Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”

Efficacy And Safety of Cannabidiol on Juvenile Diabetes Outcomes in Male Rats by Awkar, Nai

“…Thus, CBD has the potential to decrease HbA1C in diabetic patients (Diabetes Mellitus type 1) and improve their lives. …”
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Electric vehicles charging management using deep reinforcement learning considering vehicle-to-grid operation and battery degradation by Mostafa M. Shibl (17821382)

“…<p>EVs are becoming more popular and widely used worldwide due to their environmentally friendliness as part of the world efforts to decrease the effects of climate change. Moreover, more users are buying EVs due to governmental incentives, development of charging technologies and cheaper maintenance costs. …”

Teachers’ Job Satisfaction in Instructional Delivery Modalities, and the Role of School Leaders: a Study among Selected Private Schools in Abu Dhabi. by YAHYA, AHMAD

“…This result is derived from the change in the outcomes of the satisfaction factors: job security, workload, in-class effort, work-life balance, remuneration, leadership support, students’ behaviour, and relationship with co-workers. …”
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Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes by Abushanab, Dina

“…AimsInsufficient risk factor control can lead to a loss of millions of productivity-adjusted life years (PALYs). We aimed to assess the productivity burden of cardiovascular disease (CVD) in type 2 diabetes (T2D) and examine the potential advantages of enhancing the control of modifiable CVD risk factors in Qatar. …”
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STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration by Ayat S. Hammad (9592374)

“…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca²⁺ entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …”

The impact of green supply chain management practices on environmental performance during COVID-19 period: the case of discretionary companies in the G-20 countries by El Khoury, Rim

“…It highlights the impact of green initiatives to cope with major disruptions and decrease pollution and environmental disaster.…”
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Driving simulation sickness and the sense of presence: Correlation and contributing factors by Mustafa Almallah (17280568)

“…Importantly, designing buildings that replicate a real-world environment could increase SP and decrease SS. Moreover, designing high quality and resolution scenarios could also increase SP, thus decreasing the severity of SS symptoms. …”

Distinctive role of starD 13 in serous ovarian carcinoma cell proliferation, metastasis, and invadopodia assembly. (c2019) by Abdullatef, Sandra

“…Serous epithelial carcinomas have a poor treatment rates for it is most likely to be advanced when diagnosed due to its poor indications and symptoms. …”
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Nonlinear Multimode Vibration Attenuation Using Passive Circuits by Kadri, Khaled

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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shehaby, Wassim N.

“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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Expanding the donor pool by Ramos, Emilio

“…These measures may be beneficial in terms of increasing the number of donors and decreasing the waiting time. However, deviation from the standard method of cadaver donor selection is not without possible negative impact on graft survival. …”
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Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma by Shebaby, W.

“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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The DJ-1 superfamily members YhbO and YajL from Escherichia coli repair proteins from glycation by methylglyoxal and glyoxal by Abdallah, Jad

“…Both proteins are involved in protection against environmental stresses. Here, we show that, like DJ-1 and Hsp31, they repair glyoxal- and methylglyoxal-glycated proteins. …”
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Effect of StarD13 on colorectal cancer proliferation, motility and invasion by Nasrallah, Anita

“…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …”
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Road safety and traffic medicine in Iran: Achievements and challenges by A. Motevalian (19807242)

“…<p dir="ltr">Road traffic injuries found to be the second rank of Years of Life Lost (YLL) and third rank of Disability Adjusted Life Years (DALY) in Iran based on Global Burden of Disease 2010. …”

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro by Rizk, Sandra

“…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression by Rayanah Barnawi (8737584)

“…Herein, fascin ShRNA was used to generate stable fascin knockdown (FSCN1^KD) in the MDA-MB-231 TNBC cell line and then were subjected to comprehensive mRNA and miRNA transcriptome analysis. …”

Reinforcement R-learning model for time scheduling of on-demand fog placement by Farhat, Peter

“…Nevertheless, taking a real-life scenario, the cloud might limit the number of fogs to place for minimizing the complexity of monitoring a large number of fogs and cost for volunteers that do not offer their resources for free. …”
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