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381
Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats
منشور في 2017"…Here, we investigated the effects of exendin-4 or selenium administration on the expression of glucagon-like peptide-1 receptor (GLP-1R), insulin receptor substrate-1 (IRS-1), and preproinsulin in the pancreas of diabetic rats. …"
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article -
382
Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration
منشور في 2009"…Inflammation and Parkinson’s-like lesions induced by MPTP intoxication could lead to modification of drug pharmacokinetics and have clinical consequences, such as neurotoxicity.…"
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article -
383
An additive manufacturing approach based on electrohydrodynamic printing to fabricate P3HT:PCBM thin films
منشور في 2023"…The EHDA printed thin-film’s topography, morphology and optical properties were systematically analyzed. The root-mean-square roughness was found to vary significantly with the annealing temperature and the flow rate and ranged from 1.938 to 3.345 nm. …"
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384
Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases
منشور في 2024"…</p><h3>Results</h3><p dir="ltr">Among 8200 cholecystectomies, 60 cases of MS were identified, with type 1 being the most prevalent (90%). The mean age of the patients was 44 years, with male predominance (75%). …"
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385
Efficient multi-objective neural architecture search framework via policy gradient algorithm
منشور في 2024"…However, differentiable NAS methods encounter challenges when dealing with non-differentiable objectives like energy efficiency, resource constraints, and other non-differentiable metrics, especially under multi-objective search scenarios. …"
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386
Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant
منشور في 2022"…The graphical simulations are performed for flow parameters with specific range like 1≤Re≤5, 1≤Ha≤5, 0.5≤Nt≤2.5, 1≤Nb≤3, 0.2≤Sc≤1.8, 0.2≤Pe≤1.0 and 0.2≤Ω≤1.0. …"
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387
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
منشور في 2018"…The addition of chloroquine, an autophagy inhibitor, increased the sensitivity of cells to [HuArgI (Co)-PEG5000]-mediated arginine depletion at earlier time points. We also concluded that autophagy was activated in response to arginine depletion and plays a protective role at early time points. …"
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masterThesis -
388
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
منشور في 2017"…We have established that autophagy, a process of cellular destruction activated in response to arginine deprivation, can be the leading cause of cell death at late drug incubation times. Hence, our study demonstrates that HuArgI (Co)-PEG5000 is a novel, potent and selective potential therapeutic approach for PC.…"
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masterThesis -
389
Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
منشور في 2018"…SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …"
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390
Impact of the COVID-19 lockdown on lifestyle behaviors and their association with personality among adults in Qatar: A cross-sectional study
منشور في 2022"…The overall MD adherence decreased during lockdown (5.9 vs. 6.1, p < 0.001). …"
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391
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
منشور في 2020"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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392
Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas...
منشور في 2021"…Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. …"
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393
Supplementation of retrobulbar block with clonidine in vitreoretinal surgery
منشور في 2011"…Conclusions The addition of clonidine 0.5 μg/kg to the local anesthetics of a retrobulbar block for vitreoretinal surgery decreases the frequency of postoperative pain and prolongs the time of analgesia.…"
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article -
394
Influence of co-current vapor flow on falling film over horizontal tube
منشور في 2021"…First, the liquid load is varied between 0.02 and 0.05 kg/(m·s), and its effects on the film thickness and the wetting time are calculated, presented and discussed. Afterwards, the impact of co-current vapor flow on film distribution, wetting time, minimum thickness and its location are quantified and examined by increasing the vapor velocity up to 6 m/s with 2 m/s intervals. …"
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395
Sustainable Detoxification of Methylene Blue in Wastewater via Tea Residue Adsorption: Optimization and Kinetics
منشور في 2025"…The impact of various parameters on MB removal was assessed, including solution pH, adsorbent dosage, pollutant concentration, and contact time. Optimal conditions were identified as pH 10, a dosage of 4 g/L, a concentration of 100 mg/L, and a contact time of 2 h, achieving nearly 99% removal efficiency at 25 °C. …"
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396
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397
Throughput of ARQ protocols over Rician, Nakagami and MIMO block fading channels
منشور في 2020"…Keywords: ARQ, throughput, error probability, fading channels, space-time, multiple antennas, transmit diversity, MIMO, Rician, Nakagami.…"
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article -
398
Biomarkers show promise for treatment of heart valve disease
منشور في 2015"…The researchers suggest that patients with increased pro- or decreased anti-calcific factors in their serum should avoid replacement with a bioprosthesis. …"
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399
Business Continuity Management Maturity Model for Banks in UAE
منشور في 2008"…They are faced with increasing levels of global competition, demanding customers and employees, shrinking product lifecycles and decreasing acceptable response times (Lockamy & McCormack, 2004) They have employees and deal with clients, suppliers & vendors from all over the world. …"
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400