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The Antioxidant and Pro-apoptotic effects of Sternbergia clusiana Bulb Ethanolic Extract on Breast Cancer Cells in vitro
Published 2021“…Among the various Amaryllidaceae species, Sternbergia clusiana has been recently given a great amount of attention in the medicinal field due to its richness in small chemical molecules, namely Amaryllidaceae alkaloids; these have been reported to possess an antioxidant and anti-inflammatory role, in addition to a prominent anti-cancer effect on different types of cancer cell lines. The current study investigates the selective anti-proliferative effect of Sternbergia clusiana bulb ethanolic extract (SbBEE) on breast cancer cells cultured in vitro (MDA-MB-231 and MCF-7) and reveals the underlying mechanism responsible for the induction of cell death. …”
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Drug-free phototherapy of superficial tumors
Published 2021“…When tested on a DMBA/TPA skin carcinogenesis model, a 90-min exposure to white light thrice weekly resulted in a significant decrease in tumor volumes/incidence compared to control and cisplatin groups, and restored normal morphological features, as confirmed by histopathology. …”
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247
Writing and publishing language studies in the Arab region [Khitabaat Journal]
Published 2024“…Klein starts from an implicit assumption that writing and reading are individual activities and suggests that (individual) writers must decrease their production to enable their (individual) readers to read it. …”
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Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats
Published 2016“…Diabetic rats were injected intraperitonially with 0.03 μg exendin-4/kg body weight/daily or treated with 5 ppm selenium in drinking water for a period of 4 weeks. Results obtained indicate that GLP-1R and IRS-1 levels decreased while the level of preproinsulin mRNA increased in the pancreas of diabetic untreated rats, as compared to control rats. …”
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249
A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge
Published 2021“…Patients were followed for 6 weeks to trace early postoperative complications (infection, dehiscence, and necrosis) and the establishment of protective sensation (pain and temperature).…”
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A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats
Published 2022“…Both extracts were administered to different rat groups via gavage (0.6 g/kg b.w.) before PC treatment (2 g/kg b.w.) three times a week for 3 weeks. The PC intoxication altered the serum biomarkers, the oxidative status, and the Tumor necrosis factor alpha (TNF-α), Bax and Bcl-2 protein expressions of tested animals. …”
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Chiropractic manipulations gone wrong
Published 2016“…He was discharged from the hospital three weeks after he was admitted to begin rehabilitation. …”
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Independent and Combined Effects of Antioxidant Supplementation and Circuit Resistance Training on Selected Adipokines in Postmenopausal Women
Published 2019“…Participants in experimental groups either performed CRT (3 sessions per week with intensity at 55% of one-repetition maximum) or supplemented with Zataria Multiflora (500 mg every day after breakfast with 100 ml of water), or their combination, for 8 weeks. …”
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Relationship between Asymmetry Indices, Anthropometric Parameters, and Physical Fitness in Obese and Non-Obese High School Students
Published 2022“…Body composition, measurements of vertical jump height using a countermovement jump test (CMJ), and dynamic single stance balance using the Y-balance test (YBT), were collected over 4 weeks. Hierarchical multiple linear regression analyses were used as dimension reduction techniques in four different blocks to determine valid predictors for AIs. …”
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Grid electricity demand reduction through applying passive and active strategies for a house in Baghdad, Iraq
Published 2013“…By adopting 1Pearl, it provided 4.33% energy reduction while 2 Pearls can achieve about 4.37% decrease in energy. This means that roof insulation should take priority when considering the passive solutions for conserving energy. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …”
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Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
Published 2014“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
Published 2011“…However, sunitinib did not induce apoptosis in either cell line at any time point, indicating that the anti-migratory effects of sunitinib were not due to impeding cell survival. …”
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