Enhanced generation of beta cell precursors and functional insulin-secreting cells from human pluripotent stem cells by Bushra Memon (4792767)

“…The transcriptome profile of PDX1−/NKX6.1+-derived beta cells was closely like those of human pancreatic islets and purified hPSC-derived beta cells.…”

Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12 by Kripa S Keyan (10644815)

“…Instead, <i>TRIP12</i> recruits SMURF2 to SMAD4, which is most likely responsible for inhibitory monoubiquitination of SMAD4, since SMAD4 monoubiquitination and its interaction with SMURF2 were dramatically downregulated in <i>TRIP12</i>^<em>-</em>^/- cells. …”

Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis by Alaa Abd-Alrazaq (17430900)

“…There are practical considerations that, if incorporated into the system, are likely to improve its adoption rate: Patient Online should be useful, easy to use, secure, and easy to access. …”

The Study of Maternal Factors and Their Association with Risk of Preterm Birth by Alaa Al-Naama (17075063)

“…We hypothesize that certain maternal factors increase the risk of PTBs.</p> <h3>Design</h3> <p>A retrospective study recruiting women in labor at WWRC from June 2022 until February 2023.…”

Impact of the COVID-19 lockdown on lifestyle behaviors and their association with personality among adults in Qatar: A cross-sectional study by Tamara Al-Abdi (8710488)

“…Openness was positively associated with all PA (<i>p </i>= 0.027), including walking (<i>p </i> = 0.026), and negatively associated with sitting (<i>p </i> = 0.038) before lockdown, while participants with high scores for neuroticism were less likely to be sitting during lockdown (<i>p </i> = 0.042). …”

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... by Alize J, Ferrari

“…Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47·8% (43·3–51·7) and for diarrhoeal diseases decreased by 47·0% (39·9–52·9). …”
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Computed tomography-detected hemothorax after blunt chest trauma: Does everyone need an intervention? A retrospective analysis by Ismail Mahmood (14150352)

“…Patients with larger hemothorax volumes were significantly more likely to require tube thoracostomy (<i>p</i> = 0.001) and had significantly longer hospital stays (<i>p</i> = 0.021). …”

Investigating the incidence, nature, severity and potential causality of medication errors in hospital settings in Qatar by Binny Thomas (5801969)

“…Effort is required to increase the effectiveness and efficiency of the reporting system. …”

Hurdling the Challenges of the 2019 IAAF World Championships by Olivier Girard (409080)

“…In particular, athletes are likely to encounter challenging hot temperatures and potentially high humidity levels that may eventually impair performance during middle and long distance events and increase the risk of exertional heat. …”

A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater by Azar, Riad

“…We anticipate that the debate on the roles of surgery and endoscopy in the treatment of small cancerous tumors will likely increase as experience with endoscopic resection increases. …”
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RFX3 is essential for the generation of functional human pancreatic islets from stem cells by Bushra Memon (4792767)

“…Despite a significant reduction in the expression levels of pancreatic islet hormones, the pan-endocrine marker chromogranin A remained unchanged at both EP and islet stages, likely due to an increase in the abundance of enterochromaffin cells (ECs). …”

Road deaths and injuries in India: Action required on the five pillars of road safety by Gopalakrishna Gururaj (19807233)

“…While urban deaths account for nearly a fifth of total deaths and injuries, Indian highways account for more than 50% of deaths and injuries and are likely to increase with further growth in infrastructure (1). …”

Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study by Mona Abdi (10196665)

“…Moreover, homozygous variants were found in 7 families (25.9%), with a sixfold increase in homozygous burden in consanguineous versus non-consanguineous families (13.6% and 1.8%, respectively). …”

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 by Hedyeh Ebrahimi (7321358)

“…Global age-standardised incidence rates of tracheal, bronchus, and lung cancer decreased by 7·4% (−16·8 to 1·6) and age-standardised incidence rates of larynx cancer decreased by 3·0% (−10·5 to 5·0) in males over the past decade; however, during the same period, age-standardised incidence rates in females increased by 0·9% (−8·2 to 10·2) for tracheal, bronchus, and lung cancer and decreased by 0·5% (−8·4 to 8·1) for larynx cancer. …”

Holistic Transitional Approach of Humanitarian Shelters Through The Implementation of Adaptable Design Strategies. by ALSHALABI, WASEEM

“…The issue of forcibly displaced portions of a population has become an emerging global trend that is driven by significantly increased numbers of displaced people. This is caused by increases in natural disasters due to global warming, war, and other conflicts. …”
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Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases by Glazer, Evan

“…The high rate of false-negative results is likely due to metabolic inhibition caused by chemotherapeutic drugs. …”
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New media and new practices of exploitation by Uzunoglu, Sarphan

“…Today, in new media sphere, tracking technologies replaced rating systems and data about consumer is being sold. Increasing use of new media and increasing Internet penetration through rising sales numbers of mobile devices caused a necessity for a new debate. …”
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Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 by Marie, Ng

“…Assuming the continuation of historical trends, by 2050, we forecast that the total number of adults living with overweight and obesity will reach 3·80 billion (95% UI 3·39–4·04), over half of the likely global adult population at that time. While China, India, and the USA will continue to constitute a large proportion of the global population with overweight and obesity, the number in the sub-Saharan Africa super-region is forecasted to increase by 254·8% (234·4–269·5). …”
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2·5th and 97·5th percentile values across the draws. …”
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Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Brittney S Sheena (9715568)

“…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …”