Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

"…Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. Therefore, more selective and efficient therapeutic methods for targeting GBM are needed. …"
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Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas حسب Tejedor, Alejandro

"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta... حسب Mohammed M. Al-Humaiqani (18325554)

"…Additionally, the BESs were ranked concerning accepting the change and uncertainty inherited from the past or generated over time. This study emphasized the perception that the decision-making domain is crucial for delivering a reflective built environment. …"

The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013) حسب Khoury, Nathalie El

"…In this study, we aim to determine a possible mechanism of action of kefir and to study its effect on the motility of colorectal and breast cancer cell lines. Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …"
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Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models حسب Ben Romdhane, Haifa

"…Furthermore, results demonstrated that the probability of severe damage increases with decreasing water oxygenation and with increasing temperature, light, salinity, acidity and nutrient levels. …"
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Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud... حسب Robert C Reiner (5147636)

"…Findings The greatest declines in diarrhoeal mortality were seen in south and southeast Asia and South America, where 54·0% (95% uncertainty interval [UI] 38·1–65·8), 17·4% (7·7–28·4), and 59·5% (34·2–86·9) of units, respectively, recorded decreases in deaths from diarrhoea greater than 10%. …"

Microwave-Assisted Solvothermal Synthesis of Mo-Doped TiO₂ with Exceptional Textural Properties and Superior Adsorption Kinetics حسب Yahia H. Ahmad (14340210)

"…The uniform effective heating delivered by microwave heating reduced the reaction time to less than 30 min, representing several orders of magnitude lower than conventional heating methods. …"

Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 حسب Austin, Carter

"…Additionally, we introduced two new metrics to our reporting: prevalence of unsuppressed viraemia (PUV), which represents the proportion of the population without a suppressed level of HIV (viral load <1000 copies per mL), and period lifetime probability of HIV acquisition, which quantifies the hypothetical probability of acquiring HIV for a synthetic cohort, a simulated population that is aged from birth to death through the set of age-specific incidence rates of a given time period. FindingsGlobal new HIV infections decreased by 21·9% (95% UI 13·1–28·8) between 2010 and 2021, from 2·11 million (2·02–2·25) in 2010 to 1·65 million (1·48–1·82) in 2021. …"
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Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …"

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death حسب Tohme, Sara

"…In this study, we showed for the first time that arginine deprivation using a recombinant human arginase induces ferroptosis, an autophagy-mediated type of cell death in AML cells. …"
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Total Quality Implementation on Marine Transportation Association Under Natural Disruption of COVID-19 Pandemic حسب ASAD, NUHA JAMAL

"…Social distancing, i.e., decreasing collaborations between people to dial back the spread of the infection, has turned into the new standard. …"
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COPE for adolescent Syrian refugees in Lebanon: a brief cognitive–behavioral skill-building intervention to improve quality of life and promote positive mental health حسب Doumit, Rita

"…COPE is an effective cognitive–behavioral intervention that can be delivered in an Arabic/Middle-Eastern setting for teen refugees to improve mental health and QOL.…"
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Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications حسب Tooba Yasin (19131382)

"…The biocompatibility of the composite hydrogels has been evaluated using fibroblast cell lines (<i>3T3</i>) after different time intervals (24–72 h), and it was found that increasing ZiF-8 caused the mature and spread cell morphology with increasing cell viability and proliferation under controlled in vitro conditions. …"

Effectiveness and specificity of a classroom-based group intervention in children and adolescents exposed to war in Lebanon حسب Dimassi, Hani

"…These findings have significant policy and public health implications, given current practices of delivering universal interventions immediately post-war.…"
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Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review حسب Ibrahim, Mihad

"…Nanoparticles can be used as vehicles for the localized delivery and release of DOX, decreasing the effects on neighboring healthy cells and providing more control over the drug’s release and distribution. …"
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Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review حسب Ibrahim, Mihad

"…Nanoparticles can be used as vehicles for the localized delivery and release of DOX, decreasing the effects on neighboring healthy cells and providing more control over the drug’s release and distribution. …"
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Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells حسب Tawil, Mirna

"…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …"
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Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis حسب HASHEM ABU SERHAN (19737499)

"…In vitrectomized eyes, notable decreases were observed: at 30 min, the Ratio of Means (ROM) was 0.81 (95% CI: 0.53; 1.24), indicating a 19% reduction; at 60 min, the ROM of 0.833 (95% CI: 0.77; 0.89) showed a 16.7% reduction; at 90 min, the ROM of 0.757 (95% CI: 0.755; 0.758) corresponded to a 24.3% reduction; at 2 h, the ROM of 0.726 (95% CI: 0.642; 0.820) reflected a 27.4% reduction; at 3 h, the ROM of 0.692 (95% CI: 0.600; 0.797) resulted in a 30.8% reduction; and at 4 h, the ROM of 0.700 (95% CI: 0.363; 1.350) indicated a 30% reduction. …"

Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells حسب Haidar, Fatemah

"…In this project, we first inspected ASS-1 expression in human breast cancer patients and found that it decreases progressively with tumorigenesis and metastasis. …"
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