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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
Published 2020“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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masterThesis -
243
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”
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244
Efficacy And Safety of Cannabidiol on Juvenile Diabetes Outcomes in Male Rats
Published 2023“…CBD presents desirable effects on hyperglycemia by protecting against oxidative stress and inflammation, having neuroprotective properties, and acting on receptors linked to glycemia. Thus, CBD has the potential to decrease HbA1C in diabetic patients (Diabetes Mellitus type 1) and improve their lives. …”
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masterThesis -
245
Polyaniline/Polystyrene Blends: In-Depth Analysis of the Effect of Sulfonic Acid Dopant Concentration on AC Conductivity Using Broadband Dielectric Spectroscopy
Published 2018“…The conductivity is discussed in terms of changes in the dielectric permittivity storage <em>(ɛʼ)</em>, loss <em>(ɛʼʼ)</em>, and modulus <em>(Mʼʼ)</em> of the blends over a wide range of temperatures. This is linked to the glass transition temperature of the PANI. …”
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246
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
Published 2023“…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca<sup>2+</sup> entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …”
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247
Driving simulation sickness and the sense of presence: Correlation and contributing factors
Published 2021“…Importantly, designing buildings that replicate a real-world environment could increase SP and decrease SS. Moreover, designing high quality and resolution scenarios could also increase SP, thus decreasing the severity of SS symptoms. …”
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248
Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes
Published 2018“…There was a significant decrease in PTEN activity as evident by a rise in the phosphorylated form of this protein. …”
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249
Structural Hole Theory, Audit Committee Member Gender, and Financial Restatements
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doctoralThesis -
250
Expanding the donor pool
Published 2002“…These measures may be beneficial in terms of increasing the number of donors and decreasing the waiting time. However, deviation from the standard method of cadaver donor selection is not without possible negative impact on graft survival. …”
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251
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
Published 2015“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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252
Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma
Published 2015“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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253
Effect of StarD13 on colorectal cancer proliferation, motility and invasion
Published 2014“…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …”
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254
Essays on international environmental policy
Published 2009“…However, since countries are linked via trade, tying-in environmental and trade agreements generates negative spillovers over defectors. …”
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masterThesis -
255
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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256
Effect of acute and chronic moderate alcohol consumption on fasted and postprandial lipemia in the rat
Published 2003“…In the chronic study, animals received, for a period of 10 weeks, 3% alcohol in drinking water in the form of ethanol, beer or whisky. …”
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257
Removal of phenols and dyes from aqueous solutions using graphene and graphene composite adsorption: A review
Published 2021“…Amongst the different technologies used to decrease pollutant levels in water, adsorption technology is highly effective even at low pollutant concentrations. …”
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258
Life cycle assessment of compressed air, vanadium redox flow battery, and molten salt systems for renewable energy storage
Published 2021“…However, greenhouse gas emissions associated with the energy storage methods have received insufficient attention, especially for arid climate implementation. …”
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259
An Exploration of Smoking Patterns Among People with Serious Mental Illness Attending an Outpatient Clinic in Qatar
Published 2022“…Many countries worldwide have observed a decrease in the prevalence of tobacco smoking; however, the smoking rates among people with SMI have declined much less than in those without mental illness. …”
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260
Energy-Efficient Cell Association and Load Balancing for Low Battery Users in Heterogeneous Cellular Networks
Published 2025“…This paper proposes improved cell association schemes based on the battery levels of UE and Deep Q-learning (DQL) to achieve load balancing and to decrease the power consumption of Low Battery Users (LBUs). …”