1 antigen in lung cancer. …"

Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 حسب Fiona B, Bennitt

"…We first estimated the mean fuel type-specific concentrations (in μg/m3) of fine particulate matter (PM2·5) pollution to which individuals using solid fuels for cooking were exposed, categorised by fuel type, location, year, age, and sex. …"
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... حسب Michael, Brauer

"…Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2·5th and 97·5th percentile values across the draws. …"
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Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 حسب Austin, Carter

"…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …"
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Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Joseph L Ward (9715619)

"…Furthermore, indirect effects of the COVID-19 pandemic are likely to jeopardise efforts to improve health outcomes including mortality in young people aged 10–24 years. …"

Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity حسب Imran Ramzan (15430807)

"…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …"

A Case Study in Qatar for Optimal Energy Management of an Autonomous Electric Vehicle Fast Charging Station with Multiple Renewable Energy and Storage Systems حسب Abdulla Al Wahedi (17115613)

"…This interest has focused mainly on reducing the reliance on fossil fuel-based means of transportation and decreasing the harmful emissions produced from this sector. …"

Driving against the clock: Investigating the impacts of time pressure on taxi and non-professional drivers’ safety and compliance حسب Qinaat Hussain (15294164)

"…<p>Drivers often encounter time pressure, which can lead to riskier driving habits, decreased safety margins, and a higher chance of accidents. …"

Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas حسب Abu Saleh Md Moin (6189512)

"…<h3>Context: </h3><p dir="ltr">Previously, we identified chromograninA positive hormone-negative (CPHN) cells in high frequency in human fetal and neonatal pancreas, likely representing nascent endocrine precursor cells. …"

Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis حسب HASHEM ABU SERHAN (19737499)

"…In vitrectomized eyes, notable decreases were observed: at 30 min, the Ratio of Means (ROM) was 0.81 (95% CI: 0.53; 1.24), indicating a 19% reduction; at 60 min, the ROM of 0.833 (95% CI: 0.77; 0.89) showed a 16.7% reduction; at 90 min, the ROM of 0.757 (95% CI: 0.755; 0.758) corresponded to a 24.3% reduction; at 2 h, the ROM of 0.726 (95% CI: 0.642; 0.820) reflected a 27.4% reduction; at 3 h, the ROM of 0.692 (95% CI: 0.600; 0.797) resulted in a 30.8% reduction; and at 4 h, the ROM of 0.700 (95% CI: 0.363; 1.350) indicated a 30% reduction. …"

Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas حسب Tejedor, Alejandro

"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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Dynamic Properties of Water Confined in Graphene-Based Membrane: A Classical Molecular Dynamics Simulation Study حسب One-Sun Lee (1291293)

"…We believe that our simulation results would be a significant contribution for designing a new graphene-based membrane for desalination.…"

Preterm birth in low-middle income Countries حسب Alim, Swarray-Deen

"…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …"
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