Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 حسب Stein Emil, Vollset

"…In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. …"
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... حسب Michael, Brauer

"…Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2·5th and 97·5th percentile values across the draws. …"
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Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models حسب Ben Romdhane, Haifa

"…An extended dataset will enable a means to independently validate the defined models and test other modelling approaches. …"
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Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient حسب Iman Hawari (12561958)

"…</p><h3>Hypothesis</h3><p dir="ltr">1) LRBA deficiency in the patient leads to decreased surface CTLA-4 expression level and therefore immune mediated type 1 diabetes mellitus. 2) LRBA protein may be involved in the insulin biosynthesis and secretion in β-cells.…"

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... حسب Katherine R Paulson (8674293)

"…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global U5MR decreased from 71·2 deaths per 1000 livebirths (95% uncertainty interval [UI] 68·3–74·0) in 2000 to 37·1 (33·2–41·7) in 2019 while global NMR correspondingly declined more slowly from 28·0 deaths per 1000 live births (26·8–29·5) in 2000 to 17·9 (16·3–19·8) in 2019. …"

Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study حسب Obaidullah Zafar (17910572)

"…Hemoglobin levels significantly increased from 6.4 to 11.1 g/dl (<i>p</i> < 0.001) after IV iron treatment, as did ferritin levels, while total iron-binding capacity decreased. No complications, mortality, or morbidity were reported. …"

3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction حسب Masoud Forsat (14158980)

"…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. At first, simulation implemented on the comparison of the ground movements in the single and twin tunnels. …"

miRNA-dependent regulation of STIM1 expression in breast cancer حسب Rashmi P. Kulkarni (18618634)

"…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …"

Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity حسب Qinji Zhou (18513741)

"…Mice with conditional knockout (cKO) of Celsr3 in postnatal PCs exhibit deficit in motor coordination and learning, atrophic PC dendrites, and decreased synapses. Whole-PC recording in cerebellar slices discloses a reduction frequency of mEPSC and defective postsynaptic plasticity (LTP and LTD) in Celsr3 cKO mutants. …"

Novel proteins implicated in lipid metabolism disorders حسب Nature Research (16552612)

"…After feeding, its expression is decreased, promoting the uptake of dietary lipids in fat tissue. …"

The cost associated with the development of the antimicrobial stewardship program in the adult general medicine setting in Qatar حسب Dina Abushanab (10696501)

"…May 2015-April 2016), and developed ASP was defined as the last 12 months of a 5-year ASP implementation in Hamad Medical Corporation (HMC) (i.e. …"

On the Performance of the Node Control Volume Finite Element Method for Modeling Multi-phase Fluid Flow in Heterogeneous Porous Media حسب Abdul Salam Abd (14151648)

"…Material properties are defined on elements, while transport is simulated on the control volumes. …"

CRISPR-Cas Controls Cryptic Prophages حسب Sooyeon Song (4891132)

"…We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. Specifically, compared to the wild-type strain, reducing the amounts of specific interfering RNAs (crRNA) decreases growth by 40%, increases cell death by 700%, and prevents persister cell resuscitation. …"

Cost-benefit analysis of antimicrobial stewardship program in a cancer setting in Qatar حسب Dina Abushanab (10696501)

"…Cost avoidance was the expenses saved due to decreased hospital stays and fewer adverse drug events (ADEs). …"

Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas حسب Tejedor, Alejandro

"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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Resilience-uncertainty nexus in building energy management integrated with solar system and battery storage حسب Hasan Mehrjerdi (16869957)

"…The energy resilience is improved and the energy cost is decreased at the same time while all events and uncertainties are modeled. …"

Global time differences in road traffic injuries among children and adolescents between and 1990 and 2013: Regional and economical perspectives from global burden of diseases study حسب Uzma Rahim Khan (19794408)

"…<p dir="ltr">In 2010, road traffic injuries (RTIs) are the leading cause of deaths in those aged 1-19 years globally and half of those victims are vulnerable road users (VRUs), defined as pedestrians, bicyclists and motorcyclists. …"

Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings حسب Khan, M.S.

"…The impact of corrosion is widespread, affecting structures, equipment, and infrastructure across various industries increasing the maintenance cost and thereby decreasing profit and efficiency. Nickel-based coatings are one of the most tempting options owing to their enhanced mechanical and corrosion-resistant properties. …"
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …"

Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers حسب Farhat Abbas (5480)

"…For the two-region model, dispersion coefficients were well defined and remained unchanged from the convective–diffusion equation for potassium ions but decreased for bromide ions. …"