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41
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent
Published 2019“…Addition of excess L-citrulline rescued only one of three cell lines tested, indicating that the majority of cell lines are completely auxotrophic for arginine. …”
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. Sensitivity to arginine depletion using HuArgI (Co)-PEG5000 was evident in all of the tested PC cell lines with IC50 values in the pM range at 72 hours following treatment. …”
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Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells
Published 2015“…Upon treatment, a pronounced decrease in cancer cell motility was observed in the 4 cell lines. …”
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Improving Emergency Response Communication In Race Circuits
Published 2011“…As a fact, the use of communication over radio connection (walkie-talkie) makes great challenge in interpreting reports sent by responders since the noise and different accents in responders’ crews, which might encounter great threat and delay in response time.Furthermore, cameras blind spots and angles might decrease the certainty of the incident scene. In contrast, the proposed emergency response communication system deploys wireless network aside with handheld devices and all other circuit technologies to send or receive instant messages between the control unit and the responders. …”
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48
The antioxidant and anticancer effects of Wild Carrot oil extract
Published 2012“…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …”
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The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013)
Published 2013“…Upon treatment, a pronounced decrease in cancer cell motility was observed in the four cell lines used. …”
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50
The role of job description as a motivational tool. (c2000)
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51
An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im...
Published 2020“…In terms of United Arab Emirates University (UAEU), there has been a decrease in STEM programs enrolment, while STEM graduates in UAEU has stayed steady at 1/3 STEM majors compared to 2/3 non-STEM programs. …”
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Cryomyolysis, a new procedure for the conservative treatment of uterine fibroids
Published 1998“…Normal uterine volume ranged from 35.6 to 548.7 ml preoperatively and 45.1 to 729.6 ml postoperatively (mean increase 40%); however, myoma volume showed a mean decrease of 6% (range-87-28%). …”
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Recent advances in the treatment and outcome of locally advanced rectal cancer
Published 1999“…Of those receiving any pre- or postoperative chemotherapy, three patients received chemotherapy in the early era, compared with 76 in the late era. …”
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Empiric antibiotic therapy of community-acquired Pneumonia at the American University of Beirut Medical Center. (c2001)
Published 2001“…Special attention should be given to decrease hospitalization rate, to preserve fluoroquinolones, and to improve microbiological studies outcome.…”
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55
Is board compensation excessive?
Published 2017“…For companies that overpay, the average excess compensation is greater than $60,000 per director, while directors that are underpaid receive about $33,000 less than predicted. Excess compensation declines over our sample period, which may be consistent with increased director workloads as well as increased scrutiny. …”
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Daucus Carota oil extract, a chemotherapeutic agent, acts as an antidepressant that promotes resilience to chronic social defeat stress
Published 2021“…A decrease in the hippocampal p-Akt protein levels is observed in depressed subjects. …”
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57
Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study
Published 2025“…There was a significant decrease in the trend of geriatric trauma over the years. …”
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
Published 2021“…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …”
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Breast cancer cells and bone marrow mesenchymal stromal cells
Published 2017“…Co-cultures with either MG-63 cells or MSCs induced OPG and MMP-2 in both tumor cell lines. Interestingly, conditioned medium from co-cultures of MSCs and MDA-MB-231 cells significantly decreased the proliferation of activated T lymphocytes which was reversed by addition of anti-OPG antibodies to the co-cultures. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …”
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