Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells by Castellino, R.C.

“…However, sunitinib did not induce apoptosis in either cell line at any time point, indicating that the anti-migratory effects of sunitinib were not due to impeding cell survival. …”
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In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation by Sleiman, Sama F.

“…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). When OGD was imposed following a 2-hr hypoxic stabilization of ODD-luc, the levels of the reporter were reduced, consistent with prior models proposing that OGD enhances HIF prolylhydroxylase (PHD) activity. …”
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Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM) by Mohammad, Hadi Ahmad

“…All the scenarios present increasing minimum and maximum temperatures and decreasing precipitation, except for RCP8.5, which predicted a more adverse trend. …”
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Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses by Merilyn Lock (9440240)

“…Data were sub-grouped for men and women, baseline training level, mean age, intervention type, and intervention length. …”

Dietary Calcium Intake of 1200 mg/d May Have Negative Correlation on Percent Body Fat by Dimassi, Hani I.

“…The high-calcium group (intake ≥1200 mg/d) had a significantly higher mean caloric intake (P ≤ .01) and significantly lower percent body fat (P ≤ .05) than the low-calcium group (intake <1200 mg/d). …”
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Chronic reduction of store operated Ca²⁺ entry is viable therapeutically but is associated with cardiovascular complications by Fang Yu (156838)

“…They further establish the SOCE hypomorph line as a genetic model to define the therapeutic window of SOCE inhibition and dissect toxicities associated with chronic SOCE inhibition in a tissue-specific fashion.…”

Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study by Obaidullah Zafar (17910572)

“…Hemoglobin levels significantly increased from 6.4 to 11.1 g/dl (<i>p</i> < 0.001) after IV iron treatment, as did ferritin levels, while total iron-binding capacity decreased. No complications, mortality, or morbidity were reported. …”

The effect of StarD13 on colorectal cancer proliferation and invasion. (c2013) by Nasrallah, Anita I.

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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects by Majdi Mansouri (16869885)

“…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …”

Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”

The impact of green supply chain management practices on environmental performance during COVID-19 period: the case of discretionary companies in the G-20 countries by El Khoury, Rim

“…It highlights the impact of green initiatives to cope with major disruptions and decrease pollution and environmental disaster.…”
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STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration by Ayat S. Hammad (9592374)

“…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca²⁺ entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …”

Driving simulation sickness and the sense of presence: Correlation and contributing factors by Mustafa Almallah (17280568)

“…Importantly, designing buildings that replicate a real-world environment could increase SP and decrease SS. Moreover, designing high quality and resolution scenarios could also increase SP, thus decreasing the severity of SS symptoms. …”

Distinctive role of starD 13 in serous ovarian carcinoma cell proliferation, metastasis, and invadopodia assembly. (c2019) by Abdullatef, Sandra

“…Serous epithelial carcinomas have a poor treatment rates for it is most likely to be advanced when diagnosed due to its poor indications and symptoms. …”
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Enhancing Security and Performance in Live VM Migration: A Machine Learning‐Driven Framework With Selective Encryption for Enhanced Security and Performance in Cloud Computing Envi... by Raseena M. Haris (17773470)

“…However, concerns persist regarding safeguarding sensitive data during migration, particularly in critical sectors like healthcare, banking and military operations. …”

Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles by Nuri C. Onat (14779093)

“…<p dir="ltr">Autonomous vehicles offer greater passenger convenience and improved fuel efficiency. However, they are likely to increase road transport activity and life cycle greenhouse emissions, due to several rebound effects. …”

Nonlinear Multimode Vibration Attenuation Using Passive Circuits by Kadri, Khaled

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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shehaby, Wassim N.

“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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