Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

“…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …”

Past, present and future global mangrove primary productivity by Mark Chatting (5728340)

“…This study used existing data on mangrove <u>leaf litter</u> to model mangrove Net Primary Productivity (NPP) on a monthly timescale from 1980 to 2094 across global regions defined by the Marine Ecoregions of the World framework. …”

Short-term outcomes of anterior cruciate ligament reconstruction with or without lateral tenodesis or anterolateral ligament reconstruction: a retrospective cohort by Ashraf T. Hantouly (14150319)

“…However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.…”

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”

Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis by Charbel Abi Khalil (14150028)

“…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …”

Run Rules-Based EWMA Charts for Efficient Monitoring of Profile Parameters by Ali Yeganeh (16624998)

“…The proposed EWMAR chart with run rules exhibits a much better performance in detecting small and decreasing shifts than the other competing charts. Finally, an example from multivariate manufacturing industry is employed to illustrate the superiority of the EWMAR chart with run rules.…”

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension by Thiruveni Ramkumar (17075051)

“…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …”

Effect of COVID-19 on the Generation of Waste in Marrakech, Morocco by Abdellah Ouigmane (18460623)

“…</p><h3>Discussion</h3><p dir="ltr">The degree to which the tonnage of household waste decreased depended on the standard of living in each district which was defined by housing type. …”

Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... by Muhanad Alhujaily (11630107)

“…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…”

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

“…We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. …”
Get full text
Get full text
Get full text

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

“…In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …”

Impact of Life-coaching on Students' Wellbeing and Engagement Levels in a Preparatory School in Qatar by Abderrahmane Dedeche (20773958)

“…However, the decrease was overall slighter with coaching group students. …”

Fourier Transform Infrared Imaging—A Novel Approach to Monitor Bio Molecular Changes in Subacute Mild Traumatic Brain Injury by Fazle Rakib (5768069)

“…<div><p>Traumatic brain injury (TBI) can be defined as a disorder in the function of the brain after a bump, blow, or jolt to the head, or penetrating head injury. …”

Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects by Majdi Mansouri (16869885)

“…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …”

Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals by Angy, Mallah

“…Knowledge scores were higher among nurses holding a graduate degree (mean = 85; p < 0.05), and those who attended a training course (mean = 79; p < 0.05). …”
Get full text
Get full text
Get full text

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”

Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained? by Wahiba Elhag (5245547)

“…Mean HbA1c significantly decreased from 8.1%preop to 6.77%_{year 9}. …”

Forecast of the outbreak of COVID-19 using artificial neural network: Case study Qatar, Spain, and Italy by Moayyad Shawaqfah (17280637)

“…The model sensitivity was analyzed using the root mean square error (RMSE), the mean absolute percentage error and the regression coefficient index R2, which yielded highly accurate values of the predicted correlation for the infected and dead cases of 0.99 for the dates considered. …”

Machine Learning and Carbonate Reservoirs : A Production Data Perspective on Permeability Modelling by Mohamad Faysal Baalbaki (21547373)

“…</p><p dir="ltr">The ANN was rigorously tested, showing remarkable accuracy with the highest mean squared error (MSE) being 7.02 and the lowest MSE being 1.19, demonstrating its capability of modeling permeability. …”

Central and peripheral muscle fatigue following repeated‐sprint running in moderate and severe hypoxia by Nathan Townsend (14779642)

“…No significant differences between conditions for mean distance occurred in set 2. There was a decrease in maximal voluntary contraction torque (Δ = −31.4 ± 18.0 N m, <i>P</i> < 0.001) and voluntary activation (%VA; Δ = −7.1 ± 5.1%, <i>P</i> = 0.001) from Pre- to Post-set 1, but there was no effect of hypoxia. …”