Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 حسب Letourneau, Ian D

"…Although mortality rates due to appendicitis decreased in all regions, there were large regional variations in the temporal trend in incidence. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The burden of prostate cancer in North Africa and Middle East, 1990–2019: Findings from the global burden of disease study حسب Mohsen Abbasi-Kangevari (9714440)

"…This study presents estimates of PCa prevalence, incidence, death, years-of-life-lost (YLLs), years-lived-with-disability (YLDs), disability-adjusted-life-years (DALYs), and the burden attributable to smoking during 1990-2019 in North Africa and Middle East using data of Global Burden of Diseases (GBD) Study 2019.…"

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Hedyeh Ebrahimi (7321358)

"…</p><p><br></p><h3>Methods</h3><p dir="ltr">Based on the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 methodology, we evaluated the incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs) of respiratory tract cancers (ie, tracheal, bronchus, and lung cancer and larynx cancer). …"

Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application حسب Lama Soubra (11666333)

"…Pharmacists can play a substantial role in decreasing the burden of the disease.</p><h3>Purpose</h3><p dir="ltr">The primary aim of this study was to develop and validate a scale assessing the pharmacist role in hypertension management in the community pharmacy setting. …"

Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Joseph L Ward (9715619)

"…Since 1950, deaths in this age group decreased by 30·0% in females and 15·3% in males, and sex-based differences in mortality rate have widened in most regions of the world. …"

Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells حسب Tawil, Mirna

"…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

"…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells حسب Haidar, Fatemah

"…In this project, we first inspected ASS-1 expression in human breast cancer patients and found that it decreases progressively with tumorigenesis and metastasis. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment حسب Farhat, Peter

"…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Intravitreal adalimumab in active noninfectious uveitis حسب Hamam, Rola N.

"…Seven out of 12 eyes had improvement of ≥2 ETDRS lines. Three out of three eyes had resolution of anterior chamber cells. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review حسب Ibrahim, Mihad

"…However, its effective utilization is hindered by the adverse side effects associated with its administration, the detriment to the patients’ quality of life, and general toxicity to healthy fast-dividing cells. …"
احصل على النص الكامل

Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review حسب Ibrahim, Mihad

"…However, its effective utilization is hindered by the adverse side effects associated with its administration, the detriment to the patients’ quality of life, and general toxicity to healthy fast-dividing cells. …"
احصل على النص الكامل

Genotypic and phenotypic characterization of Candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin حسب Toutounji, Maggie

"…Caspofungin sensitive strains showed decreased resistance to Congo red yet increased virulence and biofilm formation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging حسب Farooq, Afifa

"…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …"
احصل على النص الكامل

Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging حسب Farooq, Afifa

"…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …"
احصل على النص الكامل

Genotypic and phenotypic characterization of candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin. (c2018) حسب Toutounji, Maggie Nazih

"…Caspofungin sensitive strains showed decreased resistance to Congo red yet increased virulence and biofilm formation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Enhanced oil recovery using hyperbranched polyglycerol polymer-coated silica nanoparticles حسب Wamda Faisal Elmobarak (17058024)

"…The %η_dem improved as the C_sur and pH decreased, with maximum values of 98.8% and 98.5% achieved at C_sur = 0.05 g/L and a pH = 4, respectively. …"

Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System حسب Bair, Scott

"…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Road safety and traffic medicine in Iran: Achievements and challenges حسب A. Motevalian (19807242)

"…<p dir="ltr">Road traffic injuries found to be the second rank of Years of Life Lost (YLL) and third rank of Disability Adjusted Life Years (DALY) in Iran based on Global Burden of Disease 2010. …"