Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response by Mingzhan Xue (3607649)

“…It thereby poses a major challenge to proteostasis and activates UPR sensors. Pharmacological decrease of MG with Glo1 inducer, trans-resveratrol and hesperetin in combination, offers a novel treatment strategy to counter UPR-related cell dysfunction, particularly in hyperglycemia associated with diabetes.…”

PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development by Sahar I. Da’as (9631717)

“…The zebrafish functional modeling of PGAP3 loss resulted in HPMRS4-like features, including structural brain abnormalities, dysmorphic cranial and facial features, hypotonia, and seizure-like behavior. …”

Association between thermal responses, medical events, performance, heat acclimation and health status in male and female elite athletes during the 2019 Doha World Athletics Champi... by Sebastien Racinais (318896)

“…T_corewas not related to DNF (25% of starters) or medical events (p≥0.150), whereas T_skin, T_skin rate of decrease and T_core-to-T_skin gradient were (p≤0.029). …”

Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes by Abu Saleh Md Moin (6189512)

“…However, it is equally likely that this may be a reflection of new cell formation as a frank regenerative response to ongoing tissue injury. …”

Simulation of the size-composition distribution of atmospheric nanoparticles over Europe by David Patoulias (4722960)

“…The ground level concentrations of particles with a diameter larger than 100 nm (N100) were reproduced with a daily normalized mean error of 40 % and a daily normalized mean bias of −20 %. …”

Which factor explains the life‐history of <i>Xanthium strumarium</i> L., an aggressive alien invasive plant species, along its altitudinal gradient? by Rafi Ullah (8146836)

“…Among climatic variables, mean yearly temperature, mean annual yearly humidity, and mean day length in hours, while in soil variables, organic matter and nitrogen percentage significantly affect the phenological and morphological stages. …”

Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar by Shikha, Patel

“…The LST data derived from remote sensing sources demonstrates an upward trend for summer and a contrasting trend for winter. Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …”
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Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet by Neelam Iftikhar (14778400)

“…Higher doses of <i>Hibiscus rosa-sinensis</i> significantly decreased the levels of AST, ALT, AP, and SC in comparison with the HFSDC group. …”

Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study by Zeana, Samir AlKudsi

“…Participants had shown moderate resilience (mean score: 27.64 (SD = 8.31)) and their mean score fear of COVID19 was 15.67 (SD = 6.54). …”
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Impact of staying at home measures during COVID-19 pandemic on the lifestyle of Qatar’s population: Perceived changes in diet, physical activity, and body weight by Muna Abed Alah (14779534)

“…Participants reported increased sitting/reclining time (1.94 h/day mean increase), screen times (2.05 h/day mean increase) with p < 0.001, and decreased exercise time (0.11 h/day mean reduction) with p < 0.001. …”

Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar by Shikha Patel (14151027)

“…The LST data derived from remote sensing sources demonstrates an upward trend for summer and a contrasting trend for winter. Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …”

3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction by Masoud Forsat (14158980)

“…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. At first, simulation implemented on the comparison of the ground movements in the single and twin tunnels. …”

Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression by Rayanah Barnawi (8737584)

“…Expression of FSCN1^high (identified in BRCA dataset from TCGA) in conjunction with elevated expression of the top 10 upregulated or decreased expression of the top 10 downregulated genes (identified in our FSCN1^CON vs. …”

Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine by Salman M. Toor (8854751)

“…<p dir="ltr">The global burden of influenza-associated respiratory mortality is higher than previous estimates, with over 0.6 million deaths per year and additional mortality rates attributed to non-respiratory but influenza-related illnesses [1]. Numerous vaccines have been developed to protect against influenza infections. …”

From COVID-19 to clot: the involvement of the complement system by Mohamed A. Hendaus (9401919)

“…Agents that inhibit the terminal events of the complement cascade might be crucial for ensuring an efficient treatment, decrease clots and permit early discharge in relation to COVID-19.…”

Social Network Analysis for Precise Friend Suggestion for Twitter by Associating Multiple Networks Using ML by Dharmendra Kumar Singh Singh (19517710)

“…This approach is by and large used to decrease the dimensionality of the information alongside its feature space. …”

Wasted Da’am: Evaluating the Impact of Food Waste Management Practices on the Environment in Hotels in Qatar by Mohammed Abubakar Metcho (22674068)

“…Interestingly, the result showed that for every decrease in the number of guests, methane decreased by 0.009 kilograms, and the absence of technological efficiency increased methane by 3.30kg. …”

Redox Homeostasis and Inflammation Responses to Training in Adolescent Athletes: a Systematic Review and Meta-analysis by Evdokia Varamenti (8154642)

“…Following more extended training periods, GSH showed moderate increases (ES 1.131; 95% CI 0.350 to 1.913;<i>Z</i>= 2.839,<i>p</i>= 0.005) while TBARS displayed a small decrease (ES 0.568; 95% CI − 0.062 to 1.197;<i>Z</i>= 1.768,<i>p</i>= 0.077). …”

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”

STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration by Ayat S. Hammad (9592374)

“…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca²⁺ entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …”