Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

“…In addition, treated tumors showed significant dose-dependent decrease in mitotic activity index by 36.5% and 51% in comparison with the control group. …”

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

“…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …”

Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) by Khalil, Nathalie

“…In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. Sensitivity to arginine depletion using HuArgI (Co)-PEG5000 was evident in all of the tested PC cell lines with IC50 values in the pM range at 72 hours following treatment. …”
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Curcumin encapsulated colloidal amphiphilic block co-polymeric nanocapsules by Bechnak, Linda

“…The nanocapsules exhibited a >30–fold decrease in IC50, suggesting enhanced anticancer activity associated with curcumin encapsulation. …”
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1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH by Elhilali, Mostafa

“…In the Phase I study, mean IPSS showed a decrease of 6.5 points (34%), mean QoL a decrease of 2 points (44%) and mean prostate volume a decrease of 5.5 cc (13%) at 12-months compared to screening. …”
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The Antioxidant and Pro-apoptotic effects of Sternbergia clusiana Bulb Ethanolic Extract on Breast Cancer Cells in vitro by El Samarji, Mona

“…The prominent decrease in ROS levels upon treatment confirmed the antioxidant property of the extract being investigated, highlighting the promising effect of SbBEE in breast cancer treatment.…”
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro by Rizk, Sandra

“…However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …”
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”

Exploring The Effect of [HuArgI (Co)-PEG5000]-Induced Autophagy on The Migration, Adhesion, And Invasion of U87 Glioblastoma cells by Haidar, Sara

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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent by Nasreddine, Ghenwa

“…Addition of excess L-citrulline rescued only one of three cell lines tested, indicating that the majority of cell lines are completely auxotrophic for arginine. …”
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"Development of Authentic Annual and Seasonal Lightning Thunderstorms Day Maps for Saudi Arabia" by Shwehdi, M. H.

“…Based on this map, the distribution of thunderstorms over Saudi Arabia is analysed in terms of the factors related to the lightning performance of transmission lines such as thunderstorm days per year (Td/yr). …”
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"Thunderstorm distribution and frequency in Saudi Arabia" by Shwehdi, M. H.

“…Based on this map, the distribution of thunderstorms over Saudi Arabia is analysed in terms of the factors related to the lightning performance of transmission lines such as thunderstorm days per year (Td/yr). …”
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Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma by Shebaby, W.

“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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The antioxidant and anticancer effects of Wild Carrot oil extract by Shebaby, Wassim Nasri

“…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …”
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Managing Endothelial Dysfunction in COVID-19 by Matli, Kamal

“…Secondary outcomes included the composite outcome of ICU admission or the need for mechanical ventilation, all-cause mortality, and the occurrence of side effects Results Of 42 randomized patients, 37 were included in the primary analysis. The mean age of the patients was 57 years; the mean BMI of study participants was 29.14. …”
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An improved non-dimensional model of wet-cooling towers by QURESHI, BILAL AHMED

“…The solution still consists of adjusting the assumed straight air-saturation line to the real air-saturation data, but a new constant (H) is added as well. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells by Shebaby, Wassim N.

“…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …”
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells by Ali Alhoshani (3720718)

“…</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …”

The Assessment of Wind Power for Electricity Generation in Lebanon by Elkhoury, Michel

“…Implementing such wind farms would greatly decrease the harmful emission of greenhouse gases produced by the energy sector devoted to electricity generation by fuel (El-Fadel et al., 2003). …”
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