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261
Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …”
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masterThesis -
262
Investigation of Forming a Framework to shortlist contractors in the tendering phase
Published 2022“…For the consultant, it will decrease the load of going through numerous tender packages and ensuring that the best companies will tender for the project. …”
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263
Catalytic Transformation Of C-7-C9 Methyl Benzenes Over USY-Based FCC Zeolite Catalyst
Published 2020“…The sequence of reactivity of the three alkyl benzenes was found to decrease as the number of methyl group per benzene ring decreases, as follows: 1,2,4-trimethylbenzene > m-xylene > toluene. …”
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264
Modulation of Chronic Stress Outcomes by Dietary Sweeteners: A Comparative Study of Sucrose and Aspartame in Mice
Published 2025“…Body fat and serum corticosterone were measured at multiple time points. Behavioral tests for anxiety, sociability, and cognition were conducted in the final week. …”
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masterThesis -
265
Project Portfolio Management for Successful Major IT Projects in Global Telecommunication Organization
Published 2011“…The research indicated that these factors like scope, time and cost of a project are not enough to control IT projects and obtain the expected result. …”
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266
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…To explore the relationship between the antibody responses and time, Spearman's correlation coefficient was computed. …”
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267
Differential water quality in confined and free-flowing water bodies, Lebanon
Published 2003“…This emphasises the importance of assessing surface water quality as a projected means to increase water availability. This study involves two different water bodies, the freely flowing Nahr-Ibrahin River and the Qaraaoun Reservoir, an impoundment of the Litani River. …”
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268
Testing and Evaluation of a Smart Irrigation System towards Smart landscaping in UAE
Published 2017“…The outcomes of the use of SMS have shown a better results in water conservation and a decrease in water flow in the month of September by 21% and 26% in October. …”
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269
A framework for implementing Green Supply Chain Management: The Case of Petco Gulf
Published 2021“…From this research, it was found that as Petco gulf is present in the U.A.E. it can take advantage of this and by applying the GSCM strategies against each of its components this will help the company by, increased overall gross profit with the decrease in cost since going green in its supply chain means reducing the overheads. …”
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270
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
Published 2014“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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271
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
Published 2013“…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). When OGD was imposed following a 2-hr hypoxic stabilization of ODD-luc, the levels of the reporter were reduced, consistent with prior models proposing that OGD enhances HIF prolylhydroxylase (PHD) activity. …”
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272
D 2IA: User-defined interval analytics on distributed streams
Published 2019“…In most of the cases, data items and events are considered instantaneous, i.e., they are single time points in a discrete temporal domain. Nevertheless, a point-based time semantics does not satisfy the requirements of a number of use-cases. …”
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273
1,2,4-Trimethylbenzene Transformation Reaction Compared With Its Transalkylation Reaction With Toluene Over USY Zeolite
Published 2020“…Kinetic parameters for the 1,2,4-TMB disappearance during the transalkylation reaction and in its conversion into isomerization and disproportionation products were calculated using the catalyst activity decay function based on time on stream (TOS). The apparent activation energies were found to decrease as follows: E-transalkylation > E-isomerization > E-disproportionation.…”
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274
A new perspective on cardiovascular drift during prolonged exercise
Published 2021“…<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. …”
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275
Dietary Calcium Intake of 1200 mg/d May Have Negative Correlation on Percent Body Fat
Published 2006“…The high-calcium group (intake ≥1200 mg/d) had a significantly higher mean caloric intake (P ≤ .01) and significantly lower percent body fat (P ≤ .05) than the low-calcium group (intake <1200 mg/d). …”
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276
OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo...
Published 2023“…The couple's relationship quality also plays a significant role, with secure romantic attachment positively influencing prenatal attachment and promoting resilience in times of stress, while avoidant or anxious romantic attachment can lead to lower prenatal bonding and increased pregnancy-related worries.…”
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277
Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon
Published 2011“…Increasing the dose to 500 mg/kg body weight caused a significant decrease in stool water content. No adverse effect on liver enzymes was observed. …”
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278
Modeling circadian clock–cell cycle interaction effects on cell population growth rates
Published 2014“…Particularly, we show that Cry 1, Cry 2 mutations decrease the growth rate of cells, Per 2 mutation enhances it and Bmal 1 knockout increases it for autonomous periods of the cell cycle less than 21 h and decreases it elsewhere. …”
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279
Artificial neural network algorithms. (c1999)
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masterThesis -
280
Successful Use of Intravenous B-blocker Therapy in Cardiogenic Shock Supported With Venoarterial Extracorporeal Membrane Oxygenation: A Case Series
Published 2022“…<p dir="ltr">Tachycardia in cardiogenic shock (CS) might reduce the cardiac output (CO) by decreasing the ventricular filling time. Nevertheless, heart rate (HR) control with agents that possess negative inotropy might decrease the CO. …”