Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells حسب Castellino, R.C.

"…However, sunitinib did not induce apoptosis in either cell line at any time point, indicating that the anti-migratory effects of sunitinib were not due to impeding cell survival. …"
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In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation حسب Sleiman, Sama F.

"…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). When OGD was imposed following a 2-hr hypoxic stabilization of ODD-luc, the levels of the reporter were reduced, consistent with prior models proposing that OGD enhances HIF prolylhydroxylase (PHD) activity. …"
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Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021 حسب Nicholas, Steel

"…In 2019–21, there was an overall decrease in mean annual life expectancy across all countries (overall mean –0·18 years [95% UI –0·22 to –0·13]), with all countries having an absolute fall in life expectancy except for Ireland, Iceland, Sweden, Norway, and Denmark, which showed marginal improvement in life expectancy, and Belgium, which showed no change in life expectancy. …"
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Experimental and Analytical Investigations of the Use of Groove-Epoxy Anchorage System for Shear Strengthening of RC Beams Using CFRP Laminates حسب Mohamed, Khalid Mustafa Elradi

"…The developed models predicted the experimental shear-strength of the tested RC beams with a good level of accuracy, with an average mean absolute percent error (MAPE) = 3.31% and 6.68%, normalized mean square error (NMSE) = 0.072, 0.523, and coefficient of determination R2 = 0.964, 0.691, for plates and sheets, respectively.…"
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IS security menace حسب Balozian, Puzant

"…It is widely believed in IS security literature that enforcing IS security policy compliance on employees through various means is the solution for security effectiveness. …"
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Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study حسب Abduljaleel Abdullatif Zainel (18055382)

"…Higher levels of anger, depression, and general anxiety were prevalent among 1.3% (n=84), 3.9% (n=260), and 1.6% (n=104) of participants, respectively. The mean score for the emotional constructs anger and depression decreased with increased compliance with regulations (<i>P</i>=.04 and <i>P</i>=.11, respectively). …"

STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration حسب Ayat S. Hammad (9592374)

"…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …"

The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000) حسب Jabre, Mazen Gerges

"…The mean levodopa dose was reduced by 90% (p < 0.01), while the mean dopamine agonist dose was increased by 15% from preoperative level. …"
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An experimental measurement of corona discharge using laser Dopplervelocimetry حسب Belhadj, C.A.

"…The corona wind velocity was measured by means of a laser Doppler velocimetry system implemented and calibrated in the laboratory. …"
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The downsides of information systems security policy compliance efforts حسب Balozian, Puzant

"…It is widely believed in IS security literature that enforcing IS security policy compliance on employees through various means is the solution for security effectiveness. …"
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Outcome of home parenteral nutrition in 251 children over a 14-y period حسب Abi Nader, Elie

"…Results: A total of 251 patients were included: 217 (86%) had a PDD. The mean ± SD age at HPN onset was 0.7 ± 0.3 y, with a mean duration of 1.9 ± 0.4 y. …"
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Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis حسب Osama Hussein (21301202)

"…In ACG patients, the pooled effect showed a percentage of IOP reduction (IOPR%) of 35.22% with a mean IOP reduction of −9.51 mmHg, <i>p</i>< 0.001 at 12 months, and an IOPR% of 27.47% with a mean reduction of −6.37 mmHg, <i>p</i> < 0.001 at 24 months. …"

Effectiveness of external myofascial mobilisation in the management of male chronic pelvic pain of muscle spastic type: A retrospective study حسب M. S Ajimsha (21250760)

"…The mean (SD) NIH-CPSI score at initial evaluation was 29.41 (8.3) and decreased to 9.14 (3.45) after the fifth visit. …"

Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression حسب Rayanah Barnawi (8737584)

"…Herein, fascin ShRNA was used to generate stable fascin knockdown (FSCN1^KD) in the MDA-MB-231 TNBC cell line and then were subjected to comprehensive mRNA and miRNA transcriptome analysis. …"

On the sampling and integration rates of process noise حسب Saab, Samer S.

"…It is shown that the covariance of a sampled zero-mean exponentially-correlated process is independent of the sampling rate. …"
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Testing and Evaluation of a Smart Irrigation System Towards Smart Landscaping in UAE حسب Al Sulaimani, Fatma

"…The outcomes of the use of SMS have shown better results in water conservation, 21%, and 26% decrease in water consumption for the months of September and October, respectively.…"
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Causes of Delay in Construction Projects in Oil and Gas Construction Industry حسب FANOUSSE, MARWA IMAD

"…With regard to design, the contractor’s need to decrease construction costs through a cheaper design was found to be a factor in design changes. …"
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Writing and publishing language studies in the Arab region [Khitabaat Journal] حسب Emad Abdul-latif (21841985)

"…Klein starts from an implicit assumption that writing and reading are individual activities and suggests that (individual) writers must decrease their production to enable their (individual) readers to read it. …"

Grid electricity demand reduction through applying passive and active strategies for a house in Baghdad, Iraq حسب Al-Badri, Nadia Rashid

"…By adopting 1Pearl, it provided 4.33% energy reduction while 2 Pearls can achieve about 4.37% decrease in energy. This means that roof insulation should take priority when considering the passive solutions for conserving energy. …"
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Differential water quality in confined and free-flowing water bodies, Lebanon حسب Korfali, Samira Ibrahim

"…This emphasises the importance of assessing surface water quality as a projected means to increase water availability. This study involves two different water bodies, the freely flowing Nahr-Ibrahin River and the Qaraaoun Reservoir, an impoundment of the Litani River. …"
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