In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation by Sleiman, Sama F.

“…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…”
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Conflicts Employee-Employee by Al Ali, Fatma Jasim

“…"Conflict" likes water and fire can be good or bad. Conflict is good when it is constructive and bad when it is destructive. …”
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Thermodynamic analysis of solar-driven integrated system for efficient brine management and hydrogen production by Nadira Salsabila (16855101)

“…Rejected brine from the RO process is treated using reverse electrodialysis (RED) and the photo-chloralkali (PCA) process to produce valuable chemicals, including hydrogen, which is converted into electricity using a proton exchange membrane (PEM) fuel cell. …”

Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells by Ejlal Abu-El-Rub (5168183)

“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”

The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties by Jelena Eric (21015107)

“…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …”

Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy by Jia-Zhen Wu (6844793)

“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”

The impact of bank liquidity on the Lebanese banks’ risk taking behavior by El Khoury, Rim

“…This conclusion might suggest that higher capital requirements under Basel III are likely to increase bank risk with the implementation of new liquidity ratio. …”
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Effectiveness and specificity of a classroom-based group intervention in children and adolescents exposed to war in Lebanon by Dimassi, Hani

“…The rates of disorders peaked one month post-war and decreased over one year. There was no significant effect of the intervention on the rates of MDD, SAD or PTSD. …”
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Effect of structural remodeling (retraction and recoil) of the pipeline embolization device on aneurysm occlusion rate by Jou, L.-D.

“…On average, it increases its diameter by 0.23 mm and decreases its length by 2.88 mm within 6 months of initial deployment. …”
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Epidemiological and clinical characteristics of fall-related injuries: a retrospective study by Ahammed Mekkodathil (4578838)

“…Males were predominant (89%), more likely to fall at workplace, fall from a greater height and have polytrauma than females. …”

CRISPR-Cas Controls Cryptic Prophages by Sooyeon Song (4891132)

“…Specifically, compared to the wild-type strain, reducing the amounts of specific interfering RNAs (crRNA) decreases growth by 40%, increases cell death by 700%, and prevents persister cell resuscitation. …”

STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration by Ayat S. Hammad (9592374)

“…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …”

Preterm birth in low-middle income Countries by Alim, Swarray-Deen

“…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …”
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Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF by Jabr, Vanessa

“…Interestingly, we also found that inhibition of autophagy in exercising 10-week-old mice decreases BDNF protein levels in the hippocampus as compared to the control exercising group. …”
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RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells by El Atat, Oula

“…While knocking down either RHO, GTPase did not affect p-AKT levels, and p-ERK decreased in response to the knocking down of RHOG, CDC42 or RAC1. …”
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Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders by Jaunetta Hill (18255631)

“…More importantly, the proteome of treated cells displayed ~75% of the downregulated products as SP1 targets. …”

Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants by Snigdhendubala Pradhan (9872262)

“…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …”

Successful endoscopic management of gastrojejunal anastomotic strictures after Roux-en-Y gastric bypas by Azar, Riad

“…Dilation to at least 15 mm is safe and decreases the need for further endoscopic dilation.…”
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A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion by Issa, Elio

“…The limited requests for retribution are likely due to a sense of impunity and adaptation to cumulative trauma. …”
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Evaluation of transportation network reliability during unexpected events with multiple uncertainties by El Khoury, John

“…These uncertainties are likely due to the effect of natural disasters on road networks. …”
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