Efficiency of Azithromycin-Loaded Lipid Polymer Hybrid Nano-vehicle as a Repurposing formulation in Colon Cancer Management حسب Tarraf, Vanessa

"…It displayed a safe profile on HT29 cell line, with the coated formulation having the lowest IC50= 24.17 μM at 24 hours that even decreases at longer time intervals, which confirms its potential for colorectal cancer management.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment حسب Farhat, Peter

"…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromes حسب Muhammad Danyal Ahsan (14488278)

"…Cascade testing is critical as relatives found to carry a pathogenic gene variant have the opportunity to pursue targeted cancer risk reduction and early detection, decreasing cancer-associated morbidity and mortality. …"

Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful? حسب Abdalla, Eddie K.

"…Importantly, bevacizumab decreases the incidence and severity of sinusoidal injury with oxaliplatin therapy. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains حسب Riachi, Naji J.

"…Decreased striatal dopamine levels in these latter rat strains were associated with increased dopamine turnover. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

miRNA-dependent regulation of STIM1 expression in breast cancer حسب Rashmi P. Kulkarni (18618634)

"…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …"

Why some firms export? An empirical analysis for manufacturing firms in the MENA region حسب Fakih, Ali

"…Also, they indicate that the propensity to export of these firms decreases with larger domestic market size. The empirical analysis reveals considerable variations in the effects of the determining factors when carrying out the estimation for individual countries.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System حسب Bair, Scott

"…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Power System Transient Stability Assessment Based on Machine Learning Algorithms and Grid Topology حسب Senyuk, Mihail

"…Features of transmission line maintenance were used to increase accuracy of estimation. …"
احصل على النص الكامل

Hemodynamics of small aneurysm pairs at the internal carotid artery حسب Jou, Liang-Der

"…Cerebral aneurysms carry significant risks because rupture-related subarachnoid hemorrhage leads to serious and often fatal consequences. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas حسب Tejedor, Alejandro

"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
احصل على النص الكامل

Elastic Buckling Behavior of Functionally Graded Material Thin Skew Plates with Circular Openings حسب Alashkar, Adnan

"…Moreover, as the opening shifts from the plate’s edge closer to the center, the critical buckling load decreases by 26%. The critical buckling load is also dependent on the power index, as an increase in the power index from 0.2 to 5 reduced the buckling load by 1698 kN. …"
احصل على النص الكامل

Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon حسب Mokhbat, Jacques M.

"…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells حسب Castellino, R.C.

"…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation حسب Sleiman, Sama F.

"…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

‘The newest vital sign among pregnant women attending women wellness and research Centre in Qatar: a cross-sectional study’ حسب Sarah Naja (9954737)

"…Thus, public health officials should focus on delivering tailored health literacy interventions to pregnant women in the country.…"

Microwave-Assisted Solvothermal Synthesis of Mo-Doped TiO₂ with Exceptional Textural Properties and Superior Adsorption Kinetics حسب Yahia H. Ahmad (14340210)

"…The uniform effective heating delivered by microwave heating reduced the reaction time to less than 30 min, representing several orders of magnitude lower than conventional heating methods. …"

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …"

Thalidomide-Revisited: Are COVID-19 Patients Going to Be the Latest Victims of Yet Another Theoretical Drug-Repurposing? حسب Athar Khalil (5906330)

"…In the absence of an effective anti-viral molecule and until the formulation of a successful vaccine, anti-inflammatory drugs might offer a complementary tool for controlling the associated complications of COVID-19 and thus decreasing the subsequent fatalities. Drug repurposing for several molecules has emerged as a rapid temporary solution for COVID-19. …"

Strengthening of thin reinforced concrete slabs with CFRP laminates حسب Hawileh, Rami

"…The preliminary results from this study have shown that, the thin RC slabs can carry significantly higher loads in buildings if externally strengthened with CFRP laminates. …"
احصل على النص الكامل