The Antioxidant and Pro-apoptotic effects of Sternbergia clusiana Bulb Ethanolic Extract on Breast Cancer Cells in vitro by El Samarji, Mona

“…Among the various Amaryllidaceae species, Sternbergia clusiana has been recently given a great amount of attention in the medicinal field due to its richness in small chemical molecules, namely Amaryllidaceae alkaloids; these have been reported to possess an antioxidant and anti-inflammatory role, in addition to a prominent anti-cancer effect on different types of cancer cell lines. The current study investigates the selective anti-proliferative effect of Sternbergia clusiana bulb ethanolic extract (SbBEE) on breast cancer cells cultured in vitro (MDA-MB-231 and MCF-7) and reveals the underlying mechanism responsible for the induction of cell death. …”
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Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression by Rayanah Barnawi (8737584)

“…Expression of FSCN1^high (identified in BRCA dataset from TCGA) in conjunction with elevated expression of the top 10 upregulated or decreased expression of the top 10 downregulated genes (identified in our FSCN1^CON vs. …”

Slater to Mott Crossover in the Metal to Insulator Transition of Nd2⁢Ir2⁢O7 by Nakayama, M.

“…The quasiparticle peaks are strongly suppressed, however, with further decrease of temperature, and eventually vanish at the lowest temperature, leaving a nondispersive flat band lacking long-lived electrons. …”
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Metformin inhibits 2D and 3D motility in astrocytoma cancer cells. (c2014) by Hassan, Marwa Fouad Al

“…When this drug is applied, it led to a relative decrease in the proliferation of astrocytoma cancer cells. …”
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The impact of maternal care on child development by Sayour, Nagham

“…Results show that treated children enjoy an increase of 3.6 h per week in the time they spend with their mothers, mainly due to a decrease in the time spent in non-institutional care. …”
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The Role of KM in Enhancing AI Algorithms and Systems by AlGhanem, Hani

“…Finally, the study shows a decrease in the number of researches done for this topic in the selected databases, which can be enhanced by other researchers by examining other databases to increase results accuracy.…”
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The effects of blockchain implementation on Cyber risks mitigating strategies in the financial sector in the United Arab Emirates by SAADEH, YASSER MOHAMMED

“…This feature and other main success factors of blockchain encourage researchers to concentrate on the chances to benefit from blockchain in the efforts to decrease the effects of cyber threats on the business and improve the cyber defense. …”
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The construction of a categorisation system for Total Care Products by Ahmed, Murshed Mohamed

“…This imposes challenges that require a change in business models in which the price is related to the functionality, not to what the asset is worth. …”
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Achieving top performance while building collegiality in sales by Itani, Omar S.

“…Ethical climate is negatively related to workplace isolation and positively to teamwork. …”
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A Comparative study of Technical Efficiency in GCC Islamic Financial Institutions during the Global financial Crisis using Malmquist-Type Data Envelopment analysis by Al Hammadi, Khalid Faisal

“…The result also suggest that efficiency and IFI size is positively but weakly related. The study suggested some policy and managerial implications. …”
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Intracellular Ionic Strength Sensing Using NanoLuc by Tausif Altamash (3846304)

“…Biochemical experiments using a recombinantly purified protein showed that NanoLuc bioluminescence is dependent on the ionic strength of the reaction buffer for a wide range of ionic strength conditions. Importantly, the decrease in the NanoLuc activity observed at higher ionic strengths could be reversed by decreasing the ionic strength of the reaction, thus making it suitable for sensing intracellular ionic strength alterations. …”

Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells by Shebaby, Wassim N.

“…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …”
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Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas... by Parkes J Kendrick (9714851)

“…Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. …”

Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. by Sara, Sokary

“…Studies have shown that semaglutide reduced fat mass, particularly visceral fat, while preserving lean muscle mass, as the proportion relative to total body mass decreased by 3.5% and 2.0% for total and visceral fat mass, respectively, while it increased by 3.0% for lean body mass. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …”
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Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon by Mokhbat, Jacques M.

“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells by Castellino, R.C.

“…However, sunitinib did not induce apoptosis in either cell line at any time point, indicating that the anti-migratory effects of sunitinib were not due to impeding cell survival. …”
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In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation by Sleiman, Sama F.

“…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). When OGD was imposed following a 2-hr hypoxic stabilization of ODD-luc, the levels of the reporter were reduced, consistent with prior models proposing that OGD enhances HIF prolylhydroxylase (PHD) activity. …”
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Buckling Analysis of Functionally Graded Materials (FGM) Thin Plates with Various Circular Cutout Arrangements by Alashkar, Adnan

“…For instance, an increase in the plate thickness and a decrease in the cutout diameter increase the critical buckling load. …”
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Exercise-induced Citrate Enhances Associative Memory Formation by Modulating Histone Acetylation in a Sex-dependent manner by El Masri, Diala

“…Identifying these exercise-related factors could provide a detailed insight on the processes by which exercise exerts its positive effects on cognition. …”
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