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441
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
منشور في 2014"…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …"
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article -
442
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
منشور في 2011"…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …"
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article -
443
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
منشور في 2013"…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…"
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article -
444
Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation
منشور في 2008"…Results: Twelve eyes (92.3%) had stable or improved BCVA, and 8 eyes (61.5%) had at least 2 lines of vision improvement. The average BCVA improved from 20/203 at baseline to 20/113 at 12 weeks (P = 0.001). …"
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article -
445
PSA-activated proaerolysin as a prostate specific cancer therapy
منشور في 2006"…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …"
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conferenceObject -
446
The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013)
منشور في 2016"…In this study, we aim to determine a possible mechanism of action of kefir and to study its effect on the motility of colorectal and breast cancer cell lines. Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …"
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masterThesis -
447
Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer c...
منشور في 2024"…F6 decreased MDA-MB-231 viability more than crude ZNE or its other fractions. …"
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448
Effects of financial turmoil on financial integration and risk premia in emerging markets
منشور في 2016"…We find that while the financial integration of emerging stock markets has registered short-term reversals episodes in countries that have been exposed to national or/and regional financial crises, it has decreased in most of the emerging countries of our sample since the global crisis. …"
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449
ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder
منشور في 2017"…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …"
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450
The role of market-based transformative service initiatives in service inclusion of refugees
منشور في 2023"…Moreover, focusing on the refugee crisis in the Middle East region is rather understudied in the service research literature.…"
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article -
451
Driving and hypoglycemia
منشور في 2015"…<p dir="ltr">Qatar is one of the 20 countries of the IDF MENA region. Three hundred and eighty seven million people have diabetes worldwide and more than 37 million people in the MENA Region; by 2035 this will rise to 68 million. …"
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452
Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
منشور في 2024"…Increasing symptomatic treatment coverage among FSWs from 0 % to 100 % decreases prevalence from 10.6 % to 4.5 %, 0.8 % to 0.4 %, and 0.3 % to 0.1 %, respectively. …"
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article -
453
The impact of bank liquidity on the Lebanese banks’ risk taking behavior
منشور في 2018"…This conclusion might suggest that higher capital requirements under Basel III are likely to increase bank risk with the implementation of new liquidity ratio. …"
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article -
454
Hedonic valuation of land protection methods: implications for cluster development.
منشور في 2014"…The empirical framework accounts for topographical diversity across the study region, as well as distinguishing between several distinct types of publicly and privately protected land. …"
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article -
455
Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
منشور في 2020"…Males were predominant (89%), more likely to fall at workplace, fall from a greater height and have polytrauma than females. …"
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456
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
منشور في 2023"…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …"
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457
Preterm birth in low-middle income Countries
منشور في 2024"…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …"
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article -
458
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
منشور في 2022"…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …"
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459
A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion
منشور في 2023"…The limited requests for retribution are likely due to a sense of impunity and adaptation to cumulative trauma. …"
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article -
460
Evaluation of transportation network reliability during unexpected events with multiple uncertainties
منشور في 2016"…These uncertainties are likely due to the effect of natural disasters on road networks. …"
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article