Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”

STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration by Ayat S. Hammad (9592374)

“…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca²⁺ entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …”

Acute intense fatigue does not modify the effect of EVA and TPU custom foot orthoses on running mechanics, running economy and perceived comfort by Ken Van Alsenoy (14150559)

“…Flight time shortened (P = 0.026), peak braking (P = 0.016) and push-off (P = 0.032) forces decreased and vertical stiffness increased (P = 0.014) from before to after the repeated-sprint exercise, independent of footwear condition. …”

An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im... by Khreibi, Rima Abou

“…In terms of United Arab Emirates University (UAEU), there has been a decrease in STEM programs enrolment, while STEM graduates in UAEU has stayed steady at 1/3 STEM majors compared to 2/3 non-STEM programs. …”
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Clinical reappraisal of the composite international diagnostic interview version 3.3 in Qatar's National Mental Health Study by Salma M. Khaled (13847737)

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... by Haidong, Wang

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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shehaby, Wassim N.

“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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A new One Health Framework in Qatar for future emerging and re-emerging zoonotic diseases preparedness and response by Devendra, Bansal

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Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma by Shebaby, W.

“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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Assessment of tropospheric NO₂ concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–202... by Yasir E. Mohieldeen (22155901)

“…Analysis of annual NO₂ levels from 2019 to 2023 showed an increase in 2022 compared to that of the previous three years and a clear decrease in 2023 post the completion of the world cup preparations and hosting. …”

Effect of StarD13 on colorectal cancer proliferation, motility and invasion by Nasrallah, Anita

“…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …”
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Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 by Jonathan M. Kocarnik (7512677)

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro by Rizk, Sandra

“…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression by Rayanah Barnawi (8737584)

“…Herein, fascin ShRNA was used to generate stable fascin knockdown (FSCN1^KD) in the MDA-MB-231 TNBC cell line and then were subjected to comprehensive mRNA and miRNA transcriptome analysis. …”

Optical coherence tomography findings in autoimmune retinopathy by Abazzari, Azin

“…Macular OCT showed reduced central macular and foveal thicknesses in 6 patients (mean thickness 143 ± 30 μm and 131 ± 29 μm respectively). …”
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Reducing terrorism with development ; the United Nations' new path. (c2009) by Kassis, Maria-Rita

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Allergen immunotherapy for atopic dermatitis: Systematic review and meta-analysis of benefits and harms by Juan José, Yepes-Nuñez

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Addressing bias in the definition of SARS-CoV-2 reinfection: implications for underestimation by Hiam Chemaitelly (439114)

Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model by Sahar Isa Da’as (18288880)

“…These knockout zebrafish displayed significant morphological heart alterations related to a significant decrease in ventricular and atrial diameters at systolic and diastolic states at the larval stages. …”