Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitness in US Adults by Vijay Ganji (8710491)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”

Influence of temperature on tire-pavement noise in hot climates: Qatar case by Okan, Sirin

“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
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Innovative strategies to reduce traffic related injuries and deaths in youth by Joanne Banfield (19794507)

“…(Prevent Alcohol and Risk-Related Trauma in Youth) Program is one of those programs. …”

The Effect of Number of Corrugation on Crashworthiness of Aluminum Corrugated Tube under Lateral Loading by Hozhabr Mozafari (18891892)

“…The results show that tubes with corrugations have a higher mean crushing force which is directly proportional to the number of corrugations. …”

Impact of severe hypoglycemia on the heat shock and related protein response by Alexander S. Atkin (18520107)

“…Our hypothesis was that hypoglycemia-induced heat shock and related protein changes would be amplified in type 2 diabetes (T2D). …”

Epidemiological and clinical characteristics of fall-related injuries: a retrospective study by Ahammed Mekkodathil (4578838)

“…Although the rate of fall-related injuries decreased over the years, the average number of patients per year remained high accounting for 32% of the hospitalized patients with moderate to severe injuries. …”

The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i> by Safa Salim (9186786)

“…<p dir="ltr">1p32.3 microdeletion/duplication is implicated in many neurodevelopmental disorders-like phenotypes such as developmental delay, intellectual disability, autism, macro/microcephaly, and dysmorphic features. …”

Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. by Sara, Sokary

“…Studies have shown that semaglutide reduced fat mass, particularly visceral fat, while preserving lean muscle mass, as the proportion relative to total body mass decreased by 3.5% and 2.0% for total and visceral fat mass, respectively, while it increased by 3.0% for lean body mass. …”
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Influence of temperature on tire-pavement noise in hot climates: Qatar case by Okan Sirin (14603304)

“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”

Effect of Hypoxia on Muscle Activation During Incremental Exercise at Equivalent Relative Intensity by Dania Nazeeh Ibrahim (21547487)

“…The RCP was the benchmark for determining the relative intensity in the step tests among two conditions. …”

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension by Thiruveni Ramkumar (17075051)

“…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …”

Heat Shock-Related Protein Responses and Inflammatory Protein Changes Are Associated with Mild Prolonged Hypoglycemia by Abu Saleh Md Moin (6189512)

“…At hypoglycemia, UBE2N, STIP1, and UBE2L3 increased (all p < 0.05), whilst TLR4:MD-2 and HSPA8 decreased (p < 0.05) in T2D versus baseline. In follow-up after hypoglycemia, HSPs normalized to baseline by 24 h, except UBE2L3 (p < 0.05), which was decreased in controls versus baseline. …”

Rising mortality related to cardiovascular disease and prostate cancer amongst older men across the United States by Abdul Ahad (545575)

Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload by Naila Rabbani (291722)

“…<p>Glucagon-like peptide-1 (GLP-1) agonists and GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) co-agonists are major treatment options for subjects with obesity and patients with type 2 diabetes mellitus (T2DM). …”

Never out of Now: Preference Falsification, Social Capital and the Arab Spring by Ammar Shamaileh (5678516)

A Sociodemographic Analysis of the Impact of COVID-19-Related Schools’ Closure on the Diet and Physical Activity of Children and Adolescents in Qatar by Muna Abed Alah (14779534)

“…<h3>Objectives</h3><p dir="ltr">To assess the impact of the COVID-19-related closure of government schools in Qatar on children and adolescents' dietary habits and physical activities and associated sociodemographic factors.…”