PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"

Sex differences on quality of life and mental health outcomes when using a brief cognitive-behavioral skill building intervention with adolescent Syrian refugees: a secondary analy... حسب Kazandjian, Chant

"…Males demonstrated a significant decrease in anxiety scores compared to females. Among males only, significant decreases in depression and anxiety scores were observed with significant improvement in total QOL.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways حسب Shehaby, Wassim N.

"…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma حسب Shebaby, W.

"…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition حسب Bouclaous, Carmel

"…All groups showed a decrease in relative intestinal absorption with time. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH حسب Elhilali, Mostafa

"…In the Phase I study, mean IPSS showed a decrease of 6.5 points (34%), mean QoL a decrease of 2 points (44%) and mean prostate volume a decrease of 5.5 cc (13%) at 12-months compared to screening. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effect of cycling and thermal control on the storage and dynamics of a 40-L monolithic adsorbed natural gas tank حسب Prosniewski, Matthew

"…It was found that over the course of 20 cycles, due to the retention of 1.9 kg of non-methane components by the monoliths, the useable volumetric storage dropped 16%, and the amount of gas delivered dropped 10%. A second cycling experiment found that by using thermal control while the system discharged, the mass retention decreased to 0.91 kg, and the useable volumetric storage and delivered mass only dropped 7% and 5%, respectively. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells حسب Gowtham Kumar Subbaraj (17807615)

"…Morphometric analysis of CAM showed that treatment with nano-formulated water-soluble kaempferol and combretastatin caused a substantial decrease in density, vessel network, branch points, and nets of CAM blood vessels. …"

Cryomyolysis, a new procedure for the conservative treatment of uterine fibroids حسب Zreik, Tony

"…Normal uterine volume ranged from 35.6 to 548.7 ml preoperatively and 45.1 to 729.6 ml postoperatively (mean increase 40%); however, myoma volume showed a mean decrease of 6% (range-87-28%). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

An improved non-dimensional model of wet-cooling towers حسب QURESHI, BILAL AHMED

"…The solution still consists of adjusting the assumed straight air-saturation line to the real air-saturation data, but a new constant (H) is added as well. …"
احصل على النص الكامل

BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells حسب Ali Alhoshani (3720718)

"…</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …"

Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis حسب Charbel Abi Khalil (14150028)

"…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …"

Sequential therapy in patients receiving Fluoroquinolones at the American University of Beirut Medical Center. (c2001) حسب Homsi, Maria

"…Date of switch (if applicable), oral antibiotic chosen, mean time to switch, mean hospital duration, and mean treatment duration were also recorded. …"
احصل على النص الكامل
احصل على النص الكامل

Risk Factors for Post-Cesarean, Surgical Site Infections in a Multi-Ethnic Population of Qatar حسب Sufia Athar (14777830)

"…</p><h3>Results</h3><p dir="ltr">8,372 women delivered by Cesarean section during the study timeframe. …"

Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer حسب Adviti Naik (673163)

"…Silencing LDHC in breast cancer cell lines (MDA-MB-468, BT-549, HCC-1954) enhanced early T cell activation and cytolytic activity. …"

The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function حسب MUBARAK, ALIA MARJAN

"…These mega-projects may include the construction of major buildings, roads, railway lines and airports. The success of these public initiatives may create the course for the government to decrease its reliance on other sectors. …"
احصل على النص الكامل

Rescue cerclage حسب Khoury, Alfred

"…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension حسب Thiruveni Ramkumar (17075051)

"…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …"

Investigating the moderating role of Export PromotionProgrammes using evidence from North-Africa حسب Yacine Haddoud, Mohamed

"…Findings– Theresults show that while internal barriers decrease firms’ export propensity, EPPs including trade fairs and showsmayindependentlypose eitherapositive ornegativeinfluenceonsuch relationships. …"
احصل على النص الكامل

The effect of bullying-themed literature on the bullying behavior of upper elementary students in Lebanon. (c2012) حسب Bazzy, Anissa

احصل على النص الكامل
احصل على النص الكامل