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401
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
منشور في 2013"…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…"
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article -
402
PSA-activated proaerolysin as a prostate specific cancer therapy
منشور في 2006"…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …"
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conferenceObject -
403
The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013)
منشور في 2016"…In this study, we aim to determine a possible mechanism of action of kefir and to study its effect on the motility of colorectal and breast cancer cell lines. Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …"
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masterThesis -
404
Hardware Trojan Mitigation Technique in Network-on-Chip (NoC)
منشور في 2023"…The proposed method increases the number of received packets by up to 10% more compared to existing techniques, which contain HTs in the destination address of the flit. …"
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405
Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer c...
منشور في 2024"…F6 decreased MDA-MB-231 viability more than crude ZNE or its other fractions. …"
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406
ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder
منشور في 2017"…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …"
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407
Comparison of Pulmonary Complications after Nonmyeloablative and Conventional Allogeneic Hematopoietic Cell Transplant
منشور في 2012"…It is not known whether the decreased tissue injury associated with nonmyeloablative conditioning lowers the risk of pulmonary complications. …"
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408
Effectiveness and specificity of a classroom-based group intervention in children and adolescents exposed to war in Lebanon
منشور في 2008"…The rates of disorders peaked one month post-war and decreased over one year. There was no significant effect of the intervention on the rates of MDD, SAD or PTSD. …"
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409
Phosphorus supplement alters postprandial lipemia of healthy male subjects
منشور في 2014"…Concurrently, phosphorus supplementation increased postprandial concentrations of apolipoprotein B48 (ApoB48) (p < 0.05) and decreased that of apolipoprotein B100 (ApoB100) (p < 0.05). …"
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410
Comparison of pulmonary complications after nonmyeloablative and conventional allogeneic hematopoietic cell transplant
منشور في 2012"…It is not known whether the decreased tissue injury associated with nonmyeloablative conditioning lowers the risk of pulmonary complications. …"
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article -
411
The impact of bank liquidity on the Lebanese banks’ risk taking behavior
منشور في 2018"…This conclusion might suggest that higher capital requirements under Basel III are likely to increase bank risk with the implementation of new liquidity ratio. …"
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article -
412
Light chain amyloidosis presenting with autoimmune hepatitis-primary sclerosing cholangitis overlap syndrome
منشور في 2020"…</p><h3>Interventions</h3><p dir="ltr">The patient received Ursodeoxycholic acid for pruritis. Magnetic resonance cholangiopancreatography was done to diagnose PSC. …"
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413
Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
منشور في 2020"…Males were predominant (89%), more likely to fall at workplace, fall from a greater height and have polytrauma than females. …"
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414
CRISPR-Cas Controls Cryptic Prophages
منشور في 2022"…Specifically, compared to the wild-type strain, reducing the amounts of specific interfering RNAs (crRNA) decreases growth by 40%, increases cell death by 700%, and prevents persister cell resuscitation. …"
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415
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
منشور في 2023"…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …"
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416
Preterm birth in low-middle income Countries
منشور في 2024"…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …"
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article -
417
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418
Geomorphological changes in the coastal area of Farasan Al-Kabir Island (Saudi Arabia) since mid Holocene based on a multi-proxy approach
منشور في 2018"…The mid Holocene evolution of the borehole area is resulted from the detailed analysis of five sedimentary units detected along the core Matar-1, and includes three distinct stages: (a) from 5253 ± 223 y cal BP to 3138 ± 223 y cal BP, carbonate coarse-grained material consisting of coral fragments, molluscs, calcareous algae and benthic foraminifera are deposited on a shallow marine fringing reefal platform, which becomes progressively a nearshore backreef (around 3675 ± 215 y cal BP), and later (around 3138 ± 223 y cal BP) a reef ramp; (b) since 3040 ± 220 y cal BP the borehole area obtains the characteristics of a high-energy beach that receives increasing inputs of terrigenous material; (c) subsequently, a supratidal backshore setting is established influenced mostly by terrestrial processes and occasionally by marine processes, as it is indicated by the decreasing and sometimes sporadic presence of benthic foraminifera, and recently, a sedimentary veneer consisting of terrigenous, carbonate and evaporite material is formed by terrestrial, mainly wadi and aeolian, processes. © 2018 Elsevier Ltd and INQUA…"
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419
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
منشور في 2022"…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …"
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420
A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion
منشور في 2023"…The limited requests for retribution are likely due to a sense of impunity and adaptation to cumulative trauma. …"
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article